Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2010-09-21Clinical Trial Update: Fludarabine, Total-Body Irradiation, and Donor Stem Cell Transplant Followed By Cyclosporine and Mycophenolate Mofetil in Treating Patients With Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial using fludarabine, total-body irradiation conditioning followed by donor stem cell transplant and post-transplant…
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CLINICAL_TRIALS trial_result · 2010-08-09Clinical Trial Update: High-Dose Busulfan and High-Dose Cyclophosphamide Followed By Donor Bone Marrow Transplant in Treating Patients With Leukemia, Myelodysplastic Syndrome, Multiple Myeloma, or Recurrent Hodgkin or Non-Hodgkin Lymphoma [Phase 2]
A Phase 2 trial evaluating high-dose busulfan and high-dose cyclophosphamide conditioning followed by donor bone marrow transplantation in p…
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CLINICAL_TRIALS trial_result · 2010-06-10Clinical Trial Update: Fludarabine/Carboplatin/Topotecan w/Thalidomide for Relapsed/Refractory AML, CML and MDS [Phase 2]
A Phase 2 clinical trial evaluating the combination of fludarabine, carboplatin, topotecan, and thalidomide in relapsed/refractory acute mye…
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CLINICAL_TRIALS trial_result · 2010-05-06Clinical Trial Update: Clofarabine and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia, or Myeloproliferative Disorders [Phase 1]
Phase 1 trial evaluating the combination of clofarabine and cyclophosphamide in patients with relapsed or refractory acute leukemia, chronic…
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CLINICAL_TRIALS trial_result · 2010-04-02Clinical Trial Update: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
This clinical trial update summarizes a Phase 2 study evaluating combination chemotherapy followed by peripheral stem cell transplantation i…
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CLINICAL_TRIALS trial_result · 2010-03-30Clinical Trial Update: Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myeloid Leukemia [Phase 3]
A Phase 3 clinical trial evaluating bone marrow or peripheral stem cell transplantation for patients with chronic myeloid leukemia has compl…
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FDA approval · 2010-03-15FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Tasigna (nilotinib) filed by Novartis Pharmaceuticals Corporation. The approval updates the …
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Dasatinib (BMS-354825) in Subjects With Myeloid Blast Phase Chronic Myeloid Leukemia Resistant to or Intolerant of Imatinib Mesylate [Phase 2]
Phase 2 trial evaluating dasatinib in patients with chronic myeloid leukemia in blast crisis who were resistant or intolerant to imatinib; t…
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CLINICAL_TRIALS trial_result · 2010-03-02Clinical Trial Update: Study of Dasatinib (BMS-354825) in Patients With Accelerated Phase Chronic Myeloid Leukemia [Phase 2]
This Phase 2 clinical trial reports results for dasatinib in patients with accelerated-phase chronic myeloid leukemia, with the study comple…
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CLINICAL_TRIALS trial_result · 2010-02-24Clinical Trial Update: Study of BMS-354825 (Dasatinib) in Patients With Chronic Myeloid Leukemia Who Are Either Resistant or Intolerant to Imatinib [Phase 2]
A Phase 2 study evaluated dasatinib in patients with chronic myeloid leukemia that is resistant or intolerant to imatinib; results from the …
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CLINICAL_TRIALS trial_result · 2010-02-08Clinical Trial Update: A Study of Dasatinib in Patients With Chronic Myelogenous Leukemia Who Are Resistant or Intolerant of Imatinib Mesylate [Phase 2]
Phase 2 study of dasatinib in chronic myeloid leukemia patients resistant or intolerant to imatinib has completed.
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CLINICAL_TRIALS trial_result · 2010-01-07Clinical Trial Update: Dasatinib (BMS-354835) Versus Imatinib Mesylate in Subjects With Chronic Myeloid Leukemia [Phase 2]
Phase 2 trial comparing dasatinib to imatinib in chronic myeloid leukemia completed with results posted in 2010.
