Colorectal Neoplasms
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Demonstrating Effective Salvage of Inadequate Colonoscopies [NA]
Terminated clinical trial evaluating the salvage of inadequate colonoscopies using Motus GI technology in colorectal screening. The availabl…
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CLINICAL_TRIALS research · 2024-05-10Clinical Trial Update: Robotic Right Hemicolectomy Versus Laparoscopic Right Hemicolectomy [NA]
Clinical trial update indicating a study comparing robotic versus laparoscopic right hemicolectomy is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2024-04-26Clinical Trial Update: ENDO-AID Assisted Tandem Colonoscopy RCT [NA]
The ENDO-AID assisted tandem colonoscopy randomized controlled trial has completed.
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CLINICAL_TRIALS trial_result · 2024-04-24Clinical Trial Update: Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer [Phase 3]
Phase 3 clinical trial investigating SGM-101 for delineating primary, recurrent tumors and metastases in colorectal cancer surgery.
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EMA approval · 2024-04-05EMA Authorised: Lonsurf (trifluridine;tipiracil hydrochloride) — Les Laboratoires Servier
EMA authorised Lonsurf (trifluridine and tipiracil) for colorectal neoplasms; decision dated 26/07/2023.
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Treatment of Colorectal Liver Metastases With Immunotherapy and Bevacizumab [Phase 2]
Phase 2 trial investigating immunotherapy plus bevacizumab for colorectal liver metastases has completed.
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CLINICAL_TRIALS trial_result · 2024-01-30Clinical Trial Update: Perioperative Chemotherapy With Bevacizumab for Colorectal Carcinomatosis [Phase 2]
Phase 2 clinical trial update on perioperative chemotherapy with bevacizumab for colorectal carcinomatosis has completed.
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CLINICAL_TRIALS trial_result · 2024-01-29Clinical Trial Update: Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer [Phase 3]
A Phase 3 clinical trial is investigating the impact of other oncogene mutations on anti-EGFR efficacy in left-sided RAS-wild type metastati…
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CLINICAL_TRIALS trial_result · 2023-11-13Clinical Trial Update: A Randomized Clinical Trial of Shenbai Granules in Reducing Recurrence of Colorectal Adenoma [Phase 2, Phase 3]
Phase 2/3 randomized trial evaluating Shenbai Granules for reducing recurrence of colorectal adenoma; study completed.
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CLINICAL_TRIALS trial_result · 2023-10-11Clinical Trial Update: Brazilian Total Neoadjuvant Therapy Trial [Phase 3]
Clinical trial update for a Phase 3 Brazilian total neoadjuvant therapy trial in colorectal neoplasms.
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CLINICAL_TRIALS trial_result · 2023-08-07Clinical Trial Update: A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors [Phase 2]
Phase 2 trial evaluating alectinib for locally-advanced or metastatic ALK-positive solid tumors; study terminated with posted results.
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer [Phase 3]
A Phase 3 trial evaluating intravenous vitamin C in combination with chemotherapy in advanced colorectal cancer has completed.
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CLINICAL_TRIALS trial_result · 2023-01-19Clinical Trial Update: Ultrasound-enhanced Delivery of Chemotherapy to Patients With Liver Metastasis From Breast- and Colorectal Cancer [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating ultrasound-assisted delivery of chemotherapy for liver metastases from breast and colorectal cancer ha…
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CLINICAL_TRIALS trial_result · 2023-01-17Clinical Trial Update: Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy for Unresectable Colorectal Metastases/Intrahepatic Cholangiocarcinoma [NA]
Clinical trial update for Codman Catheter/Synchromed Pump Hepatic Artery Chemotherapy in unresectable colorectal metastases and intrahepatic…
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CLINICAL_TRIALS trial_result · 2022-12-22Clinical Trial Update: Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE) [Phase 2]
Phase 2 study evaluating tepotinib with cetuximab in left-sided RAS/BRAF wild-type metastatic colorectal cancer was terminated; results post…
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CLINICAL_TRIALS trial_result · 2022-12-14Clinical Trial Update: Cancer and Anesthesia: Survival After Radical Surgery - a Comparison Between Propofol or Sevoflurane Anesthesia [Phase 4]
Phase 4 trial comparing propofol versus sevoflurane anesthesia on survival after radical surgery for breast, colon, and rectal neoplasms.
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CLINICAL_TRIALS trial_result · 2022-11-17Clinical Trial Update: Mechanical Bowel Preparation and Oral Antibiotics Versus Mechanical Bowel Preparation Only Prior Rectal Surgery [Phase 4]
Phase 4 clinical trial evaluating mechanical bowel preparation with oral antibiotics versus mechanical bowel preparation alone prior to rect…
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CLINICAL_TRIALS trial_result · 2022-11-09Clinical Trial Update: Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line [Phase 2]
Phase 2 trial investigating surufatinib with or without immunotherapy for advanced colorectal cancer in later-line settings.
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CLINICAL_TRIALS trial_result · 2022-10-19Clinical Trial Update: Evaluation of the Safety and Efficacy of Esperanza Extract (PA001) [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and efficacy of Esperanza Extract (PA001) for various neoplastic conditions; current status i…
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CLINICAL_TRIALS trial_result · 2022-09-28Clinical Trial Update: PIPAC for the Treatment of Colorectal Peritoneal Metastases [Phase 1, Phase 2]
Phase 1/2 clinical trial investigating PIPAC for treating colorectal peritoneal metastases conducted by Imperial College London.
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CLINICAL_TRIALS trial_result · 2022-08-02Clinical Trial Update: Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer [Phase 2]
Phase 2 trial evaluating pemetrexed and TAS-102 in combination with bevacizumab for refractory colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-06-29Clinical Trial Update: Regorafenib Plus Raltitrexed as Third-line Treatment in Advanced Colorectal Cancer Patients [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating regorafenib in combination with raltitrexed as a third-line treatment for advanced colorectal cancer.
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CLINICAL_TRIALS trial_result · 2022-06-14Clinical Trial Update: New Adjuvant Chemotherapy of Asymptomatic Resectable Primary Lesion With Unresectable Liver-limited Metastases [Phase 3]
A Phase 3 trial assessed new adjuvant chemotherapy for patients with asymptomatic resectable primary colorectal tumors and unresectable live…
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CLINICAL_TRIALS trial_result · 2022-04-29Clinical Trial Update: Preoperative Systemic Therapy for Colorectal Cancer Peritoneal Metastases [Phase 2]
Phase 2 trial update on preoperative systemic therapy for colorectal cancer with peritoneal metastases.
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CLINICAL_TRIALS trial_result · 2022-04-26Clinical Trial Update: Preoperative Oral Antibiotics With vs Without Mechanical Bowel Preparation to Reduce Surgical Site Infections Following Colonic Resection: an International Randomized Controlled Trial. [Phase 4]
Phase 4 randomized trial evaluating preoperative oral antibiotics with versus without mechanical bowel preparation to reduce surgical site i…