Cushing Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-15Clinical Trial Update: Contralateral Adrenal Volume Predicts Duration of Postoperative Steroid Replacement Therapy in Non-ACTH-dependent Hypercortisolism
A completed clinical trial suggests that contralateral adrenal volume may predict the duration of postoperative steroid replacement therapy …
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CLINICAL_TRIALS trial_result · 2025-12-10Clinical Trial Update: Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome [Phase 4]
Osilodrostat is being studied in a Phase 4 trial for hypertension caused by hypercortisolemia due to Cushing's syndrome. The study status is…
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome [Phase 2]
Phase 2 study of SPI-62 in ACTH-dependent Cushing's syndrome (Cushing disease) has completed. The document lists Sparrow Pharmaceuticals as …
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: A Study of the Efficacy and Safety of Relacorilant in Patients With Cortisol-Secreting Adrenal Adenomas [Phase 3]
Phase 3 results are reported for relacorilant in patients with cortisol-secreting adrenal adenomas causing hypercortisolism, evaluating its …
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Open-label Treatment in Cushing's Syndrome [Phase 3]
A Phase 3 open-label trial for Cushing's syndrome and Cushing disease sponsored by Cortendo AB has completed, with results posted in June 20…
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CLINICAL_TRIALS trial_result · 2025-04-24Clinical Trial Update: A Study of the Efficacy and Safety of Relacorilant in Patients With Endogenous Cushing Syndrome [Phase 3]
Phase 3 study evaluating relacorilant in endogenous Cushing syndrome completed with results posted on 2025-04-24.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Osilodrostat for the Treatment of Non-Cushing's Disease Cushing's Syndrome
A completed clinical trial evaluating osilodrostat for the treatment of Cushing's syndrome has posted results.
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Roll-over Study in Patients With Endogenous Cushing's Syndrome for LCI699 [Phase 2]
Completion of a Phase 2 roll-over trial evaluating LCI699 (osilodrostat) in patients with endogenous Cushing's syndrome. Results for the stu…
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CLINICAL_TRIALS trial_result · 2021-03-02Clinical Trial Update: A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome [Phase 2]
Phase 2 trial of ATR-101 for endogenous Cushing's syndrome was terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-25Clinical Trial Update: New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome [Phase 2]
Phase 2 trial assessing new imaging techniques for evaluating patients with ectopic Cushing syndrome.
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome [Phase 3]
Phase 3 trial assessing metyrapone in patients with endogenous Cushing's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome [Phase 2]
Phase 2 trial update on osilodrostat for Cushing's syndrome, reporting efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2019-09-25Clinical Trial Update: Study to Evaluate CORT125134 in Participants With Cushing's Syndrome [Phase 2]
Phase 2 trial update for CORT125134 in participants with Cushing's syndrome; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-01-24Clinical Trial Update: Biomarker Expression in Patients With ACTH-Dependent Cushing's Syndrome Before and After Surgery
This completed clinical trial reports on biomarker expression in patients with ACTH-dependent Cushing's syndrome before and after surgery.
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CLINICAL_TRIALS trial_result · 2018-05-08Clinical Trial Update: Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism [Phase 2]
A National Cancer Institute-sponsored Phase 2 trial comparing adrenalectomy versus observation for subclinical hypercortisolism/Cushing synd…
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CLINICAL_TRIALS trial_result · 2018-03-02Clinical Trial Update: Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism [Phase 4]
A Phase 4 trial evaluating glucocorticoid receptor blockade with mifepristone in patients with mild hypercortisolism has completed and resul…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Alterations of Muscle Secretome Associated With Muscle Atrophy Caused by Glucocorticoids
This completed clinical trial investigates how glucocorticoids alter the muscle secretome and contribute to muscle atrophy in Cushing syndro…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Efficacy and Safety of Posterior Retroperitoneoscopic Adrenalectomy: A Comparative Study [NA]
This completed trial evaluated the efficacy and safety of posterior retroperitoneoscopic adrenalectomy in adrenal diseases, including pheoch…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: A Study to Assess SOM230 in Patients With Pituitary Cushing's Disease [Phase 2]
A Phase 2 study evaluating SOM230 (pasireotide) in patients with pituitary Cushing's disease has completed.
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CLINICAL_TRIALS trial_result · 2016-09-29Clinical Trial Update: Cardiac Steatosis in Cushing's Syndrome [NA]
Clinical trial update focusing on cardiac steatosis in Cushing's syndrome. The current status details are not publicly available.
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CLINICAL_TRIALS trial_result · 2016-08-23Clinical Trial Update: Effects of IL-1 Beta on the HPA-axis in Obese Persons [Phase 3]
Phase 3 trial evaluating the effects of interleukin-1 beta on the HPA axis in obese individuals has completed. It relates to metabolic syndr…
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CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: A Study to Confirm Recurrent or Persistent Cushing's Syndrome in Patients With Signs or Symptoms of Hypercortisolemia
This entry notes the termination of a Corcept Therapeutics-sponsored clinical trial evaluating recurrent or persistent Cushing's syndrome in…
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CLINICAL_TRIALS trial_result · 2014-04-02Clinical Trial Update: An Extension Study of CORLUX in the Treatment of Endogenous Cushing's Syndrome [Phase 3]
An extension study of CORLUX (mifepristone) for endogenous Cushing's syndrome completed, with results posted in 2014.
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CLINICAL_TRIALS trial_result · 2013-11-20Clinical Trial Update: Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome [Phase 3]
Phase 3 trial results for mifepristone (CORLUX) in endogenous Cushing's syndrome have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion [Phase 2]
Phase 2 open-label trial of mifepristone for symptomatic treatment of Cushing's syndrome due to ectopic ACTH secretion; study terminated wit…