Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-09-20Clinical Trial Update: A Phase II Study of Gleevec and Arsenic Trioxide in Patients With CML Who Fail Gleevec [Phase 2]
Phase II trial evaluating the combination of imatinib (Gleevec) and arsenic trioxide in chronic myeloid leukemia patients who failed prior G…
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CLINICAL_TRIALS trial_result · 2011-08-31Clinical Trial Update: Vaccine Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
A phase 2 trial evaluating a vaccine therapy for chronic phase chronic myeloid leukemia was terminated; results were posted in 2011.
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CLINICAL_TRIALS withdrawal · 2011-08-26Clinical Trial Update: Expanded Access Program of AMN107 in Imatinib-resistant or Intolerant Adult Patients With Chronic Myeloid Leukemia
Expanded access program for nilotinib (AMN107) in adults with imatinib-resistant or intolerant chronic myeloid leukemia has ended; the progr…
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CLINICAL_TRIALS trial_result · 2011-08-02Clinical Trial Update: Flu,Alemtuzumab,and TBI Followed By Donor Stem Cell Chronic Phase CML [Phase 2]
Phase 2 trial update for flu/Alemtuzumab/TBI followed by donor stem cell transplant in chronic myeloid leukemia in chronic phase; study term…
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Interferon Alfa Plus Sargramostim in Treating Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 trial evaluating the combination of Interferon alfa and sargramostim in newly diagnosed chronic-phase chronic myeloid leukemia has…
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CLINICAL_TRIALS trial_result · 2011-07-20Clinical Trial Update: Sargramostim Following Allogeneic Bone Marrow Transplantation in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 trial evaluating sargramostim after allogeneic bone marrow transplantation in patients with chronic myeloid leukemia was terminate…
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CLINICAL_TRIALS trial_result · 2011-07-13Clinical Trial Update: Oral Nilotinib in Adults With Chronic Myeloid Leukemia (CML) in Blast Crisis Who Are Imatinib Resistant or Intolerant
This clinical trial update concerns the use of oral nilotinib for adults with chronic myeloid leukemia in blast crisis who are resistant or …
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CLINICAL_TRIALS trial_result · 2011-07-07Clinical Trial Update: Study of Dasatinib in Patients With Chronic Phase Chronic Myeloid Leukemia and a Suboptimal Response to Imatinib [Phase 2]
Phase 2 trial of dasatinib in patients with chronic phase chronic myeloid leukemia who had suboptimal responses to imatinib; the study was t…
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CLINICAL_TRIALS trial_result · 2011-06-07Clinical Trial Update: BMS-354825 or Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia That Did Not Respond to Previous Imatinib Mesylate [Phase 2]
Phase 2 trial evaluating dasatinib (BMS-354825) in patients with chronic phase chronic myeloid leukemia who did not respond to prior imatini…
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Nilotinib vs Imatinib in Adult Patients With Philadelphia (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) [Phase 3]
A Phase 3 trial comparing nilotinib to imatinib in adults with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase wa…
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CLINICAL_TRIALS trial_result · 2011-05-04Clinical Trial Update: Interleukin 11, Thrombocytopenia, Imatinib in Chronic Myelogenous Leukemia (CML) Patients [Phase 2]
Phase 2 trial evaluating interleukin-11 to address thrombocytopenia in chronic myeloid leukemia patients treated with imatinib. The study ha…
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CLINICAL_TRIALS withdrawal · 2011-04-28Clinical Trial Update: Allogeneic Tumor Cell Vaccination in Patients With Chronic Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 trial evaluating an allogeneic tumor cell vaccine for chronic myeloid leukemia was withdrawn.
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CLINICAL_TRIALS trial_result · 2011-04-19Clinical Trial Update: Chronic Myelogenous Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemic Study [Phase 1]
Phase 1 trial conducted by Bristol-Myers Squibb in chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemi…
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CLINICAL_TRIALS trial_result · 2011-04-14Clinical Trial Update: Dasatinib (BMS-354825) in Subjects With Lymphoid Blast Phase Chronic Myeloid Leukemia or Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia [Phase 2]
A Phase 2 clinical trial evaluated dasatinib in lymphoid blast phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lym…
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CLINICAL_TRIALS trial_result · 2011-04-14Clinical Trial Update: Reduced Intensity AlloSCT in(CML) With Persistent Disease [Phase 2]
A Phase 2 trial evaluating reduced-intensity allogeneic stem cell transplantation for chronic myeloid leukemia with persistent disease has b…
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CLINICAL_TRIALS trial_result · 2011-04-05Clinical Trial Update: Dasatinib in Imatinib Resistant/Intolerant Chinese CML (Chronic and Advanced Phase) Subjects [Phase 2]
Phase 2 trial update evaluating dasatinib in imatinib-resistant or intolerant Chinese chronic myeloid leukemia patients, completed with resu…
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CLINICAL_TRIALS trial_result · 2011-03-29Clinical Trial Update: Impact of the Inhibitors of Tyrosine Kinase on the Male Fertility [NA]
This clinical trial update assesses how tyrosine kinase inhibitors affect male fertility in patients with chronic myeloid leukemia or gastro…
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CLINICAL_TRIALS trial_result · 2011-03-15Clinical Trial Update: A Phase III Study of Dasatinib vs Imatinib in Patients With Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia [Phase 3]
Phase III trial comparing dasatinib to imatinib in newly diagnosed chronic-phase chronic myeloid leukemia; results were posted in 2011. The …
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CLINICAL_TRIALS trial_result · 2011-03-08Clinical Trial Update: Irinotecan and Cytarabine in Treating Patients With Refractory or Recurrent Acute Myeloid Leukemia or Chronic Myelogenous Leukemia [Phase 1]
Phase 1 study evaluating irinotecan and cytarabine in patients with refractory or recurrent acute myeloid leukemia or chronic myeloid leukem…
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Synthetic Vaccine in Patients With Chronic Myeloid Leukemia and Minimal Residual Disease [Phase 2]
Phase 2 trial of a synthetic vaccine in patients with chronic myeloid leukemia and minimal residual disease has completed and results were p…
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EMA withdrawal · 2011-01-31EMA Application withdrawn: Tekinex (omacetaxine mepesuccinate) — ChemGenex Europe SAS
EMA withdrew the Tekinex application for omacetaxine mepesuccinate (ChemGenex Europe SAS) for chronic myeloid leukemia with BCR-ABL positive…
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FDA approval · 2011-01-14FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Tasigna (nilotinib) by Novartis Pharmaceuticals to modify labeling and/or expand its approved in…
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CLINICAL_TRIALS trial_result · 2010-11-30Clinical Trial Update: A Study of Dasatinib in Chronic Phase Philadelphia Chromosome Positive Chronic Myeloid Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial of dasatinib in patients with chronic phase Philadelphia chromosome-positive chronic myeloid leukemia has completed…
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FDA approval · 2010-10-28FDA Approved: DASATINIB — Supplemental Application (Prasco Laboratories)
FDA approved a supplemental application for dasatinib filed by Prasco Laboratories.
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CLINICAL_TRIALS trial_result · 2010-10-25Clinical Trial Update: A Study Comparing Imatinib and Imatinib/Pegylated Interferon in Chronic Myeloid Leukemia [Phase 2]
A Phase 2 study comparing Imatinib alone versus Imatinib plus pegylated interferon in chronic myeloid leukemia has completed.