Cocaine Use Disorder
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: SXC-2023 Cocaine Interaction Study [Phase 1]
A Phase 1 trial update on the SXC-2023 Cocaine Interaction Study for Cocaine Use Disorder, with results posted on 2026-04-24.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Phase1, STP7 Cocaine Drug-Drug Interaction Study [Phase 1]
Phase 1 study STP7 evaluating potential drug-drug interaction with cocaine in individuals with Cocaine Use Disorder has completed.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Impact of Cocaine Use and Withdrawal on Sleep
A clinical trial update from Hôpital le Vinatier studying how cocaine use and withdrawal affect sleep in individuals with cocaine use disord…
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: The Role of Potassium Channels in Working Memory Impairments of Chronic Cocaine Users [NA]
A clinical trial is exploring the role of potassium channels in working memory impairments among individuals with Cocaine Use Disorder; the …
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CLINICAL_TRIALS trial_result · 2026-04-07Clinical Trial Update: Safety Profile of Psilocybin for Cocaine Use Disorder [EARLY_Phase 1]
This update reports on the safety profile of psilocybin in an early-phase trial for cocaine use disorder. The study is currently suspended.
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CLINICAL_TRIALS research · 2026-04-07Clinical Trial Update: rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder [NA]
A clinical trial sponsored by the New York State Psychiatric Institute is evaluating repetitive transcranial magnetic stimulation with cogni…
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CLINICAL_TRIALS trial_result · 2026-04-01Clinical Trial Update: Pioglitazone as an Adjunct to Cognitive-Behavioral Therapy for Cocaine Relapse Prevention [Phase 2]
A Phase 2 clinical trial evaluated pioglitazone as an adjunct to cognitive-behavioral therapy for relapse prevention in Cocaine Use Disorder…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: LDART for Stimulant Use Disorder [NA]
The document reports a Yale University-sponsored clinical trial evaluating LDART for stimulant use disorders, including cocaine use disorder…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: AAV8-hCocH for Cocaine Use Disorder [Phase 1]
Phase 1 trial update for AAV8-hCocH in cocaine use disorder shows the study is active but not recruiting.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Repurposing Semaglutide for the Treatment of Cocaine Use Disorder [Phase 2]
Phase 2 study evaluating repurposed semaglutide for cocaine use disorder is currently recruiting. The University of Texas Health Science Cen…
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder [Phase 2]
A Phase 2 clinical trial evaluating the efficacy and safety of sustained-release dextroamphetamine for cocaine use disorder. The study statu…
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Contingency Management for Drug Use: Does Age Matter? [NA]
Clinical trial update on contingency management for drug use examining whether age affects outcomes; the study is currently active but not r…
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CLINICAL_TRIALS withdrawal · 2026-03-13Clinical Trial Update: Exenatide For Reducing the Reinforcing Effects of Cocaine [Phase 1]
Phase 1 clinical trial evaluating exenatide for reducing reinforcing effects in Cocaine Use Disorder was withdrawn.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories [NA]
A clinical trial investigating reconsolidation blockade of intrusive trauma- and cocaine-related memories has completed.
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: Transcranial Direct Current Stimulation (tDCS) for Treatment of Cocaine Use Disorder [NA]
A clinical trial update indicates that a study evaluating transcranial direct current stimulation as a treatment for cocaine use disorder is…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Efficacy of Clonidine in Reducing Craving in Inpatients With Cocaine and Crack Use Disorder [Phase 4]
Phase 4 clinical trial evaluating clonidine to reduce cravings in inpatients with cocaine use disorder (including crack cocaine use) that is…
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CLINICAL_TRIALS research · 2026-02-18Clinical Trial Update: Web-based Alcohol- or Cocaine-specific Inhibition Training in Adolescents and Young Adults With Substance Use Disorder [NA]
A web-based inhibition training study for adolescents and young adults with alcohol use disorder and cocaine use disorder is currently recru…
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CLINICAL_TRIALS research · 2026-02-12Clinical Trial Update: Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives [NA]
Wake Forest University Health Sciences is recruiting participants for a study on dynamic incentives to encourage abstinence in opioid-use an…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Cariprazine for Comorbid Cocaine and Opioid Use Disorder [Phase 2]
A Phase 2 study evaluating cariprazine for individuals with comorbid cocaine use disorder and opioid use disorder has completed.
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: CRACK-TARGET 1: Descriptive Study of Observed Behavioral Sensitization and Expectations [NA]
This is a descriptive clinical trial (CRACK-TARGET 1) examining observed behavioral sensitization and expectations in individuals with cocai…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder [NA]
A clinical trial is testing approach bias modification training as part of treatment for cocaine use disorder, with recruitment currently on…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Treating Polysubstance Use Using a Novel Digital Technology [Phase 3]
This entry reports that a Phase 3 trial evaluating a novel digital technology to treat polysubstance use, including opioid use disorder and …
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Behavioral Effects of Drugs (Inpatient): 43 (Opioids, Cocaine, n-Acetylcysteine) [EARLY_Phase 1]
An EARLY_PHASE1 inpatient trial evaluating behavioral effects of opioids, cocaine, and N-acetylcysteine in individuals with cocaine use diso…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Temporal Window and Episodic Future Thinking in CUD [NA]
Update on a completed clinical trial evaluating temporal window and episodic future thinking strategies for Cocaine Use Disorder.
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Cocaine and Pentoxifylline (BED IN 47) [EARLY_Phase 1]
An early phase 1 clinical study investigating pentoxifylline for cocaine use disorder, with recruiting status.