Cushing Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Extension Study to Evaluate the Safety of Long-Term Use of Relacorilant in Patients With Cushing Syndrome [Phase 2]
A Phase 2 extension study is evaluating the long-term safety of relacorilant in patients with Cushing syndrome, and the trial is currently a…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D) [Phase 2]
A Phase 2 clinical trial called CAPTAIN-T2D by Sparrow Pharmaceuticals is currently recruiting for patients with type 2 diabetes and cortiso…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Prospective Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Ectopic Cushing Syndrome [Phase 2]
A Phase 2 clinical trial evaluating imaging with 68Ga-DOTATATE PET/CT, Octreotide, and F-DOPA PET for ectopic Cushing syndrome due to ACTH, …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
A completed clinical trial update investigating the genetic basis of primary pigmented nodular adrenocortical disease (PPNAD) and the Carney…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome [Phase 2]
The document describes a Phase 2 clinical trial evaluating the pharmacokinetics, pharmacodynamics, and tolerability of osilodrostat in pedia…
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CLINICAL_TRIALS research · 2026-01-20Clinical Trial Update: Diagnostic Value of CXCR4-targeted PET/CT in ACTH-dependent and Independent Cushing's Syndrome [Phase 1, Phase 2]
An early-phase clinical trial evaluating CXCR4-targeted PET/CT imaging for diagnosing Cushing's syndrome (both ACTH-dependent and ACTH-indep…
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism
A completed clinical trial suggests that contralateral adrenal volume may predict the duration of postoperative steroid replacement therapy …
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome [Phase 4]
Osilodrostat is being studied in a Phase 4 trial for hypertension caused by hypercortisolemia due to Cushing's syndrome. The study status is…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Evaluating the Functional Status of the Adrenal Glands With [68Ga]Ga-PentixaFor in Hyperaldosteronism and Hypercortisolism [Phase 2]
Phase 2 clinical trial evaluating [68Ga]Ga-PentixaFor PET imaging to assess adrenal gland function in hyperaldosteronism and hypercortisolis…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Discriminant Capacity and Thresholds of Salivary Cortisol in Chemiluminescence in the Diagnosis of Hypercorticisms
This clinical trial evaluates the diagnostic performance of salivary cortisol measured by chemiluminescence to distinguish hypercorticism. I…
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FDA approval · 2025-11-04FDA Approved: ISTURISA — Supplemental Application (Recordati Rare Diseases, Inc.)
The FDA approved a supplemental application for Isturisa (osilodostat) submitted by Recordati Rare Diseases, Inc.
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome [Phase 2]
Phase 2 clinical trial evaluating the performance of the desmopressin stimulation test in ACTH-dependent Cushing syndrome. The study is curr…
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CLINICAL_TRIALS research · 2025-10-23Clinical Trial Update: Collecting Information About Treatment Results for Patients With Cushing's Syndrome
A clinical trial is enrolling to collect information about treatment results for patients with Cushing's Syndrome and Cushing's Disease.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome [Phase 2]
Phase 2 study of SPI-62 in ACTH-dependent Cushing's syndrome (Cushing disease) has completed. The document lists Sparrow Pharmaceuticals as …
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal Tumors
This document reports enrollment status for a comparative study of perioperative cardiac injury in patients with functional adrenal tumors, …
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Establishment and Clinical Application of Reference Intervals of Salivary Cortisol
The trial aims to establish reference intervals for salivary cortisol and assess their clinical application in healthy adults and patients w…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)
A Mayo Clinic-led clinical trial is recruiting to study recovery from Cushing syndrome and Mild Autonomous Cortisol Secretion (MACS).
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Adrenal Tumors - Pathogenesis and Therapy
This clinical trial update indicates that a study on the pathogenesis and therapy of adrenal tumors is currently recruiting, covering condit…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
Preclinical immunotherapy program for adrenocortical carcinoma is described, with Cushing's syndrome listed as a condition; the trial status…
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas [Phase 3]
Phase 3 results are reported for relacorilant in patients with cortisol-secreting adrenal adenomas causing hypercortisolism, evaluating its …
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Open-label Treatment in Cushing's Syndrome [Phase 3]
A Phase 3 open-label trial for Cushing's syndrome and Cushing disease sponsored by Cortendo AB has completed, with results posted in June 20…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Modified Desmopressin (mDesmo) Using Cold-Kit for PET/CT
This clinical trial update reports recruitment for a study evaluating modified desmopressin (mDesmo) with a Cold-Kit for PET/CT imaging in p…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Continuous Steroid Monitoring in Interstitial Fluid With Wearable and Nanoparticle-enhanced Biosensors for Improved Management of Adrenal Disorders [NA]
This study investigates continuous monitoring of steroid levels in interstitial fluid using a wearable sensor platform and nanoparticle-enha…
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EMA approval · 2025-05-05EMA Authorised: Ketoconazole Esteve (previously Ketoconazole HRA) (Ketoconazole) — Esteve Pharmaceuticals, S.A.
The EMA has authorised Ketoconazole Esteve for the treatment of Cushing syndrome.
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome [Phase 3]
Phase 3 study evaluating relacorilant in endogenous Cushing syndrome completed with results posted on 2025-04-24.