Myelomonocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Quizartinib With Azacitidine or Cytarabine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 1, Phase 2]
Phase 1/2 trial evaluating quizartinib with azacitidine or cytarabine in relapsed or refractory acute myeloid leukemia and myelodysplastic s…
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CLINICAL_TRIALS trial_result · 2024-02-15Clinical Trial Update: Chemotherapy in Treating Patients With Myelodysplastic Syndrome Before Donor Stem Cell Transplant [Phase 2]
Phase 2 trial evaluating chemotherapy in patients with myelodysplastic syndromes prior to donor stem cell transplantation has completed with…
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CLINICAL_TRIALS trial_result · 2024-02-01Clinical Trial Update: A Study of APG-115 Alone or Combined With Azacitidine in Patients With AML, CMML, or MDS [Phase 1, Phase 2]
Clinical trial update on APG-115 alone or with azacitidine in patients with AML, CMML, or MDS across Phase 1 and Phase 2.
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CLINICAL_TRIALS trial_result · 2023-12-18Clinical Trial Update: Continuation Study of B1371019(NCT03416179) and B1371012(NCT02367456) Evaluating Azacitidine With Or Without Glasdegib In Patients With Previously Untreated AML, MDS or CMML [Phase 3]
Phase 3 continuation study of azacitidine with or without glasdegib in untreated AML, MDS, or CMML; trial completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-10-27Clinical Trial Update: 5-azacytidine Treatment Versus 5-azacytidine Followed by Allogeneic Stem Cell Transplantation in Elderly Patients With Myelodysplastic Syndrome (MDS) [Phase 2]
Phase 2 clinical trial comparing 5-azacytidine alone versus 5-azacytidine followed by allogeneic stem cell transplantation in elderly patien…
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CLINICAL_TRIALS trial_result · 2023-10-24Clinical Trial Update: HCT With PTCy in Higher-risk MDS [Phase 2]
Phase 2 clinical trial evaluating haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide in higher-risk mye…
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CLINICAL_TRIALS trial_result · 2023-10-17Clinical Trial Update: Ruxolitinib for the Treatment of Chronic Myelomonocytic Leukemia (CMML): A Phase 2 Expansion [Phase 2]
This entry details a Phase 2 expansion study of ruxolitinib for chronic myelomonocytic leukemia, with results posted in October 2023.
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: Methods of T Cell Depletion Trial (MoTD) [Phase 2]
Phase 2 trial update for methods of T cell depletion in various hematologic malignancies is ongoing.
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Salsalate, Venetoclax, and Decitabine or Azacitidine for the Treatment of Acute Myeloid Leukemia or Advanced Myelodysplasia/Myeloproliferative Disease [Phase 2]
Phase 2 clinical trial investigating salsalate, venetoclax, and decitabine or azacitidine for acute myeloid leukemia and advanced myelodyspl…
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CLINICAL_TRIALS trial_result · 2023-05-18Clinical Trial Update: Guadecitabine (SGI-110) vs Treatment Choice in Adults With MDS or CMML Previously Treated With HMAs [Phase 3]
Phase 3 trial evaluating guadecitabine (SGI-110) vs treatment choice in adults with myelodysplastic syndromes or chronic myelomonocytic leuk…
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CLINICAL_TRIALS trial_result · 2023-04-04Clinical Trial Update: Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia [Phase 2]
Phase 2 trial evaluating Clofarabine plus Melphalan as a conditioning regimen before donor stem cell transplantation for patients with myelo…
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CLINICAL_TRIALS trial_result · 2023-02-09Clinical Trial Update: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome [Phase 1]
Phase 1 trial of a conditioning regimen including an iodine-131 labeled monoclonal antibody with fludarabine, cyclophosphamide, total-body i…
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CLINICAL_TRIALS trial_result · 2022-11-03Clinical Trial Update: Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malignancies [Phase 2]
Phase 2 clinical trial update on shorter course tacrolimus after non-myeloablative conditioning with related donor PBSCT and high-dose postt…
