Colorectal Liver Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases
Clinical trial update about SMYD3-driven metabolic changes in colorectal cancer with liver metastases; trial status is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-27Clinical Trial Update: Pilot Study of an Implantable Microdevice for In Situ Evaluation of Drug Response in Patients With Colorectal Liver Metastasis [EARLY_Phase 1]
Pilot Phase 1 study evaluating an implantable microdevice to assess in situ drug response in patients with colorectal liver metastases (meta…
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CLINICAL_TRIALS research · 2026-02-06Clinical Trial Update: ctDNA-Directed Post-Hepatectomy Chemotherapy for Patients With Resectable Colorectal Liver Metastases [Phase 2]
A Phase 2 clinical trial is investigating ctDNA-directed post-hepatectomy chemotherapy for patients with resectable colorectal liver metasta…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI [Phase 3]
Phase 3 trial evaluating adjuvant FOLFIRI-based chemotherapy after resection of colorectal liver metastases that responded to preoperative F…
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CLINICAL_TRIALS research · 2026-02-02Clinical Trial Update: Oncolytic Virus (H101) + SBRT + Chemotherapy + Targeted Therapy + Immunotherapy for Unresectable CRLM [Phase 2]
Phase 2 clinical trial evaluating a combination therapy including the oncolytic virus H101 with SBRT, chemotherapy, targeted therapy, and im…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: An Investigational Scan (Intravoxel Incoherent Motion Diffusion Weighted Imaging) for the Evaluation of Colorectal Cancer Liver Metastases Treatment Response [NA]
An ongoing clinical trial at MD Anderson is evaluating an advanced MRI diffusion technique (Intravoxel Incoherent Motion) to evaluate treatm…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases [Phase 2, Phase 3]
This document notes a Phase 2/3 clinical trial examining IP-001 injected into thermally ablated hepatic tumors in patients with colorectal l…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Feasibility of Circulating Tumour DNA (ctDNA) Analysis Using Automated Capillary Blood Sampling
This trial assesses the feasibility of monitoring circulating tumor DNA using automated capillary blood sampling in colorectal cancer, inclu…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases [Phase 1]
A Phase 1 trial evaluating preoperative yttrium-90 radioembolization to control colorectal liver metastases and promote future liver remnant…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: Paclitaxel Cationic Liposome (Hepatic Arterial Infusion) in Combination With Systemic Therapy as First-Line Treatment in Colorectal Liver Metastases [Phase 1]
Phase 1 clinical trial evaluating paclitaxel cationic liposome delivered via hepatic arterial infusion in combination with systemic therapy …
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Efficacy and Safety of DEB-TACE Combined With HAIC Versus HAIC Alone in Patients With Unresectable CRLM
A planned clinical trial comparing DEB-TACE combined with hepatic artery infusion chemotherapy (HAIC) versus HAIC alone for unresectable col…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: FOLFOX Via HAI Plus Intravenous Irinotecan With or Without Bevacizumab Versus Systemic FOLFOXIRI With or Without Bevacizumab in Initially Unresectable RAS-mutated CRLM Patients [Phase 2]
A Phase 2 trial comparing hepatic arterial infusion FOLFOX plus irinotecan with or without bevacizumab to systemic FOLFOXIRI with or without…
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CLINICAL_TRIALS trial_result · 2024-07-30Clinical Trial Update: Patient Outcomes After Hepatic Artery Infusion Pump Placement
This clinical trial update reports patient outcomes after hepatic artery infusion pump placement in patients with colorectal cancer and colo…
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CLINICAL_TRIALS research · 2024-07-17Clinical Trial Update: Evaluation of Efficacy and Safety of PD-1 Monoclonal Antibody in Combination With rhG-CSF, IL-2, and CapeOX in Initially Resectable Synchronous Colorectal Liver Metastases
A clinical trial update evaluating a PD-1 monoclonal antibody in combination with rhG-CSF, IL-2, and CapeOX for initially resectable synchro…
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CLINICAL_TRIALS other · 2024-06-13Clinical Trial Update: Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer [NA]
A clinical trial update indicates an anatomical resection approach for liver metastases in patients with RAS-mutated colorectal cancer is cu…
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CLINICAL_TRIALS trial_result · 2024-01-17Clinical Trial Update: Fruquintinib Combined With Tislelizumab and HAIC in Patients With Advanced Colorectal Liver Metastases Cancer Who Failed Standard Therapy [Phase 2]
Phase 2 clinical trial update investigating fruquintinib combined with tislelizumab and hepatic arterial infusion chemotherapy (HAIC) in adv…
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CLINICAL_TRIALS trial_result · 2023-05-26Clinical Trial Update: The Safety and Efficacy of HAIC+Tislelizumab+Regorafenib in Patients With Colorectal Liver Metastases [Phase 2]
Phase 2 clinical trial evaluating HAIC + tislelizumab + regorafenib for colorectal liver metastases is underway, with status currently unkno…
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CLINICAL_TRIALS trial_result · 2023-03-20Clinical Trial Update: Quintuple Method for Treatment of Multiple Refractory Colorectal Liver Metastases [Phase 2]
A Phase 2 clinical trial update investigating a quintuple treatment method for patients with colorectal liver metastases who cannot undergo …
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CLINICAL_TRIALS trial_result · 2023-01-30Clinical Trial Update: Yttrium-90 Carbon Microspheres in Patients With Unresectable Colorectal Liver Metastases [Phase 1, Phase 2]
Clinical trial update for Yttrium-90 carbon microspheres in unresectable colorectal liver metastases (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2022-12-20Clinical Trial Update: Efficacy of Irreversible Electroporation (IRE) for Central Colorectal Liver Metastases [Phase 2]
Phase 2 clinical trial update evaluating the efficacy of irreversible electroporation (IRE) for central colorectal liver metastases.
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CLINICAL_TRIALS trial_result · 2019-09-11Clinical Trial Update: Cetuximab/FOLFIRI With or Without Oxaliplatin and FOLFOXIRI With or Without Bevacizumab in Neoadjuvant Treatment of Non-resectable Colorectal Liver Metastases [Phase 2]
Phase 2 trial evaluating Cetuximab/FOLFIRI with or without Oxaliplatin, and FOLFOXIRI with or without Bevacizumab for neoadjuvant treatment …
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CLINICAL_TRIALS trial_result · 2016-10-25Clinical Trial Update: Impact of Pre-operative Bevacizumab on Complications After Resection of Colorectal Liver Metastases
A clinical trial assessing whether pre-operative bevacizumab influences complications after surgical resection of colorectal liver metastase…
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CLINICAL_TRIALS trial_result · 2015-03-30Clinical Trial Update: Health Related Quality of Life After Surgery and Oncological Treatment of Colorectal Liver Metastases
This trial update reports on health-related quality of life outcomes after surgery and oncological treatment for patients with colorectal li…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Multiple Minor Hepatectomies Versus Major or Extended Hepatectomies for Colorectal Liver Metastases.
Clinical trial update on a completed study comparing minor liver resections to major or extended hepatectomies for colorectal liver metastas…
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CLINICAL_TRIALS trial_result · 2012-07-03Clinical Trial Update: Minimally Invasive Liver Surgery for Metastases From Colorectal Cancer: Oncologic Outcome and Prognostic Factors
Long-term oncologic outcomes and prognostic factors are reported for patients with colorectal liver metastases treated with minimally invasi…