Clinically Isolated Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS) [Phase 2]
This Phase 2 clinical trial tests natalizumab for inflammatory demyelination suggestive of multiple sclerosis or definite multiple sclerosis…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Clinical Monitoring, MRI and Neuro-Ophthalmology of a Cohort of Patients With a Clinically Isolated Syndrome (CIS)
This completed clinical trial update describes monitoring, MRI and neuro-ophthalmology assessments in a cohort of patients with Clinically I…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy [Phase 4]
Phase 4 trial update evaluating B cell levels in infants potentially exposed to ocrelizumab during pregnancy, with results posted.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab [Phase 4]
Phase 4 study evaluating B cell levels in infants of lactating women with clinically isolated syndrome or multiple sclerosis who are receivi…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies
A completed study evaluating changes in immunoglobulin levels in patients with relapsing multiple sclerosis treated with anti-CD20 therapies…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Prebiotic vs Probiotic in Multiple Sclerosis [NA]
A completed clinical trial comparing prebiotic versus probiotic interventions in individuals with Multiple Sclerosis and Clinically Isolated…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
This clinical trial update reports the completion of a study evaluating the effectiveness and safety of Mayzent (fingolimod) in Chinese pati…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Minocycline in MS: Confirmation of Benefit [Phase 3]
Phase 3 trial investigating minocycline for multiple sclerosis and clinically isolated syndrome; the study is terminated after completion.
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: Mitochondrial Dysfunction and Disease Progression
A completed clinical trial (NCT02549703) examining the role of mitochondrial dysfunction in disease progression across multiple sclerosis fo…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™ [Phase 4]
A Phase 4 trial evaluated Rebif (interferon beta-1a) delivered via the RebiSmart device for effectiveness in Clinically Isolated Syndrome an…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Dose-related Effects of Vitamin D3 on Immune Responses in Patients With Clinically Isolated Syndrome [Phase 1, Phase 2]
A completed Phase 1/2 trial assessed dose-related effects of Vitamin D3 on immune responses in patients with Clinically Isolated Syndrome an…
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CLINICAL_TRIALS trial_result · 2017-04-04Clinical Trial Update: AT RISK FOR MS - Clinical Conversion of Female Monozygotic Twins Discordant for CIS/MS
A completed clinical trial investigating the conversion to multiple sclerosis in female monozygotic twins discordant for clinically isolated…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Minocycline in Clinically Isolated Syndromes (CIS) [Phase 3]
Phase 3 trial of minocycline in Clinically Isolated Syndrome and early relapse of multiple sclerosis has completed; results are not detailed…
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CLINICAL_TRIALS trial_result · 2016-11-09Clinical Trial Update: A Pilot Study to Assess microRNA Biomarkers in Early and Later Stage Multiple Sclerosis
This update reports the results of a pilot study evaluating microRNA biomarkers in early and later stages of multiple sclerosis.
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CLINICAL_TRIALS trial_result · 2016-10-06Clinical Trial Update: Nanocort in Acute Exacerbation of Relapsing-Remitting Multiple Sclerosis (MS) [Phase 2]
A Phase 2 trial of Nanocort for acute exacerbations of relapsing-remitting multiple sclerosis and clinically isolated syndrome has been term…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Longitudinal Study in Clinically Isolated Syndrome (CIS) Patients Treated With Interferon Beta
The longitudinal study of interferon beta in patients with clinically isolated syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2016-05-06Clinical Trial Update: Trichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated Syndrome [Phase 2]
A Phase 2 trial evaluating Trichuris suis ova (TSO) for relapsing-remitting multiple sclerosis and clinically isolated syndrome has been ter…
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CLINICAL_TRIALS trial_result · 2016-03-15Clinical Trial Update: Open Label Extension of Prior TERMS Study to Treat Relapsing Forms of Multiple Sclerosis [Phase 2]
Open-label extension of Opexa Therapeutics' TERMS Phase 2 trial for relapsing forms of multiple sclerosis was terminated, with results poste…
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CLINICAL_TRIALS trial_result · 2014-08-21Clinical Trial Update: Betaferon® Regulatory Post-Marketing Surveillance
A completed regulatory post-marketing surveillance trial for Betaferon (interferon beta-1b) assessing safety in multiple sclerosis and clini…
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CLINICAL_TRIALS trial_result · 2013-10-28Clinical Trial Update: Long-term Follow-Up of Patients Who Participated in Study 27025 (REFLEX) [Phase 3]
This document provides long-term follow-up results from participants in the REFLEX Phase 3 trial investigating treatment for multiple sclero…
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CLINICAL_TRIALS trial_result · 2012-04-04Clinical Trial Update: A Prospective Study Looking at the Use of Rebif® in Subjects With Clinically Isolated Syndrome [Phase 3]
A Phase 3 trial evaluating Rebif (interferon beta-1a) in subjects with clinically isolated syndrome has completed. Results were posted in 20…
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CLINICAL_TRIALS trial_result · 2011-11-03Clinical Trial Update: Atorvastatin (Lipitor) Therapy in Patients With Clinically Isolated Syndrome (CIS) at Risk for Multiple Sclerosis [Phase 2]
A Phase 2 trial evaluating atorvastatin (Lipitor) in patients with clinically isolated syndrome at risk for multiple sclerosis has completed…
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CLINICAL_TRIALS trial_result · 2011-07-22Clinical Trial Update: Safety/Effectiveness of Adding Monthly Dexamethasone to Weekly Avonex for MS
A completed trial evaluating the safety and effectiveness of adding monthly dexamethasone to weekly Avonex in people with relapsing-remittin…
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CLINICAL_TRIALS trial_result · 2011-06-10Clinical Trial Update: Cohort Study of Clinically Isolated Syndrome and Early Multiple Sclerosis
A clinical trial update for a cohort study evaluating progression from clinically isolated syndrome to early multiple sclerosis. The current…
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CLINICAL_TRIALS trial_result · 2010-02-10Clinical Trial Update: Optical Coherence Tomography: Glatiramer in Clinically Isolated Syndrome or Early Relapsing Remitting Multiple Sclerosis (MS) [Phase 4]
Phase 4 clinical trial evaluating glatiramer acetate in clinically isolated syndrome or early relapsing-remitting multiple sclerosis; uses o…