Clear Cell Renal Cell Carcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors [Phase 2]
Ipsen-sponsored Phase 2 trial evaluating cabozantinib as second-line treatment for locally advanced or metastatic renal cell carcinoma with …
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CLINICAL_TRIALS research · 2024-12-18Clinical Trial Update: A Study of Cadonilimab（AK104） Plus Lenvatinib in Previous Immunotherapy Treated Advanced/Metastatic Clear Cell Renal Cell Carcinoma [Phase 2]
Phase 2 trial evaluating Cadonilimab (AK104) in combination with Lenvatinib for previously immunotherapy-treated, advanced or metastatic cle…
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EMA approval · 2024-12-13First medicine to treat rare genetic disorder causing cysts and tumours
The European Medicines Agency approved belzutifan (brand name Welireg) as the first medicine to treat von Hippel-Lindau disease and advanced…
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CLINICAL_TRIALS trial_result · 2024-12-03Clinical Trial Update: HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma [Phase 1]
Phase 1 trial update for HERV-E TCR-transduced autologous T cells in metastatic clear cell renal cell carcinoma, with results posted.
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: A Study of Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018) [Phase 1]
This is a Phase 1 study update of belzutifan (MK-6482) in participants with advanced clear cell renal cell carcinoma. The trial is currently…
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CLINICAL_TRIALS trial_result · 2024-11-21Clinical Trial Update: A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy [Phase 2]
This Phase II trial evaluated Axitinib in patients with clear-cell metastatic renal cell carcinoma unsuitable for nephrectomy and has comple…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney Cancer [Phase 1, Phase 2]
Phase 1/2 trial results for the combination of sitravatinib and nivolumab in patients with advanced or metastatic renal cell carcinoma (incl…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012) [Phase 3]
Phase 3 trial MK-6482-012 evaluating pembrolizumab with belzutifan and lenvatinib, or pembrolizumab with quavonlimab and lenvatinib, in adva…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: Combination of Toripalimab and JS004 Therapy for ccRCC [Phase 2]
Phase 2 clinical trial evaluating the combination of toripalimab and JS004 therapy for clear cell renal cell carcinoma is currently recruiti…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: A Phase 1/2a Study of 23ME-00610 in Patients With Advanced Solid Malignancies [Phase 1, Phase 2]
Clinical trial registry entry for a Phase 1/2a study of 23ME-00610 in patients with advanced solid malignancies, including several gynecolog…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: 68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma [NA]
Clinical trial update describing a PET/CT imaging study using 68Ga-C1 for Carbonic Anhydrase IX in patients with clear cell renal cell carci…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours [Phase 1]
This clinical trial update reports the completion of a first-in-human Phase 1 study evaluating AZD8701 with or without durvalumab in adults …
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics and Effectiveness of AGS-16C3F Monotherapy in Subjects With Renal Cell Carcinoma (RCC) of Clear Cell or Papillary Histology [Phase 1]
Phase 1 study assessing safety, pharmacokinetics, and preliminary effectiveness of AGS-16C3F as monotherapy in renal cell carcinoma with cle…
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CLINICAL_TRIALS research · 2024-10-26Clinical Trial Update: Evaluation of Urinary Exosomes Presence From Clear Cell Renal Cell Carcinoma
A clinical trial is currently recruiting to evaluate the presence of urinary exosomes in patients with clear cell renal cell carcinoma.
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CLINICAL_TRIALS trial_result · 2024-10-15Clinical Trial Update: Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial of JK08 for unresectable locally advanced or metastatic cancer conducted by Salubris Biotherapeutics is cur…
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CLINICAL_TRIALS research · 2024-09-27Clinical Trial Update: 68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC. [Phase 2]
Phase 2 trial update for 68Ga-NY104 PET/CT guided radiation therapy in clear cell renal cell carcinoma; the study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: MK-3795 (PT2385) for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma (MK-3795-003) [Phase 2]
Phase 2 trial of MK-3795 (PT2385) for Von Hippel-Lindau–associated clear cell renal cell carcinoma has completed with results posted in 2024…
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CLINICAL_TRIALS other · 2024-08-28Clinical Trial Update: Cardenilimab Combined With Lenvatinib in Patients With Perioperative Resectable Clear Cell Renal Cell Carcinoma. [Phase 2]
A Phase 2 clinical trial evaluating Cardenilimab plus lenvatinib for perioperative, resectable clear cell renal cell carcinoma; the study st…
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CLINICAL_TRIALS trial_result · 2024-08-20Clinical Trial Update: A CT-BASED Deep Learning Model for Predicting WHO/ISUP Pathological Grades of Clear Cell Renal Cell Carcinoma (ccRCC) :A Multicenter Cohort Study
A multicenter cohort study evaluates a CT-based deep learning model to predict WHO/ISUP pathological grades in clear cell renal cell carcino…
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CLINICAL_TRIALS trial_result · 2024-08-14Clinical Trial Update: Trial of X4P-001 in Participants With Advanced Renal Cell Carcinoma [Phase 1, Phase 2]
Results from a Phase 1/2 trial of X4P-001 in participants with advanced renal cell carcinoma have been posted. The study includes the clear …
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CLINICAL_TRIALS research · 2024-08-14Clinical Trial Update: A Study of HS-10516 in Patients With VHL Syndrome Associated Tumors [Phase 1]
Phase 1 trial update for HS-10516 in Von Hippel-Lindau-associated tumors, currently recruiting for VHL-deficient clear cell renal cell carci…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer [Phase 2]
Phase 2 neoadjuvant trial of cabozantinib for locally advanced renal cell carcinoma has posted results. The study includes patients with cle…
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CLINICAL_TRIALS trial_result · 2024-08-05Clinical Trial Update: A Study to go Back Into Records and Observe How People With Metastatic Renal Cell Carcinoma (mRCC) Who Received a Medicine Called Sunitinib Responded to This Medicine.
This clinical trial update summarizes outcomes observed in patients with metastatic renal cell carcinoma treated with sunitinib, based on re…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer [Phase 1]
This Phase 1 trial evaluates CBM588 in combination with nivolumab and ipilimumab for advanced or stage IV renal cell carcinoma; the study ha…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases [Phase 2]
Phase 2 clinical trial update evaluating the combination of radiosurgery and nivolumab for brain metastases in various cancers, with complet…