Rhinosinusitis with Nasal Polyps
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CLINICAL_TRIALS research · 2025-12-30Clinical Trial Update: In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps [NA]
This clinical trial update shows ongoing recruitment for a study evaluating in-clinic endoscopic polypectomy to treat chronic rhinosinusitis…
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France
The update reports an ongoing France-based study evaluating dupilumab in adults with severe chronic rhinosinusitis with nasal polyps, with t…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis [NA]
ClinicalTrials.gov entry for a study of paclitaxel-coated balloon treatment in chronic rhinosinusitis with and without nasal polyps; the tri…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Clinical Trial of TQC2731 Injection in Patients With Chronic Sinusitis and Nasal Polyps [Phase 3]
A Phase 3 clinical trial update for TQC2731 Injection in chronic rhinosinusitis with nasal polyps (CRSwNP), currently recruiting.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Evaluation of the Safety and Performance of a Bioresorbable Nasal Dressing Containing Mometasone Furoate (MF) [NA]
Clinical trial update on a bioresorbable nasal dressing containing mometasone furoate for chronic rhinosinusitis (with or without nasal poly…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: A Study to Evaluate 611 in Patients With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
A Phase 3 clinical trial evaluating 611 for chronic rhinosinusitis with nasal polyps is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Efficacy and Safety of SHR-1905 Injection in Subjects With Chronic Rhinosinusitis With Nasal Polyps [Phase 3]
Phase 3 clinical trial update for SHR-1905 injections in chronic rhinosinusitis with nasal polyps; the study is currently recruiting to asse…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Anti-IL-5 Therapy With Simple Polypectomy Versus Extended Endoscopic Sinus Surgery for CRSwNP [Phase 4]
A Phase 4 clinical trial comparing anti-IL-5 therapy with simple polypectomy versus extended endoscopic sinus surgery for chronic rhinosinus…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Tapering of Biologics in Chronic Rhinosinusitis With Nasal Polyps [Phase 4]
This Phase 4 clinical trial is investigating tapering strategies for biologics in chronic rhinosinusitis with nasal polyps and is currently …
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Implementation of a Joint Pulmonologist and ENT Consultation in the Care Pathway of Patients Suffering From Asthma and Chronic Rhinosinusitis With Nasal Polyposis: Effectiveness Compared With Consultations by Specialty (CON-PO Study). [NA]
A study analyzing a joint pulmonologist and ENT consultation pathway for asthma with chronic rhinosinusitis with nasal polyps, assessing eff…
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CLINICAL_TRIALS research · 2025-09-22Clinical Trial Update: Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis (CRS). [Phase 2, Phase 3]
Ongoing clinical trial update for a sinonasal microbiome transplant as a therapy for chronic rhinosinusitis, currently in Phase 2/3 and recr…
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CLINICAL_TRIALS research · 2025-08-07Clinical Trial Update: CRS Questionnaire Validation Project
A clinical trial update announcing recruitment for a European project to validate a questionnaire for chronic rhinosinusitis with and withou…
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CLINICAL_TRIALS research · 2025-07-18Clinical Trial Update: Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP)
The clinical trial investigates long-term outcomes of dupilumab (DUPIXENT) in adults with chronic rhinosinusitis with nasal polyps; the stud…
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Long-term Effect of Dupilumab in N-ERD
This trial update discusses the long-term effects of dupilumab in aspirin-exacerbated respiratory disease (AERD). It covers conditions such …
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Effect of Tezepelumab on Barrier Function in Severe Asthmatic Patients With and Without Comorbid Chronic Rhinosinusitis With Nasal Polyps [NA]
This clinical trial update evaluates tezepelumab’s effect on barrier function in severe asthma patients, with and without chronic rhinosinus…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: The German National CRS Registry (GenreCRS): Clinical Evaluation of the New European Academy for Allergy and Clinical Immunology (EAACI) Criteria for CRSwNP Disease Control, Remission and Cure in a Real-World Evidence Study Approach
This clinical trial registry entry describes a real-world study evaluating EAACI criteria for disease control, remission, and cure in chroni…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Olfactory Cleft Obstruction and Electrophysiological Field Potentials Predict Olfactory Restoration by Dupilumab in CRSwNP Patients.
A clinical trial update describes a study evaluating whether olfactory cleft obstruction and electrophysiological field potentials can predi…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Moving Towards Precision Medicine in United Airways Disease: Unraveling Inflammatory Patterns in Asthmatic Patients With or Without Nasal Polyps [NA]
Clinical trial update on a Medical University of Vienna study exploring precision medicine in United Airways Disease, examining inflammatory…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: Effect of Dupilumab on Nasal Epithelial Barrier Function in Patients With CRSwNP
An ongoing clinical trial is evaluating the effect of dupilumab on nasal epithelial barrier function in patients with chronic rhinosinusitis…
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CLINICAL_TRIALS research · 2025-04-16Clinical Trial Update: A Study of CM512 in Patients With Chronic Rhinosinusitis With Nasal Polyposis （NEZHA-1） [Phase 2]
A Phase 2 clinical trial evaluating CM512 in chronic rhinosinusitis with nasal polyps (NEZHA-1). The study is not yet recruiting.
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: International Severe CRSwNP Registry 2024-2028
This document is an update on the International Severe CRSwNP Registry (NCT06617754) for chronic rhinosinusitis with nasal polyps, showing t…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Mepolizumab to CRSwNP Through 12 Months - Randomised to FESS and Non-FESS Within the First 2 Weeks [Phase 4]
A Phase 4 clinical trial update for mepolizumab in chronic rhinosinusitis with nasal polyps (CRSwNP), comparing outcomes through 12 months i…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: 3D Printing to Improve Nasal Irrigation Outcome [NA]
A clinical trial sponsored by Ohio State University is evaluating whether 3D-printed nasal irrigation devices improve outcomes in chronic rh…
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CLINICAL_TRIALS research · 2025-03-18Clinical Trial Update: Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative) [NA]
A completed clinical trial (NCT03704415) investigating genomics and optimal operative treatment for chronic airway inflammation in chronic r…
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CLINICAL_TRIALS research · 2025-02-14Clinical Trial Update: Identifying Predictors Of Response To Mepolizumab In CRSwNP [Phase 4]
Phase 4 trial identifying predictors of response to mepolizumab in chronic rhinosinusitis with nasal polyps (CRSwNP). Recruitment is ongoing…