Clear Cell Renal Cell Carcinoma

CLINICAL_TRIALS trial_result · 2025-05-21

Clinical Trial Update: Pharmacokinetics, Biodistribution, Radiation Dose and Safety Study of 68Ga-NYM005 in Patients [Phase 1, Phase 2]

This report summarizes pharmacokinetics, biodistribution, radiation dose, and safety findings from a Phase 1/2 study of the radiopharmaceuti…

CLINICAL_TRIALS trial_result · 2025-05-20

Clinical Trial Update: SLM + Axitinib for Clear Cell RCC [Phase 1]

Clinical trial update reports completion of a Phase 1 study evaluating SLM in combination with axitinib for advanced/metastatic clear cell r…

CLINICAL_TRIALS trial_result · 2025-01-30

Clinical Trial Update: Daratumumab in Treating Patients with Muscle Invasive Bladder Cancer or Metastatic Kidney Cancer [EARLY_Phase 1]

This early-phase 1 trial update reports completion of a study evaluating daratumumab in patients with muscle-invasive bladder cancer and met…

CLINICAL_TRIALS trial_result · 2025-01-24

Clinical Trial Update: Visceral Fat Area as a Prognostic Biomarker in Clear Cell Renal Cell Carcinoma: A Multicenter Study on Postoperative Survival

A completed multicenter study evaluates visceral fat area as a prognostic biomarker for postoperative survival in patients with clear cell r…

CLINICAL_TRIALS trial_result · 2025-01-16

Clinical Trial Update: Evaluation of HPGD and SCLO2A1 Expression in Clear Cell Renal Cell Carcinoma Patients

The trial evaluated expression of HPGD and SCLO2A1 in patients with Clear Cell Renal Cell Carcinoma and is marked as completed.

CLINICAL_TRIALS trial_result · 2025-01-15

Clinical Trial Update: Prognostic Significance of the Lung Immune Prognostic Index (LIPI) in Postoperative Clear Cell Renal Cell Carcinoma: a Multicenter Retrospective Cohort Study

A multicenter retrospective study assesses whether the Lung Immune Prognostic Index (LIPI) has prognostic value after surgical resection in …

CLINICAL_TRIALS trial_result · 2024-12-27

Clinical Trial Update: 89Zr-TLX250 for PET/CT Imaging of ccRCC - ZIRCON-CP Study [Phase 3]

Phase 3 imaging study ZIRCON-CP evaluating 89Zr-TLX250 for PET/CT in clear cell renal cell carcinoma is currently recruiting.

CLINICAL_TRIALS trial_result · 2024-12-19

Clinical Trial Update: Study of Cabozantinib as 2nd Line Treatment in Subjects With Locally Advanced or Metastatic Renal Cell Carcinoma (RCC) With a Clear-Cell Component Who Progressed After 1st Line Treatment With Checkpoint Inhibitors [Phase 2]

Ipsen-sponsored Phase 2 trial evaluating cabozantinib as second-line treatment for locally advanced or metastatic renal cell carcinoma with …

CLINICAL_TRIALS trial_result · 2024-12-03

Clinical Trial Update: HERV-E TCR Transduced Autologous T Cells in People With Metastatic Clear Cell Renal Cell Carcinoma [Phase 1]

Phase 1 trial update for HERV-E TCR-transduced autologous T cells in metastatic clear cell renal cell carcinoma, with results posted.

CLINICAL_TRIALS trial_result · 2024-11-21

Clinical Trial Update: A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy [Phase 2]

This Phase II trial evaluated Axitinib in patients with clear-cell metastatic renal cell carcinoma unsuitable for nephrectomy and has comple…

CLINICAL_TRIALS trial_result · 2024-11-19

Clinical Trial Update: Sitravatinib and Nivolumab in Treating Patients With Advanced or Metastatic Kidney Cancer [Phase 1, Phase 2]

Phase 1/2 trial results for the combination of sitravatinib and nivolumab in patients with advanced or metastatic renal cell carcinoma (incl…

CLINICAL_TRIALS trial_result · 2024-11-05

Clinical Trial Update: First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours [Phase 1]

This clinical trial update reports the completion of a first-in-human Phase 1 study evaluating AZD8701 with or without durvalumab in adults …

CLINICAL_TRIALS trial_result · 2024-11-01

Clinical Trial Update: A Study to Assess the Safety, Pharmacokinetics and Effectiveness of AGS-16C3F Monotherapy in Subjects With Renal Cell Carcinoma (RCC) of Clear Cell or Papillary Histology [Phase 1]

