Cirrhosis of the Liver
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CLINICAL_TRIALS trial_result · 2026-07-31Clinical Trial Results: LiveSMART Trial to Prevent Falls in Patients With Cirrhosis [Phase 3]
Phase 3 trial results for LiveSMART evaluating falls prevention in patients with cirrhosis and portal hypertension have been completed with …
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CLINICAL_TRIALS trial_result · 2026-07-02Clinical Trial Results: Liver Fibrosis in Zambian HIV-HBV Co-infected Patients
Clinical trial results in Zambian HIV-HBV co-infected patients evaluated liver fibrosis outcomes; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Effects of Platelet Mimicking Nanoparticles in Patients With Cirrhosis
This is a completed clinical trial evaluating platelet-mimicking nanoparticles in patients with cirrhosis of the liver.
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome
ClinicalTrials.gov update announcing an actively recruiting study of chronic liver diseases associated with alcohol use and metabolic syndro…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Goal-Directed Hemostatic Resuscitation Trial in ACLF Induced Coagulopathy [NA]
The document reports a completed clinical trial evaluating goal-directed hemostatic resuscitation for coagulopathy associated with acute-on-…
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CLINICAL_TRIALS research · 2026-02-24Clinical Trial Update: Liver Cancer Prevention Randomized Control Trial [NA]
This clinical trial update reports an active-not-recruiting randomized controlled trial aimed at preventing liver cancer. The study lists MD…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)
The Liver Cirrhosis Cognitive Decline Scale (LiCCoS) is the subject of a recruiting clinical trial investigating cognitive dysfunction in pa…
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CLINICAL_TRIALS trial_result · 2026-01-20Clinical Trial Update: A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK [Phase 2]
A Phase IIb trial evaluating the safety of Zibotentan in combination with Dapagliflozin in participants with cirrhosis has completed, with r…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Intraabdominal Hypertension and Occurrence of Microaspiration in Cirrhotics Under Mechanical Ventilation
Clinical trial investigating intraabdominal hypertension and microaspiration in cirrhotic patients on mechanical ventilation is currently re…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Echocardiography-guided Cirrhosis and Liver Failure-Intensive Care Protocol Sepsis [NA]
This clinical trial update describes an echocardiography-guided cirrhosis and liver failure ICU protocol for sepsis being tested. The study …
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Periinterventional Coagulation Management of Patients Undergoing a TIPS [NA]
A clinical trial is evaluating periinterventional coagulation management for patients with cirrhosis undergoing a TIPS procedure and is curr…
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CLINICAL_TRIALS trial_result · 2025-11-24Clinical Trial Update: A Study of SIPLIZUMAB in AILD and LT Patients [Phase 1]
Phase 1 clinical trial of SIPLIZUMAB for autoimmune liver disease and liver transplant-related conditions is currently recruiting.
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CLINICAL_TRIALS research · 2025-10-10Clinical Trial Update: Leucine Enriched Essential Amino Acid Mixture to Reverse Muscle Loss in Cirrhosis [NA]
A clinical trial evaluating a leucine-enriched essential amino acid mixture to reverse muscle loss in cirrhosis of the liver. The study is c…
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CLINICAL_TRIALS trial_result · 2025-09-10Clinical Trial Update: LiveSMART Trial to Prevent Falls in Patients With Cirrhosis [Phase 3]
Phase 3 LiveSMART trial evaluating falls prevention in patients with cirrhosis has completed. The study enrolled patients with cirrhosis and…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: A Digital Tongue Diagnosis Model for High- and Low-risk Esophagogastroduodenal Varices in Cirrhosis
This document provides a clinical trial update for a digital tongue diagnosis model intended to assess high- and low-risk esophagogastroduod…
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, PK, and PD Effects of AZD2389 in Participants With Liver Fibrosis and Compensated Cirrhosis. [Phase 2]
A completed Phase 2 clinical trial evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of AZD2389 in participants wi…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Frequency of Portal Hypertension Among Patient With Cirrhotic Liver With Ultrasound
This clinical trial update describes a study assessing the frequency of portal hypertension in patients with liver cirrhosis. The study is c…
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CLINICAL_TRIALS trial_result · 2025-06-25Clinical Trial Update: Trial of Psychoeducational and Hypnosis Interventions on the Fatigue Associated With PBC in Women [NA]
A completed clinical trial from Assistance Publique - Hôpitaux de Paris evaluating psychoeducational and hypnosis interventions to reduce fa…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Evaluation of Long Haul COVID-19 and Vaccine Immunogenicity in Patients With Liver Disease
Completed clinical trial evaluating long-haul COVID-19 and vaccine immunogenicity in patients with liver disease.
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival [NA]
This clinical trial evaluates whether adding simvastatin to carvedilol improves hepatic decompensation and survival in patients with decompe…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: The Effect of Laparoscopic Splenectomy and Azygoportal Disconnection on the Immune Function for Cirrhosis Patients [NA]
This clinical trial evaluates the effect of laparoscopic splenectomy with azygoportal disconnection on immune function in patients with live…
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CLINICAL_TRIALS trial_result · 2025-04-04Clinical Trial Update: A Study of Recombinant Human Albumin Injection to Treat Hypoalbuminemia in Cirrhotic Patients With Ascites [Phase 3]
This document provides an update on a Phase 3 trial evaluating recombinant human albumin injections to treat hypoalbuminemia in cirrhotic pa…
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Efficacy and Safety of Carvedilol in Cirrhosis Patients With Uncomplicated Ascites Without High Risk Esophageal Varices [NA]
A completed clinical trial evaluating the efficacy and safety of carvedilol in patients with cirrhosis and uncomplicated ascites without hig…
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CLINICAL_TRIALS trial_result · 2025-03-19Clinical Trial Update: The Effect of Laparoscopic Splenectomy on the Immune Function for Cirrhosis Patients [NA]
A completed clinical trial evaluating the effect of laparoscopic splenectomy on immune function in patients with cirrhosis of the liver.
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FDA approval · 2025-02-21FDA Approved: SPIRONOLACTONE — Original Application (Camber Pharmaceuticals, Inc.)
The FDA approved Camber Pharmaceuticals' original application for spironolactone, establishing a generic version of the diuretic. Spironolac…