Colorectal Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Prospective National Cohort Evaluating Predictive Biomarkers of Resistance to Immunotherapy in Patients With MSI/dMMR Metastatic Colorectal Cancer (CORESIM)
A prospective national cohort study investigating predictive biomarkers of resistance to immunotherapy in patients with metastatic colorecta…
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CLINICAL_TRIALS withdrawal · 2025-10-06Clinical Trial Update: CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer [Phase 2]
A Phase 2 trial evaluating CBX-12 for metastatic colorectal cancer that is mismatch repair proficient has been withdrawn, with no ongoing en…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers [NA]
A UCSF-led clinical trial is evaluating radiation therapy for metastatic gastrointestinal cancers, and the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: A Multi-center Investigation of Family Health.
Odense University Hospital is sponsoring a multi-center study on family health that is currently recruiting, with focus conditions including…
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CLINICAL_TRIALS research · 2025-10-06Clinical Trial Update: ONLOOP Trial: Evaluating a New Surveillance and Support System for Survivors of Childhood Cancer in Ontario [NA]
The ONLOOP trial is evaluating a new surveillance and support system for survivors of childhood cancer in Ontario; the study status is NOT_Y…
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CLINICAL_TRIALS trial_result · 2025-10-03Clinical Trial Update: Voyage: Real-World Impact of the Multi-target Stool DNA Test on CRC Screening and Mortality
Real-world data from the Voyage study evaluates the impact of Exact Sciences' multi-target stool DNA test on colorectal cancer screening and…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: D,L-MEthadone and mFOLFOX6 in Treatment of Advanced Colorectal Cancer [Phase 1, Phase 2]
A phase 1/phase 2 clinical trial evaluating D,L-Methadone in combination with mFOLFOX6 for advanced chemo-refractory colorectal cancer is cu…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Endoscopic Resection of Gastrointestinal Neoplasms
Clinical trial update indicating ongoing recruitment for endoscopic resection techniques (EMR and ESD) to treat gastrointestinal neoplasms.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Tovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid Tumors [Phase 2]
Phase 2 monotherapy trial of tovorafenib (DAY101) in melanoma and other solid tumors was terminated, with results posted.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB [Phase 3]
Phase 3 clinical trial in metastatic colorectal cancer comparing FOLFIRI plus cetuximab versus bevacizumab, using tissue RAS/BRAF wild-type …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Effects of Oxaliplatin-Induced Peripheral Neuropathy on Hand Function, Grip Strength and Quality of Life in Colorectal Cancer Patients
A clinical trial update examining how oxaliplatin-induced peripheral neuropathy affects hand function, grip strength, and quality of life in…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: The Phase 1b/IIa, Open-label, Dose Escalation and Dose Expansion to Evaluate Safety, Tolerability, and Preliminary Efficacy of the Combination of HCB101, Cetuximab/Bevacizumab, and FOLFOX/FOLFIRI in Advanced or Metastatic Colorectal Cancer [Phase 1, Phase 2]
Phase 1b/IIa open-label study evaluating safety, tolerability, and preliminary efficacy of combining HCB101 with Cetuximab or Bevacizumab pl…
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CLINICAL_TRIALS other · 2025-10-02Clinical Trial Update: Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors [Phase 1, Phase 2]
Clinical trial update for a phase 1/2 autologous and allogeneic whole cell cancer vaccine in metastatic tumors, currently recruiting across …
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/Phase 2 study evaluating LBL-007 in combination with tislelizumab plus bevacizumab and a fluoro…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: A Study of Irinotecan With Dabrafenib Plus Trametinib and Anti-EGFR in the Second Line of Therapy in People With Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial evaluating irinotecan combined with dabrafenib and trametinib, plus anti-EGFR, as second-line therapy for metastatic …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors [Phase 1]
This update covers a Phase 1 trial of a CAR-T therapy targeting carcinoembryonic antigen (CEA) for CEA-positive advanced solid tumors, curre…
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Trial of Atezolizumab, Bevacizumab, and Tiragolumab in Patients With Microsatellite Stable, Metastatic Colorectal Cancer [Phase 2]
Phase 2 clinical trial update of atezolizumab, bevacizumab, and tiragolumab for microsatellite stable metastatic colorectal cancer; the stud…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: This Study Has Been Designed to Support the Working Hypothesis That Emergency Surgery in a Colon Obstruction Neoplasm is Better Than Stent Bridge Due to Better Oncological Outcomes, Analyzing the Importance of ERAS Programs in Emergency Colon Obstruction Surgery.
This study protocol aims to compare emergency surgery with stent bridging for colon obstruction due to neoplasm and to evaluate the role of …
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Care for Colon 2015 [NA]
Care for Colon 2015, sponsored by Odense University Hospital, concerns colorectal cancer and colorectal adenoma and has completed the study.
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Circulating DNA to Improve Outcome of Oncology PatiEnt. A Randomized Study [NA]
A randomized trial evaluating circulating DNA to improve outcomes in oncology is currently recruiting for colorectal cancer and non-small ce…
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CLINICAL_TRIALS research · 2025-10-02Clinical Trial Update: Exploring Participant Preference for Screening Methods and Experience Into Colorectal Cancer Screening Programme [NA]
A recruiting clinical trial by Advanced Marker Discovery S.L. studying participant preferences and experiences with colorectal cancer screen…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Neoadjuvant Encorafenib, Binimetinib and Cetuximab for Patients With BRAF V600E Mutated/pMMR Localized Colorectal Cancer [Phase 2]
A Phase 2 neoadjuvant trial is evaluating a triple combination of encorafenib, binimetinib, and cetuximab in patients with BRAF V600E-mutate…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Observational Cross-reactivity Study for Colorectal Cancer Diagnosis
An observational cross-reactivity study evaluating diagnostic approaches for colorectal cancer is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Development and Validation of a Blood Test for Early Diagnosis of Colorectal Cancer
A recruiting study aims to develop and validate a blood-based test for early detection of colorectal cancer and advanced adenomas.
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: How Emotional Granularity Helps Build Resilience in Young and Middle-Aged Colorectal Cancer Survivors
This clinical trial investigates whether emotional granularity training can enhance resilience in young and middle-aged colorectal cancer su…