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CLINICAL_TRIALS trial_result · 2022-09-22Clinical Trial Update: Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine as First-Line Treatment for Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML), or Low-Blast Acute Myelogenous Leukemia (AML) [Phase 3]
This Phase 3 trial compares pevonedistat plus azacitidine versus azacitidine alone as first-line therapy for higher-risk myelodysplastic syn…
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CLINICAL_TRIALS trial_result · 2022-08-01Clinical Trial Update: Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Total Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine and Mycophenolate Mofetil in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome [Phase 2]
Phase 2 clinical trial evaluating a combined regimen including iodine-131 monoclonal antibody BC8, fludarabine phosphate, total body irradia…
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CLINICAL_TRIALS trial_result · 2022-03-15Clinical Trial Update: Azacytidine + HAG Regimen vs. Azacytidine for Elderly Patients With Newly Diagnosed Myeloid Malignancy [Phase 4]
Clinical trial comparing azacitidine plus HAG regimen versus azacitidine in elderly patients with newly diagnosed myeloid malignancies; phas…
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CLINICAL_TRIALS trial_result · 2022-01-04Clinical Trial Update: Therapy of HES, PV, Atypical Chronic Myelocytic Leukemia (CML) or Chronic Myelomonocytic Leukemia (CMML), and Mastocytosis With Imatinib Mesylate [NA]
Clinical trial update of imatinib mesylate for various myeloproliferative and related neoplasms including CMML, CML, polycythemia vera, hype…
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CLINICAL_TRIALS trial_result · 2021-10-04Clinical Trial Update: Targeted Therapy in Treating Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia [Phase 2]
Phase 2 trial update on a targeted therapy for relapsed/refractory acute lymphoblastic leukemia and acute myeloid leukemia; trial status ter…
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CLINICAL_TRIALS trial_result · 2021-07-08Clinical Trial Update: Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia [Phase 3]
Phase 3 clinical trial evaluating lenalidomide with or without epoetin alfa for myelodysplastic syndrome and associated anemia, with results…
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: Phase II Part 2 Expansion of Oral Rigosertib in Combination With Azacitidine [Phase 1, Phase 2]
Phase II extension study of oral rigosertib in combination with azacitidine in myelodysplastic syndrome and related conditions has completed…
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CLINICAL_TRIALS trial_result · 2021-06-11Clinical Trial Update: Total Body Irradiation +/- Total Lymphoid Irradiation & Anti-Thymocyte Globulin in Non-myeloablative Hematopoietic Cell Transplantation [Phase 2]
Phase 2 trial update on Total Body Irradiation with or without Total Lymphoid Irradiation and Anti-Thymocyte Globulin in non-myeloablative h…
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CLINICAL_TRIALS trial_result · 2021-05-19Clinical Trial Update: Leukemia SPORE Phase II DAC Study for R/R and Elderly Acute AML and MDS [Phase 2]
Phase II trial update for DAC in relapsed/refractory and elderly patients with acute myeloid leukemia and myelodysplastic syndrome.
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: A Study of Eltrombopag in Patients With CMML and Thrombocytopenia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating eltrombopag in CMML patients with thrombocytopenia has completed.
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CLINICAL_TRIALS trial_result · 2021-03-05Clinical Trial Update: A Combination Study of PF-04449913 (Glasdegib) and Azacitidine In Untreated MDS, AML and CMML Patients [Phase 1]
A Phase 1 trial evaluating the combination of glasdegib (PF-04449913) with azacitidine in untreated myelodysplastic syndrome, acute myeloid …
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CLINICAL_TRIALS trial_result · 2021-02-25Clinical Trial Update: Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms [Phase 1, Phase 2]
Phase 1b/2 trial assessing APR-246 plus azacitidine in TP53-mutant myeloid neoplasms completed with posted results.