Cystic Fibrosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-11-05Clinical Trial Update: AeroVanc in the Treatment of Methicillin-resistant Staphylococcus Aureus Infection in Patients With Cystic Fibrosis [Phase 3]
Phase 3 trial update for AeroVanc in MRSA-infected cystic fibrosis patients has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: Evaluation of VX 445/TEZ/IVA in Cystic Fibrosis Subjects 6 Through 11 Years of Age [Phase 3]
A Phase 3 trial update on VX-445/TEZ/IVA (elexacaftor/tezacaftor/ivacaftor) in children aged 6-11 with cystic fibrosis has completed with re…
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CLINICAL_TRIALS trial_result · 2021-10-11Clinical Trial Update: Trial of Inhaled Molgramostim in Cystic Fibrosis Subjects With Nontuberculous Mycobacterial Infection [Phase 2]
Phase 2 trial of inhaled molgramostim in cystic fibrosis patients with non-tuberculous mycobacterial infection was terminated; results poste…
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: DPI-Tobra-Kind Cyclops® in Children With Cystic Fibrosis [Phase 1, Phase 2]
A clinical trial update for DPI-Tobra-Kind Cyclops® in children with cystic fibrosis across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2021-10-01Clinical Trial Update: : TRANSITION: An Observational Study of Transition From Lumacaftor/Ivacaftor to Tezacaftor/Ivacaftor (Tez/Iva)
Observational study assessing transition from Lumacaftor/Ivacaftor to Tezacaftor/Ivacaftor in cystic fibrosis patients; completed with poste…
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CLINICAL_TRIALS trial_result · 2021-09-28Clinical Trial Update: Clinical Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of POL6014 in Patients With CF [Phase 1, Phase 2]
Clinical study evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of POL6014 in cystic fibrosis patients completed.
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Prevention of Bronchiectasis in Infants With Cystic Fibrosis [Phase 3]
Phase 3 trial update on preventing bronchiectasis in infants with cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2021-09-13Clinical Trial Update: I Change Adherence & Raise Expectations [Phase 3]
A Phase 3 clinical trial involving cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis [Phase 3]
Phase 3 clinical trial evaluating short antibiotic combination courses followed by aerosols in cystic fibrosis was terminated.
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Phase 2 Combination Study With Escalating Doses of MS1819-SD on Top of a Stable Dose of PPEs [Phase 2]
Phase 2 trial evaluating escalating doses of MS1819-SD added to a stable dose of PPEs in cystic fibrosis patients; study completed.
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CLINICAL_TRIALS trial_result · 2021-08-18Clinical Trial Update: A Study Evaluating the Efficacy and Safety of VX-445/Tezacaftor/Ivacaftor in Cystic Fibrosis Subjects, Homozygous for F508del [Phase 3]
Phase 3 trial evaluating VX-445/tezosacaftor/ivacaftor in cystic fibrosis patients homozygous for F508del has completed; results posted in 2…
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CLINICAL_TRIALS trial_result · 2021-07-29Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation [Phase 2]
Phase 2 study evaluating VX-371 for safety and efficacy in cystic fibrosis patients with F508del-CFTR mutation has completed with results po…
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CLINICAL_TRIALS trial_result · 2021-07-26Clinical Trial Update: Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF) [Phase 2]
Phase 2 trial investigating ENaC inhibition to clear lungs in cystic fibrosis has completed.
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CLINICAL_TRIALS trial_result · 2021-07-19Clinical Trial Update: A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection [Phase 2, Phase 3]
A Phase 2/Phase 3 trial update evaluating a new posaconazole dosing regimen for paediatric patients with Cystic Fibrosis and Aspergillosis.
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CLINICAL_TRIALS trial_result · 2021-07-02Clinical Trial Update: A Phase 3 Study of VX-445 Combination Therapy in Cystic Fibrosis (CF) Subjects Heterozygous for F508del and a Gating or Residual Function Mutation (F/G and F/RF Genotypes) [Phase 3]
Phase 3 trial update for VX-445 combination therapy in cystic fibrosis patients with F508del and a gating or residual function mutation (F/G…
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: Aerosolized Hypertonic Xylitol Versus Hypertonic Saline in Cystic Fibrosis (CF) Subjects [Phase 1, Phase 2]
A Phase 1/2 trial comparing aerosolized hypertonic xylitol to hypertonic saline in cystic fibrosis subjects has completed with results poste…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Safety, Tolerability and Efficacy of S-1226 in Cystic Fibrosis and Non CF Bronchiectasis [Phase 2]
Phase 2 clinical trial evaluating safety, tolerability, and efficacy of S-1226 in cystic fibrosis and bronchiectasis.
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CLINICAL_TRIALS trial_result · 2021-06-04Clinical Trial Update: A 4-week Study to Test Different Doses of BI 1265162 in Adolescents and Adults With Cystic Fibrosis Using the Respimat® Inhaler - BALANCE - CF™1 [Phase 2]
Phase 2 trial assessing multiple doses of BI 1265162 in adolescents and adults with cystic fibrosis using the Respimat inhaler; study termin…
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Open Label Extension to Bridging Study CTBM100C2303 [Phase 3]
Open-label extension to a bridging Phase 3 study for Pseudomonas aeruginosa and cystic fibrosis was completed with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-04-22Clinical Trial Update: A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis [Phase 2]
Phase 2 trial of VX-659 combination therapy in cystic fibrosis has completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-04-14Clinical Trial Update: A Study of the Dosing, Efficacy, and Safety of Oral Cysteamine in Adult Patients With Cystic Fibrosis Exacerbations [Phase 2]
Phase 2 trial evaluating dosing, efficacy, and safety of oral cysteamine in adults experiencing cystic fibrosis exacerbations has completed …
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CLINICAL_TRIALS trial_result · 2021-04-05Clinical Trial Update: Gut Imaging for Function & Transit in Cystic Fibrosis Study 1
Completed clinical trial evaluating gut imaging for function and transit in cystic fibrosis; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-03-30Clinical Trial Update: Metabolic Efficiency of Combined Pancreatic Islet and Lung Transplant for the Treatment of End-Stage Cystic Fibrosis [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating metabolic efficiency of combined pancreatic islet and lung transplant for end-stage cystic fibrosis; …
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CLINICAL_TRIALS trial_result · 2021-03-16Clinical Trial Update: Detection of Pseudomonas Aeruginosa in the Airways of Patients With CF [NA]
A completed clinical trial examining detection of Pseudomonas aeruginosa in the Airways of patients with cystic fibrosis, with results poste…
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: Testing the Effect of Adding Chronic Oral Azithromycin to Inhaled Tobramycin in People With Cystic Fibrosis (CF) [Phase 4]
Phase 4 trial updating the effects of adding chronic oral azithromycin to inhaled tobramycin in people with cystic fibrosis.