Cirrhosis
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Non-invasive Methods for Predicting Decompensation of Chronic Liver Disease
A clinical trial update indicates a study on non-invasive methods to predict decompensation in chronic liver disease is currently enrolling …
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Nutritional Assesment in Patients With Cirrhosis
Clinical trial update indicating that a nutritional assessment study in patients with cirrhosis is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Improving Pain Management and Opioid Safety for Patients With Cirrhosis [NA]
The University of Pittsburgh conducted a trial to improve pain management and opioid safety in patients with cirrhosis, and results have bee…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Defining the Mechanisms Underlying Adrenal Insufficiency in Cirrhosis
A University of Virginia clinical trial investigates the mechanisms of adrenal insufficiency in cirrhosis. The study status is COMPLETED.
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Muscle Mass Via UltraSound in Cirrhosis (MMUSCLE)
MMUSCLE is a recruiting clinical trial evaluating ultrasound assessment of muscle mass in patients with cirrhosis, addressing sarcopenia and…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Navitoclax and Sorafenib Tosylate in Treating Patients With Relapsed or Refractory Solid Tumors [Phase 1]
Phase 1 trial evaluating the safety of combining navitoclax with sorafenib tosylate in patients with relapsed or refractory solid tumors, in…
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CLINICAL_TRIALS research · 2024-11-22Clinical Trial Update: Durvalumab (MEDI4736) and Tremelimumab for Hepatocellular Carcinoma in Patients Listed for a Liver Transplant [Phase 2]
A Phase 2 clinical trial evaluating the combination of durvalumab and tremelimumab for hepatocellular carcinoma in patients listed for liver…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: Comparison Between 2-dose Versus 3-dose Regimens of Heplisav B in Cirrhosis [Phase 4]
Phase 4 clinical trial update comparing two-dose versus three-dose regimens of Heplisav-B in patients with cirrhosis, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: TIPS Plus Transvenous Obliteration for Gastric Varices
A completed clinical trial evaluated the combination of transjugular intrahepatic portosystemic shunt (TIPS) with transvenous obliteration f…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: HRS-AKI Treatment With TIPS in Patients With Cirrhosis [NA]
Clinical trial update indicating recruitment for a study evaluating the use of transjugular intrahepatic portosystemic shunt (TIPS) to treat…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Prevention of Recurrent Hepatitis B After Liver Transplantation
This update reports the completion of a clinical trial evaluating strategies to prevent recurrent hepatitis B after liver transplantation, s…
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CLINICAL_TRIALS research · 2024-11-08Clinical Trial Update: Early Ascitis Parencentesis in SBP [NA]
A clinical trial is planned to evaluate early paracentesis in patients with cirrhosis and spontaneous bacterial peritonitis; the trial statu…
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CLINICAL_TRIALS research · 2024-10-15Clinical Trial Update: Pathogenic Metagenomic Next-generation Sequencing to Optimize the Diagnosis of Decompensated Cirrhosis Infection
A clinical trial is evaluating pathogenic metagenomic next-generation sequencing to optimize the diagnosis of infections in patients with de…
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: Integrated Phenotyping of the Gut-plAtelet-Liver AXIS in the Progression of Chronic Liver Disease (iGAL-AXIS)
A clinical trial protocol evaluating integrated phenotyping of the gut-platelet-liver axis to understand progression of chronic liver diseas…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Efficacy of Esmolol in the Identification of Cardiovascular Disorders by Cirrhosis, Diabetes Mellitus and Cardiotoxic Treatments [Phase 3]
A Phase 3 trial is evaluating the efficacy of esmolol in identifying cardiovascular disorders in patients with cirrhosis and diabetes mellit…
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CLINICAL_TRIALS research · 2024-09-20Clinical Trial Update: PET/CT Scans Using the Tracer 11C-Csar, a Bile Acid Analog, to Depict and Visualize Changes in the Hepatobiliary System in Patients With Primary Biliary Cholangitis Before and After Treatment.
An ongoing clinical trial update evaluating the 11C-Csar tracer, a bile acid analog, to image hepatobiliary changes in Primary Biliary Chola…
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FDA approval · 2024-09-19FDA Approved: HYDROCHLOROTHIAZIDE — Supplemental Application (Teva Pharmaceuticals USA, Inc.)
FDA approved a supplemental application for hydrochlorothiazide from Teva Pharmaceuticals USA, Inc. The approval concerns regulatory changes…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: Protocol for Muscle Attenuation Cut-offs in Cirrhosis
A completed clinical trial protocol outlining muscle attenuation cut-offs for assessing myosteatosis and sarcopenia in cirrhosis, including …
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH) [Phase 2]
A Phase 2 trial evaluating the safety and effectiveness of BMS-986263 in adults with compensated cirrhosis due to nonalcoholic steatohepatit…
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CLINICAL_TRIALS trial_result · 2024-08-27Clinical Trial Update: Transjugular Intrahepatic Portosystemic Shunts Improve Survival in Patients With Cirrhosis and Recurrent Ascites
A completed clinical trial suggests that transjugular intrahepatic portosystemic shunts (TIPS) improve survival in patients with cirrhosis a…
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CLINICAL_TRIALS research · 2024-08-02Clinical Trial Update: Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis [Phase 1]
Phase 1 trial evaluating defined green tea catechin extract to prevent liver cancer in people with cirrhosis; the study is currently active …
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CLINICAL_TRIALS trial_result · 2024-08-02Clinical Trial Update: Longitudinal Monitoring of Inflammation in Cirrhosis [NA]
A completed clinical trial evaluating longitudinal monitoring of inflammation in patients with cirrhosis.
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CLINICAL_TRIALS research · 2024-07-23Clinical Trial Update: A Protocol of the Canadian Prospective Study for Hepatocellular Carcinoma Surveillance Using Biomarkers
This document outlines a Canadian prospective protocol to evaluate biomarkers for hepatocellular carcinoma surveillance in patients with cir…
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CLINICAL_TRIALS research · 2024-07-22Clinical Trial Update: Longitudinal Surveillance of Rectal Colonization and Transmission by Resistant Bacteria in Acutely Decompensated Cirrhosis
This ClinicalTrials.gov entry outlines a study to monitor rectal colonization and transmission of resistant bacteria in patients with acutel…
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CLINICAL_TRIALS trial_result · 2024-07-17Clinical Trial Update: Cirrhosis Medical Home [NA]
This clinical trial update notes that the Cirrhosis Medical Home study has completed and results were posted on 2024-07-17. Sponsor is India…