Cirrhosis of the Liver
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Longitudinal Monitoring of Stool Characteristics
The clinical trial investigating longitudinal stool characteristics in patients with cirrhosis has completed. The snippet does not report tr…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: DOAC in Patients with Child a or B Liver Cirrhosis [Phase 2]
Phase 2 clinical trial update evaluating a direct oral anticoagulant in patients with Child-Pugh A or B cirrhosis; study status is recruitin…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: SGLT-2 Inhibitors in the Treatment of Ascites
A University of Palermo trial is evaluating SGLT-2 inhibitors as a treatment for ascites in patients with liver cirrhosis.
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CLINICAL_TRIALS research · 2024-10-10Clinical Trial Update: International Surveillance of Antimicrobial Resistance in Cirrhosis-Related Infections
An international multicenter study is evaluating antimicrobial resistance patterns in infections that occur in patients with cirrhosis. The …
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Building of Prognosis Model for Patients With Cirrhosis Based on Sarcopenia Assessed by Deep Learning
This clinical trial aims to develop a prognosis model for patients with liver cirrhosis by assessing sarcopenia through deep learning.
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CLINICAL_TRIALS research · 2024-08-05Clinical Trial Update: Ketogenic Diet in MASLD-related cACLD [NA]
Clinical trial evaluating a ketogenic diet for MASLD-related compensated advanced chronic liver disease; recruitment has not yet started.
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CLINICAL_TRIALS trial_result · 2024-06-25Clinical Trial Update: MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease
Completed clinical trial examining MERTK signalling in monocytes/macrophages in patients with liver disease.
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FDA approval · 2024-04-02FDA Approved: FUROSEMIDE — Original Application (Devatis Inc.)
FDA approved Devatis Inc.'s original application for a generic furosemide product, enabling its marketing in the United States.
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Trial of Faecal Microbiota Transplantation in Cirrhosis [Phase 3]
Phase 3 trial update for faecal microbiota transplantation in cirrhosis; study completed.
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CLINICAL_TRIALS trial_result · 2023-10-31Clinical Trial Update: Allopurinol and Quality of Life in Liver Cirrhosis [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating allopurinol for quality of life in patients with liver cirrhosis has completed.
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FDA approval · 2022-02-24FDA Approved: CHLORTHALIDONE — Original Application (TAGI Pharma, Inc.)
FDA approved the original generic application for chlorthalidone by TAGI Pharma, Inc., allowing market authorization for this thiazide-like …
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CLINICAL_TRIALS trial_result · 2021-08-31Clinical Trial Update: Evaluation of Intradermal Hepatitis B Vaccine After IMIQUIMOD's Application, in Cirrhotics Who Did Not Respond to the Usual Vaccine Regimen [Phase 2]
Phase 2 trial evaluating intradermal hepatitis B vaccine boost after IMIQUIMOD in cirrhotic patients who failed standard vaccination.
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FDA approval · 2020-07-01FDA Approved: FUROSEMIDE — Original Application (Gland Pharma Limited)
FDA approves the original generic application for furosemide from Gland Pharma Limited.
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FDA approval · 2020-05-31FDA Approved: FUROSEMIDE — Supplemental Application (Solco Healthcare LLC)
FDA approves a supplemental ANDA for furosemide from Solco Healthcare LLC.
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CLINICAL_TRIALS trial_result · 2019-10-03Clinical Trial Update: Beta-blockers for Oesophageal Varices [Phase 4]
Phase 4 clinical trial update on beta-blockers for oesophageal varices in cirrhosis patients.
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CLINICAL_TRIALS trial_result · 2019-02-11Clinical Trial Update: Effect of Beta-adrenergic Blockers on Cardiac Function, Systemic and Splanchnic Haemodynamic and Kidney Function in Cirrhotic Patiets With Refractory Ascites
This is a completed clinical trial evaluating beta-adrenergic blockers in cirrhosis with refractory ascites. It studied effects on cardiac f…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Methocarbamol in Treatment of Muscle Cramps in Cirrhotic Patients [Phase 3]
Phase 3 clinical trial update evaluating methocarbamol for treating muscle cramps in patients with cirrhosis of the liver.
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CLINICAL_TRIALS trial_result · 2018-03-08Clinical Trial Update: Evaluation Of The Portal Pressure By Doppler Ultrasound In Cirrhotic Patients Before And After Simvastatin [Phase 4]
A Phase 4 trial from Tanta University evaluating the effect of simvastatin on portal pressure in cirrhotic patients with portal hypertension…
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CLINICAL_TRIALS trial_result · 2017-11-27Clinical Trial Update: Effect of Coconut Milk Supplementation to Improve Nutritional Status in Cirrhosis Patient [NA]
This completed clinical trial evaluated whether coconut milk supplementation improves nutritional status in patients with cirrhosis.
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CLINICAL_TRIALS trial_result · 2017-11-13Clinical Trial Update: A Pharmacokinetic Study of Eltrombopag 50 Milligram (mg) in Healthy Volunteers Under Fasting Conditions [Phase 1]
Phase 1 pharmacokinetic study of eltrombopag 50 mg in healthy volunteers under fasting conditions has completed. The sponsor is GlaxoSmithKl…
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: Efficacy and Safety of Rivaroxaban in the Management of Acute Non-neoplastic PVT Compensated Cirrhosis [Phase 3]
Phase 3 clinical trial evaluating rivaroxaban for efficacy and safety in acute non-neoplastic portal vein thrombosis in compensated cirrhosi…
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CLINICAL_TRIALS trial_result · 2017-08-31Clinical Trial Update: A Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir Co-administered With Ribavirin (RBV) in Adults With Genotype 4 Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis (AGATE-1) [Phase 3]
Phase 3 AGATE-1 evaluated the safety and efficacy of Ombitasvir/Paritaprevir/Ritonavir with Ribavirin in adults with genotype 4 chronic hepa…
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CLINICAL_TRIALS research · 2017-05-31Clinical Trial Update: Platelet Indices Could Predict Spontaneous Bacterial Peritonitis in Cirrhotic Ascitic Patients
A clinical trial update exploring whether platelet indices can predict spontaneous bacterial peritonitis in patients with cirrhosis and asci…
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CLINICAL_TRIALS research · 2017-03-15Clinical Trial Update: Quality of Life Therapy for Adults With Hepatitis C Virus and Cirrhosis Awaiting Liver Transplantation [NA]
A completed clinical trial evaluated a quality-of-life therapy for adults with chronic hepatitis C and liver cirrhosis awaiting transplantat…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Dextran, a Plasma Expander, Offers New Hope for Patients With Decompensated Liver Cirrhosis and Acute Kidney Injury [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluating Dextran as a plasma expander for decompensated liver cirrhosis with acute kidney injury have completed…