Colorectal Cancer with Liver Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: AK104 Plus Radiotherapy Combined With Standard Therapy Versus Standard Therapy as First-Line Treatment for pMMR/MSS CRLM (APSOC) [Phase 2]
Phase 2 study evaluating AK104 plus radiotherapy with standard therapy as first-line treatment for microsatellite-stable colorectal cancer w…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: Safety of HRX215 in Patients After Minor and Major Liver Resection [Phase 1, Phase 2]
Clinical trial update on the safety of HRX215 in patients after minor and major liver resection. The study is in Phase 1 and Phase 2 and is …
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CLINICAL_TRIALS other · 2026-04-09Clinical Trial Update: Botensilimab, Balstilimab, and SBRT in Colorectal Cancer [EARLY_Phase 1]
This clinical trial update describes an early-phase study evaluating botensilimab, balstilimab, and SBRT in non-MSI-H or pMMR colorectal can…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases [Phase 2]
This is a Phase 2 platform study update describing immunotherapy combination strategies for metastatic colorectal cancer with liver metastas…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Microwave Ablation Versus Stereotactic Body Radiotherapy for Colorectal Liver Metastases in Oligometastatic Disease: a Prospective, Randomised, Phase 2 Trial [Phase 2]
A Phase 2 randomized trial comparing microwave ablation to stereotactic body radiotherapy for colorectal cancer with liver metastases in oli…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Abemaciclib Combined With FOLFOX/FOLFIRI Regimen in Patients With Advanced Colorectal Liver Metastases Cancer [Phase 2]
A Phase 2 clinical trial is evaluating abemaciclib in combination with FOLFOX or FOLFIRI in patients with colorectal cancer that has metasta…
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CLINICAL_TRIALS research · 2026-02-25Clinical Trial Update: Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer [Phase 1]
Phase 1 trial evaluating combination chemotherapy and bevacizumab with the NovoTTF-100L(P) system for colorectal cancer with liver metastase…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Postoperative Exercise Training and Colorectal Cancer Liver Metastasis [NA]
A Danish clinical trial sponsored by Rigshospitalet is evaluating postoperative exercise training in patients with colorectal cancer and liv…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Yttrium-90 Radioembolization Neoadjuvant Therapy With Immune Marker Profiling and Dosimetry for Potentially Resectable Patients With Colorectal Liver Metastases
A clinical trial evaluating Yttrium-90 radioembolization as neoadjuvant therapy with immune marker profiling and dosimetry for potentially r…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
A Northwestern University-sponsored clinical trial is recruiting to evaluate an auxiliary liver transplantation approach with delayed resect…
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CLINICAL_TRIALS research · 2026-02-04Clinical Trial Update: The Use of Artificial Intelligence for the Prediction of Recurrence After Resection of Colorectal Liver Metastases
ClinicalTrials.gov study evaluating artificial intelligence methods to predict recurrence after resection of colorectal liver metastases; th…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Targeted Treatment Plus Tislelizumab and HAIC for Advanced CRCLM Failed From Standard Systemic Treatment [NA]
This clinical trial update notes an active-not-recruiting study evaluating a combination of targeted therapy with tislelizumab and hepatic a…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases
This clinical trial aims to evaluate exosome-derived liquid biopsy for detecting extrahepatic metastases in colorectal cancer patients with …
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Evaluation of the Efficacy of Two Guidance Techniques (Standard Injected CT vs Porto-scanner With Angio-CT) for Thermoablation Treatment of Colorectal Cancer Liver Metastases [NA]
A clinical trial evaluating two guidance techniques for thermoablation of colorectal cancer liver metastases has been terminated.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: A Study of AK112 in Combination With VG2025 in Colorectal Cancer With Liver Metastases [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating AK112 in combination with VG2025 for colorectal cancer with liver me…
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CLINICAL_TRIALS research · 2026-01-13Clinical Trial Update: Selective Internal Radiation Therapy With 90Y Resin Micropheres for Refractory Colorectal Cancer Liver Metastases
Clinical trial is recruiting to evaluate selective internal radiation therapy with yttrium-90 resin microspheres for colorectal cancer that …
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Liver-directed Chemotherapy After Surgery of Liver Metastases of Colorectal Cancer in Patients With High Risk of Recurrence of Their Disease [Phase 3]
Phase 3 clinical trial evaluating liver-directed chemotherapy after surgical resection of colorectal cancer liver metastases in patients at …
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Infusion System for Hepatic Cancer [NA]
An ongoing clinical trial is evaluating an infusion system for hepatic cancers, including colorectal cancer with liver metastases and intrah…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Liver Transplantation for Unresectable Liver Limited Colorectal Metastases
A clinical trial in recruitment evaluating liver transplantation for patients with unresectable liver-limited colorectal metastases.
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Comparison of the Resection Site Order in Simultaneous Approach of Colorectal Liver Metastasis
This clinical trial investigates the order of resection sites in a simultaneous surgical approach for colorectal liver metastases and is cur…
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: International Study on Treatment of Patients With Metastatic Colorectal Liver Lesions Patients With IRE [NA]
This entry describes an international clinical trial evaluating irreversible electroporation (IRE) for colorectal cancer metastasized to the…
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CLINICAL_TRIALS research · 2025-09-10Clinical Trial Update: Prospective Cohort Study on Thermal Ablation of Malignant Liver Tumors
Prospective cohort study assessing the use of thermal ablation for malignant liver tumors, currently recruiting at Leiden University Medical…
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors [NA]
Clinical trial update on multimodal thermal therapy for malignant liver tumors, evaluating safety, efficacy, and immune response in hepatoce…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: The Role of the Imaging FAPI PET/CT in Exploring the Microenvironment of Colorectal Cancer Liver Metastases [NA]
A clinical trial is evaluating the use of FAPI PET/CT imaging to study the tumor microenvironment in colorectal cancer that has metastasized…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: I-FIGS Feasibility Study [NA]
Clinical trial update indicating the completion of the I-FIGS feasibility study sponsored by University Hospital Plymouth NHS Trust. The stu…