Colorectal Neoplasms

• CLINICAL_TRIALS trial_result · 2026-08-26
  Clinical Trial Results: A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer [Phase 3]

  Phase 3 trial comparing nivolumab-relatlimab fixed-dose combination against regorafenib or TAS-102 in later-line metastatic colorectal cance…

• CLINICAL_TRIALS trial_result · 2026-07-13
  Clinical Trial Results: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]

  Phase 1/2 trial results for TC-510 in advanced mesothelin-expressing cancers were terminated with posted results.

• CLINICAL_TRIALS trial_result · 2026-04-22
  Clinical Trial Update: Combination of Artificial Intelligence and Mucosal Exposure Device to Enhance Colorectal Neoplasia Detection [NA]

  A completed clinical trial evaluated combining artificial intelligence with a mucosal exposure device to enhance detection of colorectal neo…

• CLINICAL_TRIALS trial_result · 2026-04-20
  Clinical Trial Update: A Study of PF-08046049/SGN-BB228 in Advanced Melanoma and Other Solid Tumors [Phase 1]

  This clinical trial update describes a Phase 1 study of PF-08046049/SGN-BB228 in advanced melanoma and other solid tumors, with the conditio…

• CLINICAL_TRIALS trial_result · 2026-04-02
  Clinical Trial Update: Perioperative Hemodynamic Optimization Using the Photoplethysmography in Colorectal Surgery [Phase 3]

  A completed Phase 3 trial evaluating perioperative hemodynamic optimization using photoplethysmography in colorectal surgery, sponsored by U…

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• CLINICAL_TRIALS trial_result · 2026-03-24
  Clinical Trial Update: A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor [Phase 1, Phase 2]

  This entry provides a status update on a phase 1/2 study of Eisai's E7386 in combination with other anticancer drugs for solid tumors. The t…

• CLINICAL_TRIALS trial_result · 2026-03-12
  Clinical Trial Update: The Long-term Effect of Artificial Intelligence-assisted Colonoscopy on Risk of Metachronous Advanced Colonic Lesion [NA]

  This clinical trial assesses whether AI-assisted colonoscopy reduces the long-term risk of metachronous advanced colonic lesions in patients…

• CLINICAL_TRIALS trial_result · 2026-03-06
  Clinical Trial Update: A Patient Blinded, Randomized, Controlled Trial Comparing Right Colon Adenoma Detection Rate in Colonoscopy Using Right Colon Water Exchange and Traditional Air Insufflation [NA]

  The trial reports the completion of a blinded, randomized comparison of right colon water exchange versus traditional air insufflation for r…

• CLINICAL_TRIALS trial_result · 2026-02-10
  Clinical Trial Update: Effect of Blink-Based Training on Cancer Detection in Colorectal Polyp Images by Medical Students/Non GI-trainees [NA]

  This completed clinical trial evaluated whether blink-based training improves cancer detection in colorectal polyp images among medical stud…

• CLINICAL_TRIALS trial_result · 2025-12-24
  Clinical Trial Update: Risk of Metachronous Advanced Colorectal Neoplastic Among Individuals With Varying Numbers of Non-Advanced Adenomas Detected During Screening Colonoscopy

  This completed clinical trial investigated the risk of metachronous advanced colorectal neoplasia among individuals with varying numbers of …

• CLINICAL_TRIALS trial_result · 2025-12-09
  Clinical Trial Update: Real-time Artificial Intelligence-based Endocytoscopic Diagnosis of Colorectal Neoplasms

  This update reports the completion of a clinical trial evaluating a real-time AI endocytoscopic diagnostic tool for colorectal neoplasms.

