Cirrhosis
📧 Sign up to get email alerts when something new happens for Cirrhosis.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2023-01-18Clinical Trial Update: Synbiotics Interventions for Managing Cirrhosis and Its Complications [Phase 4]
Phase 4 clinical trial assessing synbiotics interventions for cirrhosis and its complications has completed.
-
FDA approval · 2022-12-19FDA Approved: SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE — Supplemental Application (Prasco Laboratories)
FDA approves a supplemental application for the combination product spironolactone and hydrochlorothiazide, manufactured by Prasco Laborator…
-
CLINICAL_TRIALS trial_result · 2022-11-21Clinical Trial Update: Rifaximin Prophylaxis for Spontaneous Bacterial Peritonitis and Hepatorenal Syndrome in Cirrhotic Patients [Phase 2]
Phase 2 trial update on rifaximin prophylaxis for spontaneous bacterial peritonitis and hepatorenal syndrome in cirrhotic patients with asci…
-
CLINICAL_TRIALS trial_result · 2022-10-31Clinical Trial Update: Ropinirole for the Treatment of Muscle Cramps in Patients With Cirrhosis [Phase 4]
Phase 4 trial assessing ropinirole for treating muscle cramps in patients with cirrhosis has completed and results posted.
-
CLINICAL_TRIALS trial_result · 2022-10-12Clinical Trial Update: Safety of Anticoagulant Therapy After Endoscopic Treatment [Phase 4]
Phase 4 trial update assessing the safety of anticoagulant therapy after endoscopic treatment in patients with cirrhosis and portal vein thr…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2022-08-31Clinical Trial Update: Prophylactic Antibiotics in Admitted Cirrhotics [Phase 4]
Phase 4 trial update on prophylactic antibiotics in admitted cirrhotics; completed with posted results.
-
CLINICAL_TRIALS trial_result · 2022-07-21Clinical Trial Update: Efficacy and Safety of SOF/VEL + RBV and SOF/VEL/VOX for 12 Weeks in HCV Subjects With GT3b and Compensated Cirrhosis [Phase 4]
Phase 4 trial updating efficacy and safety of SOF/VEL with or without RBV and SOF/VEL/VOX for 12 weeks in hepatitis C patients with GT3b and…
-
CLINICAL_TRIALS trial_result · 2022-07-01Clinical Trial Update: 20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension [Phase 4]
Phase 4 trial comparing 20% albumin to balanced salt solution for resuscitation in cirrhosis with sepsis-induced hypotension; status current…
-
CLINICAL_TRIALS trial_result · 2022-05-31Clinical Trial Update: HEAL STUDY (Hepatic Encephalopathy and Albumin Study) [Phase 2]
Phase 2 clinical trial update for HEAL STUDY investigating hepatic encephalopathy and albumin in cirrhosis; trial status completed.
-
CLINICAL_TRIALS trial_result · 2022-03-04Clinical Trial Update: Effect of Samsca on Control of Hyponatremia and Extracellular Fluid in Cirrhotic Patients With Ascites [Phase 4]
Phase 4 trial update on Samsca (tolvaptan) regarding control of hyponatremia and extracellular fluid in cirrhosis with ascites; study termin…
-
CLINICAL_TRIALS trial_result · 2022-02-25Clinical Trial Update: Erlotinib Hydrochloride in Preventing Liver Cancer in Patients With Cirrhosis of the Liver [Phase 1, Phase 2]
Clinical trial evaluating Erlotinib hydrochloride for prevention of liver cancer in patients with cirrhosis; study phases completed with res…
-
CLINICAL_TRIALS trial_result · 2022-01-14Clinical Trial Update: Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension [Phase 2]
Phase 2 trial of emricasan, an oral caspase inhibitor, in subjects with NASH cirrhosis and severe portal hypertension has completed with res…
-
CLINICAL_TRIALS trial_result · 2021-12-09Clinical Trial Update: Is Adrenal Insufficiency Under-diagnosed in Hospitalized Cirrhosis Patients? [Phase 3]
A Phase 3 clinical trial investigated whether adrenal insufficiency is under-diagnosed in hospitalized patients with cirrhosis; results have…
-
CLINICAL_TRIALS trial_result · 2021-09-05Clinical Trial Update: Sodium-glucose Linked Transporter 2 (SGLT-2) Inhibitors in Recurrent Ascites: a Pilot RCT [Phase 2]
A Phase 2 pilot randomized trial evaluating SGLT-2 inhibitors for recurrent ascites in cirrhosis, currently with unknown status.
-
CLINICAL_TRIALS trial_result · 2021-08-17Clinical Trial Update: Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903) [Phase 4]
Phase 4 trial update comparing terlipressin to octreotide using functional MRI to assess renal function in cirrhotic patients with acute var…
-
CLINICAL_TRIALS trial_result · 2021-07-28Clinical Trial Update: Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study [Phase 3]
Phase 3 trial update evaluating sildenafil for Fontan-associated liver disease (SiFALD) completed with posted results in 2021.
-
FDA approval · 2021-07-16FDA Approved: TOLVAPTAN — Original Application (Camber Pharmaceuticals, Inc.)
FDA approves Camber Pharmaceuticals' tolvaptan via an original (ANDA) application, indicating a generic tolvaptan product is approved.
-
CLINICAL_TRIALS trial_result · 2021-07-13Clinical Trial Update: Continuous Infusion Terlipressin for Patients With Cirrhosis and Refractory Ascites [Phase 2]
Phase 2 trial update for continuous infusion terlipressin in patients with cirrhosis and refractory ascites has completed with posted result…
-
CLINICAL_TRIALS trial_result · 2021-04-15Clinical Trial Update: Avatrombopaq In Patients With Cirrhosis [Phase 4]
Phase 4 trial update for avatrombopag in patients with cirrhosis and thrombocytopenia, focusing on safety and efficacy in reducing procedura…
-
CLINICAL_TRIALS trial_result · 2021-03-29Clinical Trial Update: Ramelteon for Treatment of Insomnia in Cirrhosis [Phase 4]
Phase 4 clinical trial of ramelteon for insomnia in patients with cirrhosis has completed with results posted.
-
FDA approval · 2021-02-26FDA Approved: SPIRONOLACTONE — Supplemental Application (Mylan Pharmaceuticals Inc.)
The FDA approved a supplemental application for spironolactone from Mylan Pharmaceuticals, resulting in changes to the product labeling as p…
-
CLINICAL_TRIALS trial_result · 2021-01-22Clinical Trial Update: Comparison of Blood Product Use and Bleeding Events During and After Endoscopic or Neurosurgical Procedures in Patients With Cirrhosis and Coagulopathy [NA]
A completed clinical trial comparing blood product use and bleeding events during and after endoscopic or neurosurgical procedures in patien…
-
CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Safety and Tolerability of HepaStem in Patients With Cirrhotic and Pre-cirrhotic NASH Patients [Phase 1, Phase 2]
Clinical trial updates on HepaStem show safety and tolerability in patients with cirrhotic and pre-cirrhotic nonalcoholic steatohepatitis (N…
-
CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Safety, Tolerability and Pharmacodynamics of SYNB1020 [Phase 1, Phase 2]
Phase 1/2 trial update for SYNB1020 focusing on safety, tolerability, and pharmacodynamics in cirrhosis has terminated with posted results.
-
CLINICAL_TRIALS trial_result · 2020-09-04Clinical Trial Update: Companion Protocol for Methacetin Breath Test (MBT) in Conatus Protocol IDN-6556-14
A completed clinical trial update for a companion protocol related to the Methacetin Breath Test in the Conatus protocol; results posted in …