Chronic Myeloid Leukemia
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Sign up freeTop drugs studied for this disease
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FDA approval · 2015-10-08FDA Approved: BOSULIF — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
The FDA approved a supplemental application for Bosulif (bosutinib) submitted by Pfizer Laboratories Div Pfizer Inc. This approval updates a…
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CLINICAL_TRIALS trial_result · 2015-09-25Clinical Trial Update: Hematopoietic Stem Cell Transplantation (HSCT) Using CD34 Selected Mismatched Related Donor and One Umbilical Cord Unit [Phase 2]
Phase 2 clinical trial evaluating hematopoietic stem cell transplantation using a CD34-selected mismatched related donor plus one umbilical …
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FDA approval · 2015-09-22FDA Approved: BOSULIF — Supplemental Application (Pfizer Laboratories Div Pfizer Inc)
FDA approved a supplemental application for BOSULIF (bosutinib) from Pfizer Laboratories Div Pfizer Inc.
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CLINICAL_TRIALS trial_result · 2015-09-17Clinical Trial Update: Dasatinib in Patients With Chronic Myeloid Leukemia in Chronic Phase [Phase 2]
A Phase 2 clinical trial evaluating dasatinib in patients with chronic myeloid leukemia in chronic phase; the trial status is currently unkn…
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CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: A Study of Complete Molecular Response for Chronic Myeloid Leukemia in Chronic Phase Patients, Treated With Dasatinib [Phase 2]
A Phase 2 trial evaluating dasatinib in chronic myeloid leukemia in chronic phase reports results related to complete molecular response.
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CLINICAL_TRIALS trial_result · 2015-09-15Clinical Trial Update: A Study of Dasatinib in Patients With Imatinib Resistant or Intolerant Chronic Myeloid Leukemia [Phase 2]
A Phase 2 trial evaluating dasatinib in patients with imatinib-resistant or -intolerant chronic myeloid leukemia has completed. The update s…
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CLINICAL_TRIALS trial_result · 2015-09-09Clinical Trial Update: Pulmonary Vasculopathy Under Second-line Therapy of Chronic Myeloid Leukemia
This is a completed clinical trial conducted by the Medical University of Graz investigating pulmonary vasculopathy in patients with chronic…
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CLINICAL_TRIALS withdrawal · 2015-08-31Clinical Trial Update: A Phase I Trial of Alloreactive Cell Infusion Following Transplantation of Haplotype Cells in Patients With Myeloid Malignancies [Phase 1]
A Phase I study of an alloreactive cell infusion following transplantation of haplotype cells in patients with myeloid malignancies has been…
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CLINICAL_TRIALS trial_result · 2015-08-25Clinical Trial Update: MK0457 in Patients With Leukemia (0457-003) [Phase 1]
Phase 1 trial update for MK-0457 (VX-680) in leukemia patients has completed; the study included chronic myeloid leukemia in blast crisis, a…
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CLINICAL_TRIALS withdrawal · 2015-08-25Clinical Trial Update: Autologous Stem Cell Transplants for Chronic Myelogenous Leukemia [Phase 2]
Phase 2 trial evaluating autologous stem cell transplantation for chronic myeloid leukemia has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-08-21Clinical Trial Update: Study of XL228 in Subjects With Chronic Myeloid Leukemia or Philadelphia-Chromosome-Positive Acute Lymphocytic Leukemia [Phase 1]
Clinical trial update for XL228 in chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia; the Phase 1 s…
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CLINICAL_TRIALS research · 2015-07-30Clinical Trial Update: A Phase II Study to Evaluate the Efficacy and the Safety of Flumatinib in CML-AP or CML-BP Patients [Phase 2]
A Phase II clinical trial assessing the efficacy and safety of Flumatinib in patients with chronic myeloid leukemia in accelerated or blast …
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CLINICAL_TRIALS trial_result · 2015-07-10Clinical Trial Update: Efficacy and Safety Study of StemEx®, to Treat Subjects With High Risk Hematologic Malignancies, Following Myeloablative Therapy [Phase 2, Phase 3]
