Colorectal Liver Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases
Clinical trial update about SMYD3-driven metabolic changes in colorectal cancer with liver metastases; trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis [EARLY_Phase 1]
Pilot Phase 1 study evaluating an implantable microdevice to assess in situ drug response in patients with colorectal liver metastases (meta…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases [Phase 2]
A Phase 2 clinical trial is investigating ctDNA-directed post-hepatectomy chemotherapy for patients with resectable colorectal liver metasta…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI [Phase 3]
Phase 3 trial evaluating adjuvant FOLFIRI-based chemotherapy after resection of colorectal liver metastases that responded to preoperative F…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM [Phase 2]
Phase 2 clinical trial evaluating a combination therapy including the oncolytic virus H101 with SBRT, chemotherapy, targeted therapy, and im…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response [NA]
An ongoing clinical trial at MD Anderson is evaluating an advanced MRI diffusion technique (Intravoxel Incoherent Motion) to evaluate treatm…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases [Phase 2, Phase 3]
This document notes a Phase 2/3 clinical trial examining IP-001 injected into thermally ablated hepatic tumors in patients with colorectal l…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Feasibility of Circulating Tumour DNA (ctDNA) Analysis Using Automated Capillary Blood Sampling
This trial assesses the feasibility of monitoring circulating tumor DNA using automated capillary blood sampling in colorectal cancer, inclu…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases [Phase 1]
A Phase 1 trial evaluating preoperative yttrium-90 radioembolization to control colorectal liver metastases and promote future liver remnant…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Paclitaxel Cationic Liposome (Hepatic Arterial Infusion) in Combination With Systemic Therapy as First-Line Treatment in Colorectal Liver Metastases [Phase 1]
Phase 1 clinical trial evaluating paclitaxel cationic liposome delivered via hepatic arterial infusion in combination with systemic therapy …
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Efficacy and Safety of DEB-TACE Combined With HAIC Versus HAIC Alone in Patients With Unresectable CRLM
A planned clinical trial comparing DEB-TACE combined with hepatic artery infusion chemotherapy (HAIC) versus HAIC alone for unresectable col…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients [Phase 2]
A Phase 2 trial comparing hepatic arterial infusion FOLFOX plus irinotecan with or without bevacizumab to systemic FOLFOXIRI with or without…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Evaluation of Efficacy and Safety of PD-1 Monoclonal Antibody in Combination With rhG-CSF, IL-2, and CapeOX in Initially Resectable Synchronous Colorectal Liver Metastases
A clinical trial update evaluating a PD-1 monoclonal antibody in combination with rhG-CSF, IL-2, and CapeOX for initially resectable synchro…
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CLINICAL_TRIALS research · 2009-12-18Clinical Trial Update: Compare FOFLOX4 in Preoperative and Postoperative and Postoperative in Resectable Liver Metastasis Colorectal Cancer (MCC) [Phase 3]
A Phase 3 trial evaluating FOFLOX4 for resectable colorectal liver metastases in colorectal cancer. Current trial status is unknown.