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: Peripheral Blood (PB) Versus Bone Marrow (BM) in Allogeneic Stem Cell Transplantation [Phase 3]
This Phase 3 trial comparing peripheral blood versus bone marrow as graft sources in allogeneic stem cell transplantation has completed. It …
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CLINICAL_TRIALS trial_result · 2009-11-23Clinical Trial Update: Efficacy, Safety and Long-term Prognosis of Imatinib in Patients Newly Diagnosed With Chronic Myelogenous Leukemia (Chronic Phase) [Phase 3]
Phase 3 trial update showing the efficacy, safety and long-term prognosis of imatinib in patients with newly diagnosed chronic-phase chronic…
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CLINICAL_TRIALS trial_result · 2009-11-23Clinical Trial Update: Gleevec Trial in Patients With Newly Diagnosed Chronic Phase Chronic Myelogenous Leukemia [Phase 4]
ClinicalTrials.gov indicates completion of a Phase 4 trial of imatinib (Gleevec) in patients with newly diagnosed chronic phase chronic myel…
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CLINICAL_TRIALS trial_result · 2009-10-14Clinical Trial Update: Phase II Trial of Decitabine in Patients With Chronic Myelogenous Leukemia Chronic Phase Who Are Refractory to Imatinib Mesylate (Gleevec) [Phase 2]
A Phase II clinical trial evaluating decitabine in patients with chronic-phase chronic myeloid leukemia refractory to imatinib mesylate (Gle…
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CLINICAL_TRIALS trial_result · 2009-09-03Clinical Trial Update: A Study of Dasatinib vs. High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed to Achieve Complete Cytogenetic Response After 3-18 Months of Imatinib Therapy [Phase 3]
A Phase 3 trial comparing dasatinib to high-dose imatinib in chronic phase CML patients who failed to achieve complete cytogenetic response …
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FDA approval · 2009-08-21FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
The FDA approved a supplemental application for Tasigna (nilotinib) submitted by Novartis, resulting in updated labeling.
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CLINICAL_TRIALS trial_result · 2009-08-18Clinical Trial Update: T-cell and B-cell Depletion in Allogeneic Peripheral Blood Stem Cell Transplantation [Phase 3]
A Phase 3 trial investigating T-cell and B-cell depletion in allogeneic peripheral blood stem cell transplantation has been terminated.
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CLINICAL_TRIALS trial_result · 2009-08-11Clinical Trial Update: Clinical Trial to Evaluate the Safety and Efficacy of Treosulfan Based Conditioning Prior to Allogeneic Haematopoietic Stem Cell Transplantation (HSCT) [Phase 2]
Phase 2 clinical trial evaluating treosulfan-based conditioning prior to allogeneic hematopoietic stem cell transplantation, focusing on saf…
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CLINICAL_TRIALS trial_result · 2009-07-16Clinical Trial Update: Study Evaluating The Pharmacokinetics (PK) And Safety Of Bosutinib In Subjects With Liver Disease And In Healthy Subjects [Phase 1]
Phase 1 study assessing the pharmacokinetics and safety of bosutinib in subjects with liver disease and in healthy controls.
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CLINICAL_TRIALS trial_result · 2009-06-01Clinical Trial Update: Safety and Tolerability Study of INNO-406 to Treat Chronic Myeloid Leukemia or Acute Lymphocytic Leukemia [Phase 1]
A Phase 1 safety and tolerability study of INNO-406 for chronic myeloid leukemia and acute lymphoblastic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2009-03-03Clinical Trial Update: The Randomized Study of Dasatinib and High-Dose Imatinib (600mg) in Suboptimal Responder
This document reports on a randomized study evaluating dasatinib in combination with high-dose imatinib (600 mg) for suboptimal responders w…
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CLINICAL_TRIALS trial_result · 2009-02-18Clinical Trial Update: Use of SV40 Vectors to Treat Chronic Myeloid Leukemia (CML)
A clinical trial evaluating SV40 vector-based therapy for chronic myeloid leukemia has completed. The study was sponsored by Hadassah Medica…
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CLINICAL_TRIALS trial_result · 2009-02-13Clinical Trial Update: Haploidentical Stem Cell Transplant for Treatment Refractory Hematological Malignancies [Phase 2]
A Phase 2 clinical trial from St. Jude evaluated haploidentical hematopoietic stem cell transplantation for treatment-refractory hematologic…