Colorectal Cancer with Liver Metastases
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-31Clinical Trial Update: Aspirin in Colorectal Cancer Liver Metastases [Phase 2, Phase 3]
An Oslo University Hospital-sponsored trial is evaluating aspirin for colorectal cancer with liver metastases. The study spans Phase 2 and P…
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: On-treatment Biomarkers in Metastatic Colorectal Cancer for Life
A clinical trial update for NCT05755672 on on-treatment biomarkers in metastatic colorectal cancer. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
A clinical trial investigating living donor liver transplantation as a treatment for unresectable colorectal liver metastases; recruitment i…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
The document describes a clinical trial that uses comprehensive genomic profiling in colorectal cancer patients with isolated liver metastas…
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Fruquintinib Combined With Sintilimab ± Radiotherapy for Third-line Treatment of Colorectal Cancer With Liver Metastases [Phase 2]
A Phase 2 clinical trial update evaluating the combination of Fruquintinib and Sintilimab, with or without radiotherapy, as third-line thera…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Iparomlimab/Tuvonralimab Combined With Bevacizumab and CAPEOX as Conversion Therapy for Colorectal Cancer Liver Metastasis [Phase 2]
Phase 2 clinical trial update evaluating iparomlimab and tuvonralimab with Bevacizumab and CAPEOX as conversion therapy for colorectal cance…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis [Phase 2]
Phase 2 clinical trial evaluating FOLFOX-HAIC as conversion therapy to make initially unresectable colorectal liver metastases resectable. T…
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CLINICAL_TRIALS research · 2025-05-15Clinical Trial Update: A Prospective Multicenter Study: Ivosimab + Chemotherapy as Neoadjuvant for Resectable pMMR/MSS CRC Liver Mets [Phase 2]
A Phase 2 multicenter trial evaluating neoadjuvant therapy with Ivosimab plus chemotherapy for resectable colorectal cancer with liver metas…
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CLINICAL_TRIALS trial_result · 2025-05-06Clinical Trial Update: Effect of Surgical Margin Width on Recurrence and Survival in Patients With Hepatic Oligometastasis of Colorectal Cancer [NA]
A clinical trial evaluating whether the width of surgical margins influences recurrence and survival in patients with colorectal cancer that…
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CLINICAL_TRIALS research · 2025-04-17Clinical Trial Update: Laparoscopic Associating Liver Partition With Portal Vein Ligation for Staged Hepatectomy (ALPPS) for Colorectal Liver Metastases (CRLM)
Clinical trial update on laparoscopic ALPPS for colorectal cancer with liver metastases; the study is currently not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-04-11Clinical Trial Update: The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery
A completed clinical trial comparing laparoscopic hybrid surgery to totally open surgery for resection of resectable synchronous colorectal …
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Local Immunomodulation After Radiofrequency of Unresectable Colorectal Liver Metastases [Phase 1]
This document reports a Phase 1 clinical trial evaluating local immunomodulation following radiofrequency ablation for unresectable colorect…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery [NA]
A three-arm clinical trial called TANGO-LIVER is evaluating nuclear growth observation in liver surgery and is currently recruiting particip…
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CLINICAL_TRIALS trial_result · 2025-03-06Clinical Trial Update: Argipressin's Influence on Blood Loss During Hepatic Resection [Phase 4]
Phase 4 trial update evaluating Argipressin's effect on intraoperative blood loss during hepatic resection in colorectal cancer with liver m…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Cryoablation Combined with Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis [Phase 2]
This is a Phase 2 clinical trial evaluating cryoablation in combination with sintilimab and regorafenib for previously treated colorectal ca…
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CLINICAL_TRIALS research · 2025-01-23Clinical Trial Update: PULSAR Combined With PD-1 Ab and Chemotherapy Plus Bev. for CRLM [Phase 2]
A Phase 2 clinical trial is evaluating PULSAR in combination with a PD-1 inhibitor, chemotherapy, and bevacizumab for colorectal cancer with…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Simultaneous Portal and Hepatic Vein Versus Portal Vein Embolizations for Hypertrophy of the Future Liver Remnant [Phase 2]
Phase 2 clinical trial comparing simultaneous portal and hepatic vein embolization versus portal vein embolization to induce hypertrophy of …
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CLINICAL_TRIALS research · 2024-12-05Clinical Trial Update: Improving Survival of COlorectal LIver Metastases by RFA-mediated Immunostimulation [NA]
A clinical trial evaluating survival in colorectal cancer with liver metastases using radiofrequency ablation–mediated immunostimulation; re…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: Neoadjuvant Safety of Sintilimab + XELOX + Bevacizumab in PMMR/MSS CRLM Patients [Phase 1, Phase 2]
A phase 1/2 trial assessing the safety of combining sintilimab with XELOX (capecitabine + oxaliplatin) and bevacizumab as neoadjuvant therap…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
An observational registry study (SIRtain Registry) evaluating the use of SIR-Spheres Y-90 resin microspheres for unresectable liver tumors. …
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden. [Phase 2]
Phase 2 trial evaluating hepatic arterial infusion with floxuridine (Liver-Tx) plus second-line chemotherapy versus second-line chemotherapy…
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CLINICAL_TRIALS research · 2024-11-01Clinical Trial Update: The DRAGON 2 Trial [NA]
The DRAGON 2 trial, sponsored by Maastricht University, is currently recruiting for colorectal cancer with liver metastases, focusing on sma…
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases [NA]
This update covers a Swedish clinical trial evaluating liver transplantation for non-resectable colorectal cancer liver metastases.
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CLINICAL_TRIALS research · 2024-10-02Clinical Trial Update: Liver Transplantation for Non-resectable Colorectal Liver Metastases: Translational Research [NA]
Translational research study examining liver transplantation as a treatment option for non-resectable colorectal liver metastases.
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Study on the Efficacy and Safety of Multi-mode Ablation Combined With Systemic Therapy in the Treatment of CRCLM [Phase 2]
Phase 2 clinical trial evaluating multimodal ablation combined with systemic therapy for colorectal cancer with liver metastases; the study …