Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-10-30Clinical Trial Update: Two Step Haplo With Radiation Conditioning [Phase 2]
Phase 2 clinical trial update describing two-step haploidentical transplantation with radiation conditioning for hematologic diseases, curre…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
This trial evaluates a targeted radiopharmaceutical (211At-BC8-B10) followed by an allogeneic donor stem cell transplant for relapsed or ref…
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CLINICAL_TRIALS trial_result · 2025-10-14Clinical Trial Update: IDH2 Inhibition Using Enasidenib as Maintenance Therapy for IDH2-mutant Myeloid Neoplasms Following Allogeneic Stem Cell Transplantation [Phase 1]
A Phase 1 trial evaluates enasidenib as maintenance therapy for IDH2-mutant myeloid neoplasms after allogeneic stem cell transplantation. Th…
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CLINICAL_TRIALS other · 2025-10-14Clinical Trial Update: Study to Evaluate the Safety and Tolerability of EP0042 [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating the safety and tolerability of EP0042 from Ellipses Pharma is currently recruiting for acute myeloid leu…
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EMA approval · 2025-10-08EMA Authorised: Azacitidine Accord (azacitidine) — Accord Healthcare S.L.U.
EMA authorised Azacitidine Accord, a generic azacitidine product, for myelodysplastic syndromes and certain leukemias (acute myeloid leukemi…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: A Study of JNJ-74856665 in Participants With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) [Phase 1]
Phase 1 study of JNJ-74856665 in participants with Acute Myeloid Leukemia, Myelodysplastic Syndromes, or Chronic Myelomonocytic Leukemia has…
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CLINICAL_TRIALS research · 2025-09-29Clinical Trial Update: AZD6738 for Patients With Progressive MDS or CMML [Phase 1]
Phase 1 clinical trial update of AZD6738 in patients with progressive myelodysplastic syndrome or chronic myelomonocytic leukemia; the study…
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: NTX-301 in MDS/AML [Phase 1]
Phase 1 clinical trial update for NTX-301 in acute myeloid leukemia and myelodysplastic syndromes, including chronic myelomonocytic leukemia…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients [Phase 1]
Phase 1 trial evaluating Itacitinib with high-dose posttransplantation cyclophosphamide in older patients. The study is currently ACTIVE_NOT…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of Tuspetinib (HM43239) in patients…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML [Phase 2]
Phase 2 clinical trial evaluating a metabolically optimized, non-cytotoxic, low-dose weekly decitabine/venetoclax regimen in myelodysplastic…
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Pacritinib in CMML [Phase 1, Phase 2]
Clinical trial update indicating Pacritinib is being studied for Chronic Myelomonocytic Leukemia in Phase 1/Phase 2 and is currently recruit…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: The Kinetics Profiling of Immune Reconstitution and Clinical Outcomes
Clinical trial update on the kinetics profiling of immune reconstitution and clinical outcomes in chronic myelomonocytic leukemia; the study…
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Haplo Peripheral Blood Sct In GVHD Prevention [Phase 1]
Phase 1 trial update reporting the completion of a haploidentical peripheral blood stem cell transplantation approach for the prevention of …
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: CPX-351 as a Novel Approach for the Treatment of Older Patients With AML and MDS [Phase 2]
Phase 2 trial status update for CPX-351 in older patients with refractory or relapsed acute myeloid leukemia and myelodysplastic syndromes; …
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CLINICAL_TRIALS trial_result · 2025-07-14Clinical Trial Update: AMG 176 With Azacitidine in Subjects With Myelodysplastic Syndrome /Chronic Myelomonocytic Leukemia [Phase 1]
A Phase 1 study evaluating AMG 176 in combination with azacitidine in higher-risk myelodysplastic syndromes and chronic myelomonocytic leuke…
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CLINICAL_TRIALS other · 2025-07-10Clinical Trial Update: FHD-286 as Monotherapy or Combination Therapy in Subjects With Advanced Hematologic Malignancies [Phase 1]
Phase 1 trial update for FHD-286 as monotherapy or in combination in adults with advanced hematologic malignancies. The study is currently a…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Eltrombopag as a Novel Therapeutic Approach for Low-risk MDS and CMML With TET2 Mutations [Phase 2]
Phase 2 clinical trial evaluating eltrombopag as a treatment for low-risk Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia with…
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations [Phase 1]
Phase 1 study of oral LY3410738 in patients with IDH1/IDH2-mutant hematologic malignancies is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-06-27Clinical Trial Update: Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning [Phase 2]
Phase 2 trial evaluating vedolizumab with post-transplant cyclophosphamide and tacrolimus to prevent graft-versus-host disease in patients u…
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CLINICAL_TRIALS trial_result · 2025-06-22Clinical Trial Update: A Study of E7820 in People With Bone Marrow (Myeloid) Cancers [Phase 2]
Phase 2 study of E7820 in people with bone marrow (myeloid) cancers, including Acute Myeloid Leukemia, Myelodysplastic Syndromes, and Chroni…
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CLINICAL_TRIALS research · 2025-06-10Clinical Trial Update: Oral-ATO for TP53-mutated Myeloid Malignancies [Phase 2]
A Phase 2 clinical trial evaluating oral arsenic trioxide for TP53-mutated myeloid malignancies, including acute myeloid leukemia and myelod…
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CLINICAL_TRIALS research · 2025-06-04Clinical Trial Update: ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis [Phase 2]
A Phase 2 trial (ABBA CORD) evaluating donor-derived cord blood T cells with abatacept for prophylaxis of acute graft-versus-host disease in…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Adding Itacitinib to Cyclophosphamide and Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Hematopoietic Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update describing the addition of itacitinib to cyclophosphamide and tacrolimus for preventing graft-versus-host dise…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Study of Tagraxofusp for Post-Transplant Maintenance for Patients With CD 123+ AML, MDS, MF and CMML (HSCT 002) [Phase 1]
An early-phase clinical trial evaluating Tagraxofusp as post-transplant maintenance in patients with CD123-positive acute myeloid leukemia, …