Colorectal Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-04-20Clinical Trial Update: Pembrolizumab and Disitamab Vedotin in HER2-expressing Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial update investigating pembrolizumab and disitamab vedotin in HER2-expressing metastatic colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-03-31Clinical Trial Update: Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC [Phase 2]
Phase 2 trial evaluating radiotherapy in combination with sintilimab, GM-CSF, and fruquintinib in patients with metastatic microsatellite-st…
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CLINICAL_TRIALS trial_result · 2022-02-23Clinical Trial Update: Neoadjuvant Chemoradiotherapy Plus Tislelizumab Followed by TME for LARC. [Phase 2]
Phase 2 trial update examining neoadjuvant chemoradiotherapy plus tislelizumab followed by total mesorectal excision for locally advanced re…
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CLINICAL_TRIALS trial_result · 2022-01-12Clinical Trial Update: Combination of Cetuximab, Capecitabine, and Oxaliplatin With or Without Bevacizumab [Phase 2]
Phase 2 trial of cetuximab, capecitabine, and oxaliplatin with or without bevacizumab in colorectal neoplasms was terminated; results posted…
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Effect of Jianpi Huatan Decoction on Advanced Colorectal Cancer [Phase 3]
Phase 3 trial update on Jianpi Huatan Decoction for advanced colorectal cancer is reported, with status currently unknown.
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CLINICAL_TRIALS trial_result · 2022-01-11Clinical Trial Update: Capecitabine and 131I-huA33 in Patients With Metastatic Colorectal Cancer [Phase 1]
Phase 1 clinical trial update of capecitabine combined with 131I-huA33 in metastatic colorectal cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: Standard of Care Alone or in Combination With Ad-CEA Vaccine and Avelumab in People With Previously Untreated Metastatic Colorectal Cancer QUILT-2.004 [Phase 2]
Phase 2 trial update evaluating standard of care with or without Ad-CEA vaccine and avelumab in previously untreated metastatic colorectal c…
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EMA withdrawal · 2021-11-25EMA Withdrawn: Equidacent (bevacizumab) — Centus Biotherapeutics Europe Limited
Equidacent (bevacizumab) has been withdrawn from the market in the European Medicines Agency record.
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CLINICAL_TRIALS trial_result · 2021-10-26Clinical Trial Update: A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination With Immune Checkpoint Inhibition in Refractory Colorectal Cancer [Phase 1, Phase 2]
Phase I/II trial investigating Pexa-Vec oncolytic virus in combination with immune checkpoint inhibitor for refractory colorectal cancer has…
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CLINICAL_TRIALS trial_result · 2021-09-16Clinical Trial Update: Adjuvant HIPEC in High Risk Colon Cancer [Phase 3]
Phase 3 trial evaluating adjuvant HIPEC for high-risk colon cancer has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-19Clinical Trial Update: Safety Study of 90Y-hMN14 to Treat Colorectal Cancer [Phase 1, Phase 2]
Clinical trial update for safety study of 90Y-hMN14 in colorectal cancer (Phase 1/Phase 2) completed.
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CLINICAL_TRIALS trial_result · 2021-07-20Clinical Trial Update: TAS-OX for Refractory Metastatic Colon Cancer [Phase 1, Phase 2]
Clinical trial update for TAS-OX in refractory metastatic colon cancer (colorectal neoplasms) across Phase 1 and Phase 2; results posted aft…
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Internet-Based Motivational Interviewing for Colonoscopy [NA]
A completed clinical trial evaluating internet-based motivational interviewing for colonoscopy related to colorectal neoplasms, with results…
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CLINICAL_TRIALS trial_result · 2021-07-02Clinical Trial Update: Multicenter Study Of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection In Patients With Advanced Colorectal Cancer [Phase 2]
Phase 2 multicenter trial of CPX-1 (Irinotecan HCl: Floxuridine) Liposome Injection in advanced colorectal cancer completed; results posted.
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CLINICAL_TRIALS trial_result · 2021-06-21Clinical Trial Update: FOLFIRI + Panitumumab First-line Treatment in Elderly Patients With Unresectable Metastatic Colorectal Cancer, RAS/BRAF Wild-type and Good Performance Status [Phase 2]
A Phase 2 trial evaluating first-line FOLFIRI plus panitumumab in elderly patients with unresectable metastatic colorectal cancer that is RA…
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CLINICAL_TRIALS trial_result · 2021-02-12Clinical Trial Update: Study of MK-1697 in Participants With Advanced Solid Tumors (MK-1697-001) [Phase 1]
Phase 1 study of MK-1697 in advanced solid tumors has been terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2020-09-17Clinical Trial Update: Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT) [Phase 2, Phase 3]
Clinical trial update for PUMP-IT combining hepatic arterial infusion pump chemotherapy with systemic chemotherapy in colorectal neoplasms (…
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CLINICAL_TRIALS trial_result · 2020-02-10Clinical Trial Update: Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer. [Phase 3]
Phase 3 trial comparing oxaliplatin/5-FU/leucovorin with versus without vatalanib in metastatic colorectal cancer completed.
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CLINICAL_TRIALS trial_result · 2020-01-14Clinical Trial Update: Apatinib in Refractory Colorectal Cancer [Phase 2]
Phase 2 trial update for apatinib in refractory colorectal cancer (colorectal neoplasms) completed.
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CLINICAL_TRIALS trial_result · 2019-12-27Clinical Trial Update: A Study of LY3009120 in Participants With Advanced Cancer or Cancer That Has Spread to Other Parts of Their Body [Phase 1]
Phase 1 trial of LY3009120 in advanced/metastatic cancer was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-11-04Clinical Trial Update: A Trial of Preoperative CHO Drinks on Postoperative Walking Capacity in Colorectal Surgery [NA]
A completed clinical trial evaluated preoperative carbohydrate drinks for post-operative walking capacity after colorectal surgery, with res…
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CLINICAL_TRIALS research · 2019-10-17Clinical Trial Update: Assessing a Endoscopic Mucosal Resection Site Using Different Endoscopic Imaging Methods [NA]
Clinical trial evaluating imaging methods to assess endoscopic mucosal resection sites in the colon.
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CLINICAL_TRIALS trial_result · 2019-10-15Clinical Trial Update: PIPAC for Peritoneal Metastases of Colorectal Cancer [Phase 2]
Phase 2 clinical trial update for PIPAC (pressurized intraperitoneal aerosol chemotherapy) in peritoneal metastases from colorectal cancer, …
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CLINICAL_TRIALS trial_result · 2019-09-23Clinical Trial Update: A Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer [Phase 1]
Phase I imaging and pharmacodynamic trial of CS-1008 in metastatic colorectal cancer has completed; results posted.
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CLINICAL_TRIALS trial_result · 2019-06-05Clinical Trial Update: Perioperative FOLFIRI VS Adjuvant FOLFIRI in Resectable Advanced CRC Failed to Oxaliplatin [Phase 3]
Phase 3 trial comparing perioperative FOLFIRI to adjuvant FOLFIRI in resectable advanced colorectal cancer after oxaliplatin failure; status…