Cirrhosis
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2024-07-10Clinical Trial Update: Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant.
This clinical study aims to evaluate cirrhotic cardiomyopathy in patients awaiting liver transplant using cardiac MRI to assess cardiac func…
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CLINICAL_TRIALS research · 2024-06-25Clinical Trial Update: The Safety and Efficacy of Alverine in the Treatment of Cirrhotic Portal Hypertension [Phase 2, Phase 3]
Clinical trial update indicates evaluation of alverine for cirrhotic portal hypertension in Phase 2 and Phase 3, with the study currently no…
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CLINICAL_TRIALS research · 2024-06-14Clinical Trial Update: Multi-analyte Blood Test Clinical Trial
This clinical trial update notes that a multi-analyte blood test is currently recruiting for evaluation in patients with cirrhosis and hepat…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Liver Cancer Disparities in American Indian and Alaska Native Persons [Phase 2]
This clinical trial update discusses a Phase 2 study investigating liver cancer disparities affecting American Indian and Alaska Native peop…
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CLINICAL_TRIALS research · 2024-06-04Clinical Trial Update: Evaluation of Cardiac Function in Acutely Decompensated Cirrhosis
A clinical trial update describing evaluation of cardiac function in patients with acutely decompensated cirrhosis; the study is currently a…
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CLINICAL_TRIALS research · 2024-05-20Clinical Trial Update: The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China
A two-center retrospective cohort study from China examining how cirrhosis affects liver transplantation outcomes for hepatocellular carcino…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: VE303 for Treatment of Hepatic Encephalopathy (HE) [Phase 2]
Phase 2 clinical trial results for VE303 in hepatic encephalopathy have been posted after completion of the study. The trial enrolled patien…
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CLINICAL_TRIALS withdrawal · 2024-05-07Clinical Trial Update: Efficacy and Safety of Midodrine in Refractory or Recurrent Ascites in Children With Cirrhosis. [NA]
A clinical trial evaluating midodrine for refractory or recurrent ascites in children with cirrhosis has been withdrawn.
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CLINICAL_TRIALS research · 2024-05-07Clinical Trial Update: Clinical Value of the Developed Scoring Systems for Predicting Spontaneous Bacterial Peritonitis in Cirrhotic Ascites
A ClinicalTrials.gov entry describing a prospective study to evaluate scoring systems for predicting spontaneous bacterial peritonitis in pa…
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FDA approval · 2024-04-30FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Accord Healthcare Inc.)
The FDA approved a supplemental application for hydrochlorothiazide filed by Accord Healthcare Inc. under ANDA 202556. The document does not…
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CLINICAL_TRIALS trial_result · 2024-03-19Clinical Trial Update: Efficacy and Durability of Hepatitis A Vaccination in Patients With Advanced Fibrosis and Cirrhosis [Phase 4]
Phase 4 trial update evaluating efficacy and durability of hepatitis A vaccination in patients with advanced fibrosis and cirrhosis.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy. [NA]
A completed clinical trial (BRAINFOOD) investigating prevention of recurrent hepatic encephalopathy in patients with cirrhosis and ascites; …
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis [Phase 4]
A Phase 4 clinical trial evaluated the effect of branched-chain amino acids (BCAA) on muscle cramps in patients with cirrhosis, completed by…
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CLINICAL_TRIALS trial_result · 2023-12-15Clinical Trial Update: A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury [Phase 2]
Phase 2 trial assessing OCE-205 in participants with cirrhosis and ascites who developed hepatorenal syndrome-acute kidney injury has comple…
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CLINICAL_TRIALS trial_result · 2023-11-30Clinical Trial Update: A Study to Evaluate Liver Stiffness With Shear Wave Elastography [NA]
A completed clinical trial evaluating liver stiffness using shear wave elastography in chronic liver disease and advanced fibrosis; results …
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: A Trial to Improve Quality of Life in People With Cirrhosis [Phase 2, Phase 3]
A phase 2/3 trial conducted to improve quality of life in people with cirrhosis has completed and results were posted in 2023.
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CLINICAL_TRIALS withdrawal · 2023-11-18Clinical Trial Update: Transfer Factor Efficacy in the Management of Cirrhosis-associated Immune Dysfunction [Phase 2, Phase 3]
The clinical trial evaluating transfer factor for cirrhosis-associated immune dysfunction was withdrawn.
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Rifamycin in Minimal Hepatic Encephalopathy [Phase 2]
Phase 2 trial update for rifamycin in minimal hepatic encephalopathy has completed.
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FDA approval · 2023-07-21FDA Approved: TORSEMIDE — Supplemental Application (Hikma Pharmaceuticals USA Inc.)
The FDA approved Hikma Pharmaceuticals USA Inc.'s supplemental application for torsemide, granting approval of a generic torsemide product u…
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CLINICAL_TRIALS withdrawal · 2023-07-20Clinical Trial Update: Nalmefene in Patients With Alcoholic Compensated Cirrhosis for the Treatment of Alcohol Dependence. [Phase 3]
A Phase 3 trial evaluating nalmefene for alcohol dependence in patients with compensated alcoholic cirrhosis has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. [Phase 4]
A Phase 4 clinical trial evaluating beta-blockers vs placebo for primary prevention of esophageal varices in patients with cirrhosis and por…
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CLINICAL_TRIALS trial_result · 2023-05-16Clinical Trial Update: Mesenchymal Stem Cell Transplantation in Decompensated Cirrhosis [Phase 2]
Phase 2 clinical trial evaluating mesenchymal stem cell transplantation in decompensated cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2023-05-09Clinical Trial Update: Allopurinol to Prevent Cirrhosis Related Morbidities [Phase 2, Phase 3]
A Phase 2/Phase 3 trial evaluating allopurinol for prevention of cirrhosis-related morbidities has completed.
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CLINICAL_TRIALS trial_result · 2023-04-20Clinical Trial Update: Sofosbuvir, Daclatasvir, Ribavirin for Hepatitis C Virus (HCV) Cirrhotics [Phase 3]
Phase 3 trial evaluating sofosbuvir, daclatasvir, and ribavirin in hepatitis C patients with cirrhosis has completed.
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CLINICAL_TRIALS trial_result · 2023-02-14Clinical Trial Update: Hepatocellular Carcinoma Surveillance in Cirrhotics [NA]
Clinical trial update on hepatocellular carcinoma surveillance in patients with cirrhosis; study completed with results posted.