Cushing Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and pharmacokinetics of CRN04894 for Cushing's syndrome and related ACTH-dependent conditio…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Quality of Life, Fatigue and Cognitive, Affective and Emotional Dysfunction in Patients With Cushing's Syndrome
This clinical trial update describes a study evaluating quality of life, fatigue, and cognitive, affective, and emotional dysfunction in pat…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: Cushing's Syndrome Before and After Treatment (CORRECT)
This is a clinical trial update for CORRECT studying Cushing syndrome before and after treatment; the study is sponsored by the University o…
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CLINICAL_TRIALS research · 2025-03-24Clinical Trial Update: Type 2 Diabetes, Obesity and Cortisol Excess
A clinical trial sponsored by Istituto Auxologico Italiano is currently recruiting participants with type 2 diabetes, obesity, and cortisol …
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Osilodrostat for the Treatment of Non-Cushing's Disease Cushing's Syndrome
A completed clinical trial evaluating osilodrostat for the treatment of Cushing's syndrome has posted results.
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Effect of Metyrapone on Cardiovascular Risk Factors in Patients With Adrenal Incidentalomas and Cushing's Syndrome [Phase 4]
This clinical trial update reports a Phase 4 study evaluating the effect of metyrapone on cardiovascular risk factors in patients with adren…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Roll-over Study in Patients With Endogenous Cushing's Syndrome for LCI699 [Phase 2]
Completion of a Phase 2 roll-over trial evaluating LCI699 (osilodrostat) in patients with endogenous Cushing's syndrome. Results for the stu…
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CLINICAL_TRIALS research · 2024-12-16Clinical Trial Update: NAC- NAFLD and Cushing [NA]
A recruiting clinical trial at University Hospital Angers evaluating N-acetylcysteine for non-alcoholic fatty liver disease and Cushing synd…
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EMA approval · 2024-12-12EMA Authorised: Isturisa (osilodrostat phosphate) — Recordati Rare Diseases
The European Medicines Agency authorised Isturisa (osilodrostat) for the treatment of Cushing syndrome, with Recordati Rare Diseases as the …
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Dynamic Hormone Profiling and Multimodal Data Capture in Primary Aldosteronism
A study update from Haukeland University Hospital on dynamic hormone profiling and multimodal data capture in primary aldosteronism and rela…
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CLINICAL_TRIALS research · 2024-06-11Clinical Trial Update: Neuroendocrine Mechanisms in Adiposity: An Integrated Approach to the Characterization of Potential Pharmacological Novel Targets Based on Experimental and Clinical Models
The study aims to characterize neuroendocrine mechanisms of adiposity to identify potential pharmacological targets using integrated experim…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Novel Mediators of the Lipodystrophy and Metabolic Consequences of Cushing's Disease
Columbia University led a study investigating novel mediators of lipodystrophy and metabolic consequences in Cushing's syndrome. The trial s…
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FDA approval · 2023-08-16FDA Approved: RECORLEV — Supplemental Application (Xeris Pharmaceuticals, Inc.)
The FDA approved a supplemental application for RECORLEV (levoketoconazole) submitted by Xeris Pharmaceuticals, Inc.
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FDA approval · 2023-01-03FDA Approved: MIFEPRISTONE — Supplemental Application (GenBioPro, Inc.)
The FDA approved GenBioPro, Inc.'s supplemental application for Mifepristone, resulting in updated labeling.
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FDA approval · 2021-12-30FDA Approved: RECORLEV — Original Application (Xeris Pharmaceuticals, Inc.)
FDA approved Recorlev (levoketoconazole) by Xeris Pharmaceuticals as an original approval for the treatment of adults with endogenous Cushin…
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FDA approval · 2021-05-14FDA Approved: MIFEPRISTONE — Supplemental Application (GenBioPro, Inc.)
FDA approved GenBioPro, Inc.'s supplemental application for mifepristone, confirming its continued availability for established indications …
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome [Phase 2]
Phase 2 trial of ATR-101 for endogenous Cushing's syndrome was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-25Clinical Trial Update: New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome [Phase 2]
Phase 2 trial assessing new imaging techniques for evaluating patients with ectopic Cushing syndrome.
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome [Phase 3]
Phase 3 trial assessing metyrapone in patients with endogenous Cushing's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome [Phase 2]
Phase 2 trial update on osilodrostat for Cushing's syndrome, reporting efficacy and safety results.
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FDA approval · 2020-02-20FDA Approved: METOPIRONE — Supplemental Application (HRA Pharma Rare Diseases)
FDA approved a supplemental application for METOPIRONE (metyrapone) submitted by HRA Pharma Rare Diseases, resulting in an updated indicatio…
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FDA approval · 2019-11-05FDA Approved: MIFEPRISTONE — Supplemental Application (Corcept Therapeutics Incorporated)
The FDA approved a supplemental application for mifepristone submitted by Corcept Therapeutics Incorporated.
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CLINICAL_TRIALS trial_result · 2019-09-25Clinical Trial Update: Study to Evaluate CORT125134 in Participants With Cushing's Syndrome [Phase 2]
Phase 2 trial update for CORT125134 in participants with Cushing's syndrome; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: Biomarker Expression in Patients With ACTH-Dependent Cushing's Syndrome Before and After Surgery
This completed clinical trial reports on biomarker expression in patients with ACTH-dependent Cushing's syndrome before and after surgery.
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CLINICAL_TRIALS research · 2019-01-18Clinical Trial Update: The Accuracy of Late Night Urinary Free Cortisol/Creatinine and Hair Cortisol in Cushing's Syndrome Diagnosis
A clinical trial update evaluating how accurately late-night urinary free cortisol/creatinine and hair cortisol tests diagnose Cushing syndr…