Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Chemotherapy With Cordycepin Plus Pentostatin in Treating Patients With Refractory Acute Lymphocytic or Chronic Myelogenous Leukemia [Phase 1]
Phase 1 trial update evaluating cordycepin plus pentostatin in patients with refractory acute lymphoblastic leukemia or chronic myeloid leuk…
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Bone Marrow Transplantation in Treating Patients With Multiple Myeloma, Chronic Phase Chronic Myelogenous Leukemia, or Agnogenic Myeloid Metaplasia [Phase 2]
Phase 2 clinical trial update on bone marrow transplantation for patients with multiple myeloma, chronic myeloid leukemia (chronic phase), o…
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Safety Assessment of a Multipeptide-gene Vaccine in CML [Phase 1]
This Phase 1 clinical trial update reports safety assessment data for a multipeptide-gene vaccine in chronic myeloid leukemia.
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CLINICAL_TRIALS trial_result · 2012-06-04Clinical Trial Update: Unrelated Double Umbilical Cord Blood Units Transplantation [Phase 2, Phase 3]
Update on a Phase 2/3 trial evaluating unrelated double umbilical cord blood transplantation for acute and chronic leukemias, sponsored by T…
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CLINICAL_TRIALS trial_result · 2012-05-28Clinical Trial Update: Arsenic Trioxide and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia [Phase 1, Phase 2]
This clinical trial update summarizes results from a Phase 1/2 study evaluating arsenic trioxide in combination with imatinib mesylate for c…
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CLINICAL_TRIALS trial_result · 2012-05-15Clinical Trial Update: Paclitaxel in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating paclitaxel in patients with refractory or recurrent acute leukemia or chronic myelogenous leukemia has…
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CLINICAL_TRIALS withdrawal · 2012-05-10Clinical Trial Update: Palifermin After Haploidentical PBSCT [Phase 2]
A Phase 2 trial evaluating palifermin after haploidentical peripheral blood stem cell transplantation has been withdrawn.
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CLINICAL_TRIALS trial_result · 2012-04-06Clinical Trial Update: Safety and Efficacy of Unrelated Cord Blood Transplantation for Adult Patients With Hematologic Malignancies [Phase 1, Phase 2]
This clinical trial update reports safety and early efficacy data for unrelated cord blood transplantation in adults with hematologic malign…
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CLINICAL_TRIALS trial_result · 2012-03-16Clinical Trial Update: CD8+ T Cell Depletion for GVHD Prophylaxis After Peripheral Blood Stem Cell Transplantation [NA]
This clinical trial update reports on a study evaluating CD8+ T cell depletion as prophylaxis against graft-versus-host disease after periph…
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CLINICAL_TRIALS trial_result · 2012-03-13Clinical Trial Update: Glivec/Gleevec Pediatric (Age 1 to Less Than 4) PK Study in CML, Ph+ ALL Patients and Other Glivec/Gleevec® Indicated Hematological Disorders. [Phase 1]
A pediatric pharmacokinetic study of Glivec/Gleevec (imatinib) in children aged 1 to less than 4 with chronic myeloid leukemia, Philadelphia…
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CLINICAL_TRIALS research · 2012-02-29Clinical Trial Update: Registration of Children With CML and Treatment With Imatinib
This update describes the registration of children with chronic myeloid leukemia in a study evaluating treatment with imatinib. The current …
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CLINICAL_TRIALS trial_result · 2012-02-03Clinical Trial Update: Efficacy of 400 Mg Versus 800 Mg Imatinib in Chronic Myeloid Leukemia in Chronic Phase Patients - TOPS (Tyrosine Kinase Inhibitor Optimization and Selectivity) [Phase 3]
Phase 3 TOPS trial comparing 400 mg versus 800 mg imatinib in chronic-phase chronic myeloid leukemia was terminated; results were posted in …
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FDA label_change · 2012-01-26FDA Approved: DROXIA — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for DROXIA (hydroxyurea) from Waylis Therapeutics LLC, indicating a label change/expansion. The docu…
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CLINICAL_TRIALS trial_result · 2012-01-26Clinical Trial Update: Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation [Phase 2]
A Phase 2 study evaluating sirolimus with tacrolimus for graft-versus-host disease prophylaxis after unrelated donor stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2012-01-20Clinical Trial Update: PTK 787 and Gleevec in Patients With AML, AMM, and CML-BP [Phase 1, Phase 2]
This clinical trial update reports Phase 1/Phase 2 results for the combination of PTK 787 and imatinib (Gleevec) in patients with acute myel…
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CLINICAL_TRIALS trial_result · 2012-01-05Clinical Trial Update: Safety Study of MultiStem® in Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplasia [Phase 1]
This Phase 1 safety study of MultiStem in patients with acute myeloid leukemia, chronic myeloid leukemia, or myelodysplastic syndromes has c…
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CLINICAL_TRIALS research · 2011-12-13Clinical Trial Update: Prospective Database for Chronic Myelogenous Leukemia [NA]
A prospective database update for chronic myeloid leukemia is being conducted, sponsored by King Faisal Specialist Hospital & Research Cente…
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CLINICAL_TRIALS trial_result · 2011-12-07Clinical Trial Update: Efficacy and Safety Study of Dasatinib in Patients With Chronic Myeloid Leukemia [Phase 2]
Phase 2 efficacy and safety study of dasatinib in Chronic myeloid leukemia has been terminated.
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Bioequivalence And Food Effect Study Of Bosutinib In Healthy Subjects [Phase 1]
Pfizer completed a Phase 1 bioequivalence and food-effect study of bosutinib in healthy subjects to support its use in Philadelphia chromoso…
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CLINICAL_TRIALS trial_result · 2011-11-30Clinical Trial Update: Imatinib Mesylate With or Without Hydroxychloroquine in Treating Patients With Chronic Myeloid Leukemia [Phase 2]
Phase 2 trial evaluating imatinib mesylate with or without hydroxychloroquine in chronic myeloid leukemia; the current status is unknown.
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FDA label_change · 2011-11-18FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for TASIGNA (nilotinib) from Novartis Pharmaceuticals Corporation, resulting in changes to the drug'…
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: Fludarabine and Radiation Therapy in Treating Patients Who Are Undergoing Donor Stem Cell Transplant for Chronic Phase or Accelerated Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating fludarabine with radiation therapy prior to donor stem cell transplantation for chronic myeloid leukemia in chronic…
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CLINICAL_TRIALS trial_result · 2011-11-07Clinical Trial Update: Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for CML Patients [Phase 2]
Phase 2 trial of Imatinib Mesylate, Busulfan, Fludarabine, and Antithymocyte Globulin for chronic myeloid leukemia was terminated with resul…
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CLINICAL_TRIALS research · 2011-11-03Clinical Trial Update: Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia in Japan
This entry provides a clinical trial update on dasatinib in newly diagnosed chronic-phase chronic myeloid leukemia in Japan. The status of t…
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CLINICAL_TRIALS trial_result · 2011-11-02Clinical Trial Update: Autologous Transplantation for Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluating autologous stem cell transplantation for chronic myeloid leukemia has completed.