Rhinosinusitis with Nasal Polyps
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CLINICAL_TRIALS trial_result · 2020-10-28Clinical Trial Update: Itraconazole for Fungal Sensitive Chronic Rhinosinusitis With Nasal Polyps [Phase 2, Phase 3]
A clinical trial update on itraconazole for fungal-sensitive chronic rhinosinusitis with nasal polyps (Phase 2/Phase 3) has been terminated;…
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 trial evaluating omalizumab in chronic rhinosinusitis with nasal polyps has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-10-23Clinical Trial Update: Controlled Clinical Study of Dupilumab in Patients With Nasal Polyps [Phase 3]
Phase 3 clinical trial of dupilumab in patients with chronic rhinosinusitis with nasal polyps completed, with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-25Clinical Trial Update: A Controlled Clinical Study of Dupilumab in Patients With Bilateral Nasal Polyps [Phase 3]
A Phase 3 clinical trial evaluating dupilumab in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) has completed and posted re…
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CLINICAL_TRIALS trial_result · 2018-12-05Clinical Trial Update: Study Evaluating the Efficacy and Safety of Intranasal Administration of 100, 200, and 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi Directional Device in Subjects With Bilateral Nasal Polyposis Followed by an 8-Week Open-Label Extension Phase to Assess Safety [Phase 3]
Phase 3 trial evaluating intranasal fluticasone propionate at multiple doses via a novel bidirectional device for bilateral nasal polyposis …
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps [Phase 2, Phase 3]
Clinical trial update reports results from Phase 2 and Phase 3 studies of the steroid-releasing S8 Sinus Implant for recurrent nasal polyps …
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: An Open-label Study to Identify Molecular Markers of Steroid Resistance [Phase 4]
This terminated open-label Phase 4 study at Massachusetts General Hospital sought to identify molecular markers of steroid resistance in nas…
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CLINICAL_TRIALS trial_result · 2018-03-30Clinical Trial Update: Nanoparticles in Nasal Mucosa
A completed clinical trial from University Hospital Ostrava studying nanoparticles applied to nasal mucosa for chronic rhinosinusitis condit…
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: Gel-Sinuplasty for Chronic Rhinosinusitis With and Without Nasal Polyposis [Phase 3]
Phase 3 clinical trial update for Gel-Sinuplasty in chronic rhinosinusitis with and without nasal polyps; current status is unknown.
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CLINICAL_TRIALS trial_result · 2018-01-09Clinical Trial Update: Doxycycline in Treating Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 2]
Phase 2 trial on doxycycline for chronic rhinosinusitis with nasal polyps was terminated; results posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-09-01Clinical Trial Update: RESPIMER® Netiflow® vs. Saline Solutions During Nasal Irrigation Following Bilateral Ethmoidectomy (Nasal Polyposis) [NA]
A completed clinical trial compared RESPIMER Netiflow nasal irrigation with saline solutions following bilateral ethmoidectomy for nasal pol…
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CLINICAL_TRIALS trial_result · 2017-06-02Clinical Trial Update: An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis [Phase 2]
Phase 2 trial update evaluating dupilumab for nasal polyposis with chronic sinusitis symptoms; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-05-19Clinical Trial Update: Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis [Phase 2]
A Phase 2 trial evaluating subcutaneous omalizumab for chronic rhinosinusitis with nasal polyps has completed and results were posted in 201…
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CLINICAL_TRIALS trial_result · 2017-05-08Clinical Trial Update: QOL Outcomes in CRS With Polyps [NA]
A University of Miami-sponsored clinical trial evaluating quality-of-life outcomes in chronic rhinosinusitis with polyps has been terminated…
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CLINICAL_TRIALS trial_result · 2017-03-27Clinical Trial Update: Study of the Efficacy of Topical Nasal Steroids Patients With Nasal Polyps
A completed clinical trial evaluated the efficacy of topical nasal steroids in patients with nasal polyps, assessing polyp size and symptom …
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CLINICAL_TRIALS trial_result · 2016-12-06Clinical Trial Update: Effect of Oral Vitamin D3 on Chronic Rhinosinusitis Treatment in Adults With Lower Vitamin D Levels [Phase 3]
A Phase 3 clinical trial is evaluating whether oral vitamin D3 improves treatment outcomes for chronic rhinosinusitis with nasal polyps in a…
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CLINICAL_TRIALS trial_result · 2016-06-01Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps [Phase 1]
Phase 1 study evaluating safety, tolerability, pharmacokinetics, and pharmacodynamics of AMG 282 in healthy subjects and patients with chron…
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CLINICAL_TRIALS trial_result · 2016-03-01Clinical Trial Update: Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps [Phase 3]
Phase 3 safety study of intranasal fluticasone propionate 400 mcg twice daily using a novel bidirectional device in chronic rhinosinusitis w…
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CLINICAL_TRIALS trial_result · 2014-10-07Clinical Trial Update: A Comparison of microRNA Samples in Patients With Nasal Polyps and Aspirin Exacerbated Respiratory Disease and Those With Nasal Polyps Only
A completed clinical trial comparing microRNA samples in patients with aspirin-exacerbated respiratory disease and nasal polyps versus those…
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CLINICAL_TRIALS trial_result · 2013-04-09Clinical Trial Update: Squamous Cell Carcinoma Antigen Analysis at the University Hospital Ostrava [NA]
A completed clinical trial at University Hospital Ostrava analyzed Squamous Cell Carcinoma Antigen in nasal polyps and related nasal conditi…
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CLINICAL_TRIALS trial_result · 2012-04-27Clinical Trial Update: Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery [NA]
Clinical trial update reports completion of a study evaluating intravenous tranexamic acid and intraoperative visualization during functiona…
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CLINICAL_TRIALS trial_result · 2011-01-07Clinical Trial Update: Biopsies and Polyps
A completed clinical trial update related to biopsies in patients with nasal polyps and asthma.
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CLINICAL_TRIALS trial_result · 2008-11-11Clinical Trial Update: Medical Polypectomy and Predictors of Response [Phase 4]
Phase 4 clinical trial evaluating medical polypectomy and predictors of response in patients with nasal polyps has completed.
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CLINICAL_TRIALS trial_result · 2007-12-28Clinical Trial Update: Double-Blind Randomized Placebo-Controlled Trial on Clinical and Biological Effects of Oral Corticosteroids or Doxycyclin in Patients With Nasal Polyposis [Phase 2]
A Phase 2 double-blind randomized placebo-controlled trial evaluated the clinical and biological effects of oral corticosteroids or doxycycl…