• CLINICAL_TRIALS trial_result · 2025-11-24
  Clinical Trial Update: DETERMINE Trial Treatment Arm 02: Atezolizumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With High Tumour Mutational Burden (TMB) or Microsatellite Instability-high (MSI-high) or Proven Constitutional Mismatch Repair Deficiency (CMMRD) Disposition [Phase 2, Phase 3]

  The update notes ongoing recruitment for the DETERMINE trial Arm 02 investigating atezolizumab in adults and pediatric/young adult patients …

• CLINICAL_TRIALS trial_result · 2025-10-24
  Clinical Trial Update: A Study of E7386 in Combination With Pembrolizumab in Previously Treated Participants With Selected Solid Tumors [Phase 1, Phase 2]

  Results from a Phase 1/2 study of E7386 in combination with pembrolizumab in previously treated solid tumors (melanoma, hepatocellular carci…

• CLINICAL_TRIALS trial_result · 2025-10-14
  Clinical Trial Update: Computer Assisted Detection of Neoplasia During Colonoscopy Evaluation

  A clinical trial evaluating computer assisted detection of neoplasia during colonoscopy has completed, sponsored by the VA Puget Sound Healt…

• CLINICAL_TRIALS trial_result · 2025-10-02
  Clinical Trial Update: Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions

  This completed clinical trial evaluated diagnostic accuracy for predicting the histology of colorectal lesions. It compared different diagno…

• CLINICAL_TRIALS trial_result · 2025-09-12
  Clinical Trial Update: A Study of NUC-3373 in Combination With Other Agents in Patients With Colorectal Cancer [Phase 2]

  Phase 2 trial update for NUC-3373 in combination with other agents in colorectal cancer; the study was terminated and results have been post…

• CLINICAL_TRIALS trial_result · 2025-08-15
  Clinical Trial Update: The Influence of Artificial Intelligence (AI )Assisted Polyp Detection (Discovery System) on Visual Gaze Patterns During Real-time Colonoscopy

  A completed clinical trial evaluated how an AI-assisted polyp detection system affects visual gaze patterns during real-time colonoscopy.

• CLINICAL_TRIALS trial_result · 2025-08-15
  Clinical Trial Update: A Study Comparing Standard and AI-Assisted Colonoscopies for Detecting and Characterizing Colorectal Lesions in Adults Aged 50-74 Undergoing Cancer Screening [NA]

  A completed clinical trial comparing standard versus AI-assisted colonoscopy for detecting and characterizing colorectal lesions in adults 5…

• CLINICAL_TRIALS trial_result · 2025-07-30
  Clinical Trial Update: Combination Immunotherapy in Colorectal Cancer [Phase 2]

  A Phase 2 trial of combination immunotherapy in colorectal cancer has been suspended.

• CLINICAL_TRIALS trial_result · 2025-07-24
  Clinical Trial Update: Artificial Intelligence Aid Systems and Endocuff in Colorectal Adenoma Detection [NA]

  A completed clinical trial evaluating AI-assisted colonoscopy systems and Endocuff to improve adenoma detection rate during colorectal scree…

• CLINICAL_TRIALS trial_result · 2025-06-17
  Clinical Trial Update: HAIP Combined With Fuquinitinib as Late-line Treatment in Patients With CRLM：A Phase 2 Single-Arm Clinical Trial [Phase 2]

  Phase 2 single-arm trial evaluating Fuquinitinib in combination with hepatic artery infusion for late-line treatment of colorectal neoplasms…

• CLINICAL_TRIALS trial_result · 2025-06-15
  Clinical Trial Update: Incomplete Follow Up After Positive FIT or Stool DNA Testing: A Multimethod Approach [NA]

  This clinical trial update highlights incomplete follow-up after a positive FIT or stool DNA test in colorectal cancer screening. The study …

• CLINICAL_TRIALS trial_result · 2025-05-23
  Clinical Trial Update: Optimisation and Performance of Reduced Preparation CT Colography [Phase 4]

  An update on a Phase 4 clinical trial evaluating optimized, reduced-preparation CT colonography performance in patients at risk for colorect…

• CLINICAL_TRIALS trial_result · 2025-05-14
  Clinical Trial Update: Diagnostic Value of Endocytoscopy for Colorectal Lesions

  A completed clinical trial evaluated the diagnostic value of endocytoscopy for diagnosing colorectal lesions.

• CLINICAL_TRIALS trial_result · 2025-05-02
  Clinical Trial Update: Suturing Through-the-scope System Used for Prophylactic Closure of Colonic Post-ESD Defects [NA]

  A clinical trial update describes the use of a through-the-scope suturing system to prophylactically close colonic defects after endoscopic …