Phase 1 study assessing safety, pharmacokinetics, and preliminary effectiveness of AGS-16C3F as monotherapy in renal cell carcinoma with cle…

CLINICAL_TRIALS trial_result · 2024-10-15

Clinical Trial Update: Study of JK08 in Patients with Unresectable Locally Advanced or Metastatic Cancer [Phase 1, Phase 2]

A Phase 1/Phase 2 clinical trial of JK08 for unresectable locally advanced or metastatic cancer conducted by Salubris Biotherapeutics is cur…

CLINICAL_TRIALS trial_result · 2024-09-24

Clinical Trial Update: MK-3795 (PT2385) for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma (MK-3795-003) [Phase 2]

Phase 2 trial of MK-3795 (PT2385) for Von Hippel-Lindau–associated clear cell renal cell carcinoma has completed with results posted in 2024…

CLINICAL_TRIALS trial_result · 2024-08-20

Clinical Trial Update: A CT-BASED Deep Learning Model for Predicting WHO/ISUP Pathological Grades of Clear Cell Renal Cell Carcinoma (ccRCC) :A Multicenter Cohort Study

A multicenter cohort study evaluates a CT-based deep learning model to predict WHO/ISUP pathological grades in clear cell renal cell carcino…

CLINICAL_TRIALS trial_result · 2024-08-14

Clinical Trial Update: Trial of X4P-001 in Participants With Advanced Renal Cell Carcinoma [Phase 1, Phase 2]

Results from a Phase 1/2 trial of X4P-001 in participants with advanced renal cell carcinoma have been posted. The study includes the clear …

CLINICAL_TRIALS trial_result · 2024-08-13

Clinical Trial Update: Neoadjuvant Cabozantinib in Treating Patients With Locally Advanced Kidney Cancer [Phase 2]

Phase 2 neoadjuvant trial of cabozantinib for locally advanced renal cell carcinoma has posted results. The study includes patients with cle…

CLINICAL_TRIALS trial_result · 2024-08-05

Clinical Trial Update: A Study to go Back Into Records and Observe How People With Metastatic Renal Cell Carcinoma (mRCC) Who Received a Medicine Called Sunitinib Responded to This Medicine.

This clinical trial update summarizes outcomes observed in patients with metastatic renal cell carcinoma treated with sunitinib, based on re…

CLINICAL_TRIALS trial_result · 2024-07-03

Clinical Trial Update: CBM588, Nivolumab, and Ipilimumab in Treating Patients With Stage IV or Advanced Kidney Cancer [Phase 1]

This Phase 1 trial evaluates CBM588 in combination with nivolumab and ipilimumab for advanced or stage IV renal cell carcinoma; the study ha…

CLINICAL_TRIALS trial_result · 2024-06-28

Clinical Trial Update: Combining Radiosurgery and Nivolumab in the Treatment of Brain Metastases [Phase 2]

Phase 2 clinical trial update evaluating the combination of radiosurgery and nivolumab for brain metastases in various cancers, with complet…

CLINICAL_TRIALS trial_result · 2024-06-17

Clinical Trial Update: A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma (MK-3795-001) [Phase 1]

This document describes a Phase 1 dose-escalation trial of PT2385 in patients with advanced clear cell renal cell carcinoma (renal cell carc…

CLINICAL_TRIALS trial_result · 2024-06-05

Clinical Trial Update: Study of Sitravatinib, Nivolumab and Ipilimumab in Advanced or Metastatic Clear-Cell Renal Cell Carcinoma or Other Solid Malignancies [Phase 1]

Phase 1 study evaluating a triple combination of sitravatinib, nivolumab, and ipilimumab in advanced or metastatic clear-cell renal cell car…

CLINICAL_TRIALS trial_result · 2024-05-17

Clinical Trial Update: 89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study [Phase 3]

Phase 3 ZIRCON trial evaluating the PET/CT imaging agent 89Zr-TLX250 for clear cell renal cell carcinoma has completed with results posted.

CLINICAL_TRIALS trial_result · 2023-07-24

Clinical Trial Update: 68Ga-NY104 PET/CT in Patients With Metastatic Clear Cell Renal Cell Carcinoma [Phase 2]

Phase 2 trial update for 68Ga-NY104 PET/CT imaging in metastatic clear cell renal cell carcinoma.

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