Clinically Isolated Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Assessing Changes in Multi-parametric MRI in Patients With Acute Demyelinating Lesions Taking Clemastine Fumarate as a Myelin Repair Therapy [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/2 study evaluating clemastine fumarate as a myelin repair therapy in patients with acute demy…
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Autoimmune Intervention Mastery Course Study [NA]
Clinical trial update indicates the Autoimmune Intervention Mastery Course Study is currently recruiting participants for several conditions…
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CLINICAL_TRIALS research · 2026-02-03Clinical Trial Update: Pathogenicity of B and CD4 T Cell Subsets in Multiple Sclerosis [NA]
A clinical trial is investigating the pathogenicity of B and CD4 T cell subsets in multiple sclerosis and is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-26Clinical Trial Update: Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset [Phase 4]
The update summarizes a Phase 4 study evaluating the effects of ocrelizumab on cerebrospinal fluid biomarkers at the onset of multiple scler…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Natalizumab for the Treatment of People With Inflammatory Demyelination Suggestive of Multiple Sclerosis, or Definite Multiple Sclerosis, at First Presentation (AttackMS) [Phase 2]
This Phase 2 clinical trial tests natalizumab for inflammatory demyelination suggestive of multiple sclerosis or definite multiple sclerosis…
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Clinnova-MS: A Prospective Cohort Study of Patients With Multiple Sclerosis: A Trans-regional Digital Health Effort Unlocking the Potential of Artificial Intelligence and Data Science in Health Care
A prospective cohort study called Clinnova-MS investigates AI and data science applications in health care for various forms of multiple scl…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis [NA]
A clinical trial update for NCT04009005 studying clinically isolated syndrome and relapsing-remitting multiple sclerosis; the study is curre…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.
This clinical trial is a multicenter retrospective observational study evaluating the clinical impact of AI-assisted MRI care in multiple sc…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center Study [NA]
This is an update on an ongoing prospective multi-center study evaluating AI-assisted care for people with multiple sclerosis and related co…
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CLINICAL_TRIALS trial_result · 2025-12-03Clinical Trial Update: Clinical Monitoring, MRI and Neuro-Ophthalmology of a Cohort of Patients With a Clinically Isolated Syndrome (CIS)
This completed clinical trial update describes monitoring, MRI and neuro-ophthalmology assessments in a cohort of patients with Clinically I…
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CLINICAL_TRIALS research · 2025-10-07Clinical Trial Update: Glymphatic MRI in Clinically Isolated Syndrome
University of Exeter is conducting a clinical trial to evaluate glymphatic MRI in Clinically Isolated Syndrome, currently recruiting. The st…
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Kappa Free Light Chains (KFLC) in Multiple Sclerosis (MS) and Clinically Isolated Syndrome (CIS)
This clinical trial update notes that a study evaluating kappa free light chains as biomarkers in multiple sclerosis and clinically isolated…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Predictive Value of the Optic Nerve Involvement in Clinically Isolated Syndrome [NA]
An ongoing clinical study investigates whether optic nerve involvement can predict progression in Clinically Isolated Syndrome and multiple …
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: A Study Evaluating B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy [Phase 4]
Phase 4 trial update evaluating B cell levels in infants potentially exposed to ocrelizumab during pregnancy, with results posted.
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis
An ongoing IOBA-sponsored study is evaluating visual processing speed and objective ocular movement analysis in individuals with Multiple Sc…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)
Clinical trial registry update for the PRISMA pregnancy registry, collecting data on infants and maternal serum/milk analysis to assess expo…
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: A Study Evaluating B Cell Levels In Infants Of Lactating Women With CIS Or MS Receiving Ocrelizumab [Phase 4]
Phase 4 study evaluating B cell levels in infants of lactating women with clinically isolated syndrome or multiple sclerosis who are receivi…
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CLINICAL_TRIALS research · 2024-08-07Clinical Trial Update: Sun Yat-Sen Cohort of CNS Idiopathic Inflammatory Demyelinating Diseases
Sun Yat-Sen Memorial Hospital is conducting a cohort study of CNS idiopathic inflammatory demyelinating diseases and is currently recruiting…
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CLINICAL_TRIALS trial_result · 2024-07-29Clinical Trial Update: Study to Assess Changes in Immunoglobulins in Patients With Relapsing Multiple Sclerosis Treated With Anti-CD20 Therapies
A completed study evaluating changes in immunoglobulin levels in patients with relapsing multiple sclerosis treated with anti-CD20 therapies…
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CLINICAL_TRIALS research · 2024-07-05Clinical Trial Update: Pregnancy Cohort in Multiple Sclerosis (MS)
A pregnancy cohort is being evaluated within a multiple sclerosis trial conducted by Charite University in Berlin, and the study is currentl…
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CLINICAL_TRIALS trial_result · 2024-05-22Clinical Trial Update: Prebiotic vs Probiotic in Multiple Sclerosis [NA]
A completed clinical trial comparing prebiotic versus probiotic interventions in individuals with Multiple Sclerosis and Clinically Isolated…
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
This clinical trial update reports the completion of a study evaluating the effectiveness and safety of Mayzent (fingolimod) in Chinese pati…
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CLINICAL_TRIALS trial_result · 2023-03-24Clinical Trial Update: Minocycline in MS: Confirmation of Benefit [Phase 3]
Phase 3 trial investigating minocycline for multiple sclerosis and clinically isolated syndrome; the study is terminated after completion.
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CLINICAL_TRIALS trial_result · 2019-02-20Clinical Trial Update: Mitochondrial Dysfunction and Disease Progression
A completed clinical trial (NCT02549703) examining the role of mitochondrial dysfunction in disease progression across multiple sclerosis fo…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Effectiveness of Rebif® in Clinically Isolated Syndrome and Relapsing Multiple Sclerosis Using RebiSmart™ [Phase 4]
A Phase 4 trial evaluated Rebif (interferon beta-1a) delivered via the RebiSmart device for effectiveness in Clinically Isolated Syndrome an…