Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia [NA]
Clinical trial PROMISE III evaluating Percutaneous Deep Vein Arterialization for late-stage chronic limb-threatening ischemia; the study is …
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Shockwave ®S4 Catheter IVL to Treat Infrapopliteal Calcified Stenoses and/or Occlusions in CLTI Patients (LEGACY)
The LEGACY trial evaluating the Shockwave S4 catheter intravascular lithotripsy for infrapopliteal calcified stenoses and/or occlusions in p…
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CLINICAL_TRIALS trial_result · 2026-03-10Clinical Trial Update: Ultra-low Dose Contrast for Endovascular Procedures
Clinical trial update indicating completion of a study evaluating ultra-low dose contrast for endovascular procedures.
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CLINICAL_TRIALS trial_result · 2026-02-03Clinical Trial Update: Single Versus Multiple Vessels Endovascular Tibial Arteries Revascularization for Critical Limb Ischemia [NA]
This entry notes the completion of a clinical trial comparing single-versus-multiple-vessel endovascular tibial artery revascularization in …
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CLINICAL_TRIALS trial_result · 2026-01-26Clinical Trial Update: LIFE-BTK PK Sub-study [NA]
Results from Abbott's LIFE-BTK pharmacokinetics sub-study in Critical Limb Ischemia have been posted; the study is currently active but not …
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: PROMISE International [NA]
The document reports that the PROMISE International clinical trial sponsored by LimFlow SA for critical limb ischemia has completed and resu…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Drug Eluting Temporary Spur Stent System vs Percutaneous Balloon Angioplasty for the Treatment of Critical Limb Ischemia [NA]
A clinical trial evaluating a drug-eluting temporary spur stent system versus percutaneous balloon angioplasty for critical limb ischemia is…
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CLINICAL_TRIALS research · 2025-12-31Clinical Trial Update: Nutrition in Patient With Critical Limb Ischemia [EARLY_Phase 1]
Early Phase 1 clinical trial update evaluating nutritional interventions in patients with critical limb ischemia and malnutrition.
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients [NA]
A registered clinical trial evaluating continuous compartment pressure monitoring to prevent compartment syndrome in patients on VA-ECMO; re…
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CLINICAL_TRIALS trial_result · 2025-11-28Clinical Trial Update: Percutaneous Deep Vein Arterialization Post-Market Study [NA]
A completed post-market study evaluating Percutaneous Deep Vein Arterialization for Critical Limb Ischemia has posted results. The sponsor i…
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CLINICAL_TRIALS research · 2025-11-05Clinical Trial Update: CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcified Common Femoral Lesions
Clinical trial update on CRUSH PAD evaluating real-world outcomes of Shockwave intravascular lithotripsy for calcified common femoral lesion…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Peripheral Arterial Disease
An all-comers observational study of the MicroStent Peripheral Vascular Stent System in people with peripheral arterial disease, including c…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Comparative Study of Negative-Pressure Wound Therapy Integrated With Silver Nanoparticle Spray Versus Negative-Pressure Wound Therapy in Post-Revascularization Diabetic Foot Wound Management
A comparative clinical trial is evaluating negative-pressure wound therapy with a silver nanoparticle spray versus negative-pressure wound t…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Buerger's Disease [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of Stempeucel in patients with critical limb ischemia due to thromboangiitis oblit…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial Disease [Phase 4]
This Phase 4 clinical trial update outlines the ongoing evaluation of Stempeucel for critical limb ischemia due to peripheral arterial disea…
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CLINICAL_TRIALS trial_result · 2025-09-05Clinical Trial Update: A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL) [NA]
This clinical trial update reports results from a prospective single-arm multicenter study evaluating the Bare Temporary Spur Stent System f…
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CLINICAL_TRIALS trial_result · 2025-09-03Clinical Trial Update: Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
This trial evaluated diagnostic methods for confirming peripheral arterial disease and determining severity in diabetic patients; results ha…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: DCB Outcomes After Plain or Scoring Balloon for Vessel Preparation in Patients With Femoropopliteal Arterial Disease [NA]
Clinical trial update reporting outcomes of plain versus scoring balloon vessel preparation in patients with femoropopliteal arterial diseas…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Temsirolimus Adventitial Delivery to Improve ANGioplasty and/or Atherectomy Revascularization Outcomes Below the Knee [Phase 3]
Phase 3 clinical trial evaluating adventitial delivery of temsirolimus to improve below-the-knee angioplasty and/or atherectomy revasculariz…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Swedish Drug-elution Trial in Peripheral Arterial Disease [NA]
A clinical trial update from Sweden describes a drug-elution study for peripheral arterial disease. The trial status is active but not recru…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Medium-term Results of Lower Limb Arterial Bypass
This update reports medium-term results from a trial evaluating lower limb arterial bypass for peripheral arterial occlusive disease and cri…
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging [Phase 4]
A Phase 4 clinical trial evaluating intima versus adventitia drug delivery to elucidate restenosis mechanisms, monitored by MRI, has complet…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Follow-up Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-L)
A follow-up gene therapy trial for critical limb ischemia is currently enrolling by invitation, sponsored by Beijing Northland Biotech Co., …
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CLINICAL_TRIALS research · 2025-07-09Clinical Trial Update: Initial Feasibility Study of the STENTiT Resorbable Fibrillated Scaffold (RFS). The RFS is Intended to Restore Lumen Patency and Blood Flow to Infrapopliteal Arteries. The RFS is a Fully Electrospun Tubular Device With a Fibrillated Microarchitecture and Designed for Transcatheter Delivery [NA]
Initial feasibility study of the STENTiT Resorbable Fibrillated Scaffold (RFS), a fully electrospun tubular device designed to restore lumen…
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CLINICAL_TRIALS trial_result · 2025-07-08Clinical Trial Update: IN.PACT BTK Randomized Study to Assess Safety and Efficacy of IN.PACT 014 vs. PTA [NA]
A randomized study comparing IN.PACT 014 paclitaxel-coated balloon to standard PTA in critical limb ischemia and peripheral arterial disease…