Cushing Disease
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Cushing's Disease Complications
This entry notes that a clinical trial investigating complications of Cushing's disease has completed.
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CLINICAL_TRIALS trial_result · 2025-10-08Clinical Trial Update: SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome [Phase 2]
Phase 2 study of SPI-62 in ACTH-dependent Cushing's syndrome (Cushing disease) has completed. The document lists Sparrow Pharmaceuticals as …
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CLINICAL_TRIALS trial_result · 2025-06-19Clinical Trial Update: Open-label Treatment in Cushing's Syndrome [Phase 3]
A Phase 3 open-label trial for Cushing's syndrome and Cushing disease sponsored by Cortendo AB has completed, with results posted in June 20…
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease
This clinical trial update reports long-term safety and efficacy data for pasireotide subcutaneous in patients with Cushing's disease. The s…
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CLINICAL_TRIALS trial_result · 2024-08-28Clinical Trial Update: Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies [Phase 4]
Phase 4 expanded-access study update for pasireotide shows completed status with results posted, enabling access for eligible patients in No…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: Diagnostic Yield of Deep Learning Based Denoising MRI in Cushing's Disease
Clinical trial update on the diagnostic yield of a deep learning-based denoising MRI for Cushing's disease due to pituitary ACTH-secreting a…
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Treatment of Cushing's Disease With R-roscovitine [Phase 2]
Phase 2 trial evaluating R-roscovitine for Cushing's disease has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-10-19Clinical Trial Update: Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease [Phase 3]
Phase 3 clinical trial update evaluating efficacy and safety of osilodrostat in Cushing's disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-06-02Clinical Trial Update: Extension Study to Assess the Safety and Efficacy of Pasireotide in Participants With Cushing's Disease [Phase 2]
Extension study evaluating safety and efficacy of pasireotide in participants with Cushing's disease (Phase 2; completed).
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CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Safety and Efficacy of LCI699 in Cushing's Disease Patients [Phase 2]
Phase 2 trial updates the safety and efficacy of LCI699 for Cushing's disease, with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2020-09-18Clinical Trial Update: Study of the Efficacy and Safety of Pasireotide s.c. +/- Cabergoline in Patients With Cushing's Disease [Phase 2]
Phase 2 clinical trial evaluating pasireotide with or without cabergoline in patients with Cushing's disease; study terminated with results …
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease [Phase 3]
Phase 3 trial update for LCI699 in Cushing's disease reports completed results on safety and efficacy.
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CLINICAL_TRIALS trial_result · 2019-05-29Clinical Trial Update: Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly [Phase 4]
A Phase 4 clinical trial completed in 2019 evaluating management of pasireotide-induced hyperglycemia in adults with Cushing's disease or ac…
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CLINICAL_TRIALS trial_result · 2018-06-19Clinical Trial Update: An Open-label, Multi-center, Expanded Access Study of Pasireotide s.c. in Patients With Cushing's Disease. [Phase 3]
An open-label, multi-center expanded-access Phase 3 trial of subcutaneous pasireotide in patients with Cushing's disease has completed with …
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Effects of Hormone Stimulation on Brain Scans for Cushing s Disease [EARLY_Phase 1]
Phase 1 study evaluating how hormone stimulation affects brain scans in Cushing's disease due to a pituitary neoplasm. The trial status is c…
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CLINICAL_TRIALS trial_result · 2018-04-11Clinical Trial Update: Efficacy and Safety of Pasireotide Administered Monthly in Patients With Cushing's Disease [Phase 3]
A Phase 3 trial evaluating monthly pasireotide for efficacy and safety in Cushing's disease has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Adipokine Profile in Patients With Cushing's Disease on Pasireotide Treatment [Phase 4]
A Phase 4 clinical trial assessing adipokine profiles in patients with Cushing's disease treated with pasireotide has completed.
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CLINICAL_TRIALS trial_result · 2016-02-17Clinical Trial Update: Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease) [Phase 2]
Phase 2 clinical trial investigating rosiglitazone for newly diagnosed ACTH-secreting pituitary tumors (Cushing disease) was terminated with…
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CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: The Factors Associated With the Recurrence in Patients With Cushing Disease
This completed clinical trial analyzes factors associated with recurrence in patients with Cushing disease.
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CLINICAL_TRIALS trial_result · 2013-11-20Clinical Trial Update: Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing's Syndrome [Phase 3]
Phase 3 trial results for mifepristone (CORLUX) in endogenous Cushing's syndrome have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease [Phase 3]
Phase 3 trial evaluating safety and efficacy of different dose levels of pasireotide in patients with de novo, persistent or recurrent Cushi…
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CLINICAL_TRIALS trial_result · 2011-05-30Clinical Trial Update: Preoperative Bexarotene Treatment for Cushing's Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial from University of Virginia evaluating preoperative bexarotene for Cushing's disease.
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CLINICAL_TRIALS trial_result · 2009-04-29Clinical Trial Update: Study of Cabergoline in Treatment of Corticotroph Pituitary Tumor [Phase 3]
A Phase 3 clinical trial evaluating cabergoline for treatment of corticotroph pituitary tumors in Cushing's disease has completed.