Critical Limb Ischemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: Study to Assess the Efficacy and Safety of CLBS12 in Patients with Critical Limb Ischemia (CLI) [Phase 2]
Phase 2 study evaluating CLBS12 for critical limb ischemia has completed. The update covers the trial status in patients with related vascul…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Effect of Acute Cardiovascular Disease on Microbiome
This completed clinical trial from University Hospital Essen investigated how acute cardiovascular disease influences the human microbiome. …
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-2) [Phase 3]
Phase 3 gene therapy trial for critical limb ischemia sponsored by Beijing Northland Biotech has completed.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia [Phase 2]
Phase 2 clinical trial evaluating a Helixmith gene therapy for critical limb ischemia has completed, with safety and efficacy results posted…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia (NL003-CLI-III-1) [Phase 3]
Phase 3 safety and efficacy study of a gene therapy for critical limb ischemia has completed the trial.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: LIFE-BTK Randomized Controlled Trial [NA]
Results for the LIFE-BTK randomized controlled trial in critical limb ischemia have been posted; the study is currently active but not recru…
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CLINICAL_TRIALS withdrawal · 2024-09-19Clinical Trial Update: Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization
Expanded Access treatment program for Critical Limb Ischemia with minor tissue loss in patients unsuitable for revascularization is no longe…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Efficacy and Safety of Mesenchymal Stem Cell Clusters in Patients with Critical Limb Ischemia [Phase 1, Phase 2]
The document reports the completion of a Phase 1/2 clinical trial evaluating the efficacy and safety of mesenchymal stem cell clusters in pa…
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CLINICAL_TRIALS trial_result · 2024-08-30Clinical Trial Update: Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization [Phase 3]
Phase 3 trial evaluating intramuscular PLX PAD for critical limb ischemia with minor tissue loss in patients unsuitable for revascularizatio…
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CLINICAL_TRIALS research · 2024-08-29Clinical Trial Update: Acceleration Time Assessment for Prediction of Critical Limb Ischemia
This clinical trial evaluates acceleration time as a predictor of critical limb ischemia. Recruitment is ongoing at Centre Hospitalier le Ma…
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CLINICAL_TRIALS other · 2024-08-21Clinical Trial Update: Trial to Assess Chelation Therapy in Critical Limb Ischemia [Phase 3]
Phase 3 clinical trial evaluating chelation therapy for critical limb ischemia is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-08-19Clinical Trial Update: Cryopreserved Saphenous Vein Allograft in Patients With Critical Limb Ischemia for Peripheral Revascularization
This document reports the completion status of a clinical trial evaluating cryopreserved saphenous vein allografts for peripheral revascular…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: N-Acetyl-Cysteine (NAC) for Healing of Amputation Stumps in the Setting of Diabetes [EARLY_Phase 1]
Early-phase trial evaluating N-Acetyl-Cysteine for healing amputation stumps in diabetes; study completed with results posted.
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: The Endovascular Plus GENe Therapy Versus Only EndoVascular Therapy for Severe Limb ischaemiA Trial [Phase 4]
Phase 4 trial evaluating the addition of a gene therapy to endovascular treatment for severe limb ischemia; currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-07-31Clinical Trial Update: Platelet Activity in Vascular Surgery and Cardiovascular Events
A completed clinical trial from NYU Langone Health evaluating platelet activity in vascular surgery and its relation to cardiovascular event…
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CLINICAL_TRIALS trial_result · 2024-05-24Clinical Trial Update: SCOPE CLI (Shifting Care and Outcomes for Patients With Endangered Limbs - Critical Limb Ischemia)
Clinical trial update for the SCOPE CLI study on care shifting and outcomes for patients with critical limb ischemia; the trial status is co…
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CLINICAL_TRIALS trial_result · 2024-05-21Clinical Trial Update: PROMISE I Early Feasibility Trial of the LimFlow Stent Graft System [NA]
The PROMISE I early feasibility trial evaluated the LimFlow Stent Graft System for critical limb ischemia and chronic limb-threatening ische…
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CLINICAL_TRIALS trial_result · 2024-04-25Clinical Trial Update: Evaluation of Paclitaxel in Patients With CLI and Femoropopliteal Occlusive Disease Treated With DCB Angioplasty [NA]
This trial evaluates paclitaxel in patients with critical limb ischemia and femoropopliteal occlusive disease treated with drug-coated ballo…
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia [NA]
Clinical trial update for PROMISE II evaluating percutaneous deep vein arterialization in late-stage chronic limb-threatening ischemia; stat…
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CLINICAL_TRIALS trial_result · 2023-11-18Clinical Trial Update: ACP-01 in Patients With Critical Limb Ischemia [Phase 2]
Phase 2 trial update for ACP-01 in patients with critical limb ischemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: The DES BTK Vascular Stent System vs PTA in Subjects With Critical Limb Ischemia [Phase 3]
Phase 3 trial comparing the DES BTK Vascular Stent System to percutaneous transluminal angioplasty in critical limb ischemia has completed a…
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CLINICAL_TRIALS trial_result · 2023-04-24Clinical Trial Update: Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure [Phase 2]
A Phase 2 safety study of UT-15C SR (oral treprostinil) in patients undergoing a lower limb endovascular procedure for critical limb ischemi…
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CLINICAL_TRIALS trial_result · 2023-03-16Clinical Trial Update: The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM [Phase 3]
Phase 3 trial evaluating REX-001 for ischemic ulcers in patients with Critical Limb Ischemia (CLI) and diabetes was terminated.
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CLINICAL_TRIALS trial_result · 2021-09-02Clinical Trial Update: TEsting for Arterial Disease in Diabetes (TrEAD) Study
A completed clinical trial investigating arterial disease in diabetes (TrEAD) with results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Drug Eluting Balloon Angioplasty Versus Nitinol Stent Implantation in the Superficial Femoral Artery [Phase 4]
Phase 4 trial comparing drug-eluting balloon angioplasty with nitinol stent implantation in the superficial femoral artery for peripheral ar…