This update summarizes a Phase 2/Phase 3 study of StemEx for high-risk hematologic malignancies after myeloablative therapy, focusing on eff…
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CLINICAL_TRIALS trial_result · 2015-07-07Clinical Trial Update: Healthcare Costs Among Patients With CML Receiving Dasatinib or Nilotinib in a Commercial and Medicare Population
This completed clinical trial analyzes healthcare costs among patients with Chronic Myeloid Leukemia treated with dasatinib or nilotinib in …
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CLINICAL_TRIALS trial_result · 2015-06-22Clinical Trial Update: Study Evaluating the Tolerance and Biologic Activity of Oral Ciclopirox Olamine in Patients With Relapsed or Refractory Hematologic Malignancy [Phase 1]
This Phase 1 clinical trial update reports the tolerance and biologic activity of oral ciclopirox olamine in patients with relapsed or refra…
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: Study of Farnesyl Protein Transferase Inhibitor (FPTI) in Patients With Leukemia (Study P00701) [Phase 1, Phase 2]
Phase 1/2 trial of a Farnesyl Protein Transferase Inhibitor in leukemia and myelodysplastic syndromes has completed, sponsored by Merck Shar…
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CLINICAL_TRIALS trial_result · 2015-06-11Clinical Trial Update: Abdominal CT to Predict the Risk of Acute Graft-versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation [EARLY_Phase 1]
An early-phase study update reporting completion of a trial using abdominal CT to predict acute graft-versus-host disease risk after allogen…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: Phase I Study of OPB-51602 in Patients With Hematologic Malignancies [Phase 1]
Phase I trial results are reported for OPB-51602 in patients with hematologic malignancies including multiple myeloma, non-Hodgkin lymphoma,…
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CLINICAL_TRIALS trial_result · 2015-05-27Clinical Trial Update: Safety of Zileuton (Zyflo) in Combination With Imatinib Mesylate (Gleevec) in CML. [Phase 1]
Phase 1 trial assessing the safety of combining zileuton (Zyflo) with imatinib mesylate (Gleevec) in chronic myeloid leukemia; the study was…
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CLINICAL_TRIALS trial_result · 2015-05-19Clinical Trial Update: Bioequivalence Study of Mesylate Imatinib Capsule in Chronic Myeloid Leukemia Body [Phase 1]
Phase 1 bioequivalence study of imatinib mesylate capsule in chronic myeloid leukemia; results were posted on 2015-05-19.
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CLINICAL_TRIALS withdrawal · 2015-05-15Clinical Trial Update: RAD001 in Patients With Chronic Phase Chronic Myeloid Leukemia w/ Molecular Disease. [Phase 1, Phase 2]
A Phase 1/2 study of everolimus (RAD001) in patients with chronic phase chronic myeloid leukemia with molecular disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-05-07Clinical Trial Update: Study of Hypoxia-Activated Prodrug TH-302 to Treat Advanced Leukemias [Phase 1]
Phase 1 study of TH-302 (evofosfamide), a hypoxia-activated prodrug, in patients with advanced leukemias has been completed, with evaluation…
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CLINICAL_TRIALS trial_result · 2015-05-05Clinical Trial Update: Determining the Maximum Tolerated Dose of Low Dose Interferon-alpha in Conjunction With Nilotinib in Pretreated Philadelphia Chromosome Positive (Ph+) Chronic Myeloid Leukemia Patients in Chronic Phase (CML-CP) [Phase 1]
Phase 1 trial completed to determine the maximum tolerated dose of low-dose interferon-alpha in combination with nilotinib for patients with…
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CLINICAL_TRIALS research · 2015-04-30Clinical Trial Update: Development of Immunological Assays for the Evaluation of Tumor Antigen Specific Immunity
A completed clinical trial update on developing immunological assays to evaluate tumor antigen-specific immunity. The study includes ovarian…
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FDA approval · 2015-04-23FDA Approved: ICLUSIG — Supplemental Application (Takeda Pharmaceuticals America, Inc.)
FDA approved a supplemental application for ICLUSIG (ponatinib hydrochloride) submitted by Takeda Pharmaceuticals America, Inc., under NDA 2…