Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial Interventions
This clinical trial investigates pressure (fractional flow reserve) and flow (vascular flow reserve) measurements during peripheral arterial…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: BEST vCLI Registry
The BEST vCLI Registry trial sponsored by Duke University focusing on Critical Limb Ischemia has completed.
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Skew Flap vs Long Posterior Flap for Below Knee Amputation Early and Short- Term Outcomes [NA]
A completed clinical trial from Sohag University comparing skew flap versus long posterior flap techniques for below-knee amputation reports…
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CLINICAL_TRIALS trial_result · 2025-06-26Clinical Trial Update: Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia
A completed clinical trial sponsored by Fudan University investigated sarcopenia and peripheral artery disease in patients with critical lim…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Comprehensive Limb Evaluation and Arterial Revascularization With Toe Pressure Optimization Registry [NA]
A clinical trial registry entry for a study evaluating comprehensive limb evaluation and arterial revascularization with toe pressure optimi…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: BGC101 (EnEPC) Autologous Cell Therapy From Patient's Own Blood for Treatment of Critical Limb Ischemia (CLI) [Phase 1, Phase 2]
This clinical trial update reports that BioGenCell's BGC101 (EnEPC) autologous cell therapy is being studied for critical limb ischemia in P…
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: Serrantor OCT Study [NA]
Serrantor OCT Study, sponsored by Cagent Vascular LLC, is currently recruiting patients with Critical Limb Ischemia to evaluate the Serranto…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention
A clinical trial from University Hospitals Cleveland Medical Center is evaluating a thermal imaging camera to assess tissue perfusion before…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Cost Analysis of Vascular Surgical Techniques
This clinical trial update focuses on the cost analysis of vascular surgical techniques used to treat Critical Limb Ischemia.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Effect of Environmental Temperature on Vascular Ultrasound Vein Scan Measurements
A clinical trial investigating whether environmental temperature affects vascular ultrasound vein scan measurements in people with critical …
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Imaging-Guided Vessel Sizing in the Tibial Arteries
This clinical trial update announces the completion of a study evaluating imaging-guided vessel sizing in the tibial arteries for peripheral…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: miRNAs in Critical Limb Ischemia (miRNACLI)
Clinical trial update for the miRNACLI study investigating microRNAs in Critical Limb Ischemia; the trial is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Safety and Efficacy of Allogeneic Adipose Tissue Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia [Phase 2]
Phase 2 trial evaluating the safety and efficacy of allogeneic adipose tissue-derived mesenchymal stem cells in diabetic patients with criti…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemia
A clinical trial evaluating normobaric oxygen therapy for critical limb ischemia is currently recruiting. The sponsor is University Hospital…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: TP03HN106 in Patients With Critical Limb Ischemia [Phase 2]
Phase 2 clinical trial TP03HN106 for critical limb ischemia is currently recruiting, with status indicating ongoing enrollment.
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: FlowMet-R Blood Flow Measurement for the Diagnosis of Peripheral Artery Disease and Critical Limb Ischemia
Clinical trial update on FlowMet-R for diagnosing Peripheral Artery Disease and Critical Limb Ischemia; the study was terminated and results…
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CLINICAL_TRIALS trial_result · 2025-04-06Clinical Trial Update: Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI
This clinical trial compared ultrasound-guided sciatic popliteal nerve block versus an erector spinae plane block for endovascular managemen…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: MOTIV BTK Randomized Controlled Trial [NA]
The document notes a MOTIV BTK randomized controlled trial sponsored by REVA Medical, Inc. that is currently recruiting for Critical Limb Is…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: FAZA PET/MRI in CLI Patients Pre and Post Revascularization [NA]
ClinicalTrials.gov update indicates ongoing recruitment for a FAZA PET/MRI imaging study in patients with Critical Limb Ischemia, assessing …
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Additional Hyperbaric Oxygen After Lower Extremity Amputation [NA]
Clinical trial is evaluating additional hyperbaric oxygen therapy after lower extremity amputation in patients with diabetes-related conditi…
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CLINICAL_TRIALS research · 2025-01-30Clinical Trial Update: Safety, Tolerability, and Biodistribution of [89Zr]Zr-DFO-APAC in Subjects With PAOD/CLI and Healthy Volunteers (Acronyms: 89Zr = Zirconium-89, DFO = Desferrioxamine, APAC = AntiPlatelet AntiCoagulant, PET/CT = Positron Emission Tomography/Computed Tomography) [EARLY_Phase 1]
Early-phase clinical trial update evaluating safety, tolerability, and biodistribution of the Zirconium-89–labeled tracer [89Zr]Zr-DFO-APAC …
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CLINICAL_TRIALS research · 2025-01-28Clinical Trial Update: Tolerance Study of Allogeneic of Adipose Tissue Derived Mesenchymal Stroma/Stem Cells (AdMSC) Transplantation in Patients With Critical Limb Ischemia. [Phase 1]
Phase 1 tolerance study evaluating allogeneic adipose tissue–derived mesenchymal stem/stromal cells (AdMSC) transplantation for critical lim…
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CLINICAL_TRIALS trial_result · 2024-12-12Clinical Trial Update: Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA) [Phase 1]
Phase 1 clinical trial evaluating autologous concentrated bone marrow aspirate to prevent wound complications after below-knee amputation. T…
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CLINICAL_TRIALS research · 2024-12-09Clinical Trial Update: Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating a cell therapy for lower limb ulcers in patients with critical limb ischemia due to peripheral arterial …
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CLINICAL_TRIALS trial_result · 2024-10-18Clinical Trial Update: Safety Study of Gene Therapy in Treating Critical Leg Ischemia [Phase 1]
Phase 1 safety study of a gene therapy for critical limb ischemia has been completed. Results have been posted.