Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2013-01-07Clinical Trial Update: Vaccine Therapy Plus Immune Adjuvant in Treating Patients With Chronic Myeloid Leukemia, Acute Myeloid Leukemia, or Myelodysplastic Syndrome [Phase 1, Phase 2]
This update summarizes a Phase 1/2 clinical trial of a vaccine therapy with an immune adjuvant in patients with chronic myeloid leukemia, ac…
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FDA approval · 2012-12-20FDA Approved: TASIGNA — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for Tasigna (nilotinib) submitted by Novartis Pharmaceuticals Corporation. The action typically upda…
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CLINICAL_TRIALS trial_result · 2012-12-17Clinical Trial Update: Sibling and Unrelated Donor Hematopoietic Cell Transplant in Hematologic Malignancies [NA]
A completed clinical trial evaluating hematopoietic cell transplantation from sibling and unrelated donors in patients with hematologic mali…
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FDA approval · 2012-12-14FDA Approved: ICLUSIG — Original Application (Takeda Pharmaceuticals America, Inc.)
This FDA page documents the original approval of ICLUSIG (ponatinib hydrochloride) by Takeda Pharmaceuticals America, Inc.
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CLINICAL_TRIALS trial_result · 2012-12-07Clinical Trial Update: Study of Parathyroid Hormone Following Sequential Cord Blood Transplantation From an Unrelated Donor [Phase 2]
Phase 2 study evaluating parathyroid hormone after sequential cord blood transplantation from an unrelated donor; the trial was terminated a…
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CLINICAL_TRIALS withdrawal · 2012-11-19Clinical Trial Update: Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Chronic Myelogenous Leukemia [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating combination chemotherapy followed by peripheral stem cell transplantation for chronic myeloid leukemia…
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CLINICAL_TRIALS trial_result · 2012-11-05Clinical Trial Update: Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML [Phase 3]
Phase 3 clinical trial comparing bosutinib to imatinib in newly diagnosed chronic phase Philadelphia chromosome–positive chronic myeloid leu…
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CLINICAL_TRIALS trial_result · 2012-10-19Clinical Trial Update: Bendamustine in Acute Leukemia and MDS [Phase 1, Phase 2]
Phase 1/2 trial of bendamustine in acute leukemia and myelodysplastic syndromes was terminated with results posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-09-07Clinical Trial Update: AG-858 in Patients Who Are Cytogenetically Positive After Treatment With Gleevec™ [Phase 2]
This report updates a Phase 2 trial of AG-858 in patients with chronic myeloid leukemia who remain cytogenetically positive after treatment …
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FDA approval · 2012-09-04FDA Approved: BOSULIF — Original Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved BOSULIF (bosutinib) from Pfizer for adults with Philadelphia chromosome-positive chronic myeloid leukemia (CML) with resistance…
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CLINICAL_TRIALS trial_result · 2012-08-29Clinical Trial Update: Safety and Efficacy of Imatinib in Chronic Myelogenous Patients in Relapse After Stem Cell Transplantation [Phase 2]
Phase 2 trial evaluating safety and efficacy of imatinib in chronic myeloid leukemia patients who relapse after stem cell transplantation. T…
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CLINICAL_TRIALS trial_result · 2012-08-23Clinical Trial Update: CD8 DLI for Patients With Relapse or Residual Disease Following Allogeneic Stem Cell Transplantation [NA]
This clinical trial evaluated CD8 donor lymphocyte infusion for relapse or residual disease after allogeneic stem cell transplantation. The …
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CLINICAL_TRIALS trial_result · 2012-08-20Clinical Trial Update: Imatinib Mesylate and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
Phase 2 study evaluating imatinib mesylate in combination with interferon alfa for chronic myeloid leukemia was terminated; results were pos…
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CLINICAL_TRIALS trial_result · 2012-08-09Clinical Trial Update: Reduced Intensity Preparative Regimen Followed by Stem Cell Transplant (FAB) [Phase 1, Phase 2]
Clinical trial update on a reduced-intensity preparative regimen followed by stem cell transplantation (FAB) in several hematologic malignan…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Allo Transplantation With Mylotarg, Fludarabine and Melphalan for AML, CML and MDS [Phase 1, Phase 2]
An allogeneic transplant regimen using Mylotarg with fludarabine and melphalan was studied for acute myeloid leukemia, chronic myeloid leuke…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Zarnestra and Gleevec in Chronic Phase Chronic Myelogenous Leukemia [Phase 1]
Phase 1 trial update of Zarnestra (tipifarnib) in combination with Gleevec (imatinib) for chronic-phase chronic myeloid leukemia. The trial …
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating peripheral stem cell transplantation with filgrastim in patients with acute or chronic myeloid leukemia; the study …
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CLINICAL_TRIALS trial_result · 2012-07-30Clinical Trial Update: Decitabine and Peripheral Stem Cell Transplantation in Treating Patients Who Have Relapsed Following Bone Marrow Transplantation for Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating decitabine with peripheral stem cell transplantation in patients relapsed after bone marrow transplantat…
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CLINICAL_TRIALS research · 2012-07-30Clinical Trial Update: Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
Phase 2 clinical trial update evaluating chemotherapy and biological therapy for chronic phase chronic myeloid leukemia has completed.
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant [Phase 1]
Phase 1 safety study of interleukin-7 in recipients of a hematopoietic stem cell transplant (peripheral blood) has completed.
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CLINICAL_TRIALS approval · 2012-07-18Clinical Trial Update: Nilotinib in Adult Patients With Imatinib-resistant or Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase
Marketing approval of nilotinib for adult chronic myeloid leukemia in imatinib-resistant or intolerant patients across blast crisis, acceler…
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CLINICAL_TRIALS trial_result · 2012-07-17Clinical Trial Update: Dasatinib and Vorinostat in Treating Patients With Accelerated Phase or Blastic Phase Chronic Myelogenous Leukemia or Acute Lymphoblastic Leukemia [Phase 1]
Phase 1 study evaluating the combination of dasatinib and vorinostat in patients with accelerated or blast phase chronic myeloid leukemia or…
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CLINICAL_TRIALS trial_result · 2012-07-11Clinical Trial Update: Imatinib Mesylate Plus Cytarabine in Treating Patients With Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 clinical trial evaluating the combination of imatinib mesylate and cytarabine in patients with chronic myeloid leukemia was termin…
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CLINICAL_TRIALS trial_result · 2012-07-10Clinical Trial Update: Imatinib Mesylate or Dasatinib in Treating Patients With Previously Untreated Chronic Phase Chronic Myelogenous Leukemia [Phase 2]
A Phase 2 trial comparing imatinib mesylate and dasatinib in previously untreated chronic phase chronic myeloid leukemia, with results poste…
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CLINICAL_TRIALS trial_result · 2012-06-25Clinical Trial Update: Discontinuation of Dasatinib in Patients With Chronic Myeloid Leukemia-CP Who Have Maintained Complete Molecular Remission for Two Years; Dasatinib Stop Trial [Phase 2]
A Phase 2 trial investigates discontinuing dasatinib in patients with chronic myeloid leukemia in chronic phase who have maintained complete…