Chronic Lymphocytic Leukemia
📧 Sign up to get email alerts when something new happens for Chronic Lymphocytic Leukemia.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2014-10-06Clinical Trial Update: Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma [Phase 1, Phase 2]
This ClinicalTrials.gov update reports a terminated phase 1/2 trial evaluating fenretinide with rituximab for B-cell non-Hodgkin lymphomas; …
-
CLINICAL_TRIALS trial_result · 2014-09-11Clinical Trial Update: Investigation of the Cylex® ImmuKnow® Assay
A completed clinical trial investigating the Cylex ImmuKnow immune function assay across several hematologic diseases.
-
CLINICAL_TRIALS trial_result · 2014-09-10Clinical Trial Update: CHAIROS Study A Study of MabThera/Rituxan (Rituximab) Maintenance Therapy in Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Naive to Chemotherapy [Phase 2]
Phase 2 trial update describing results for Rituximab maintenance therapy in patients with chronic lymphocytic leukemia naive to chemotherap…
-
CLINICAL_TRIALS trial_result · 2014-09-08Clinical Trial Update: Phase 2 Fludarabine, Cytoxan and FCCAM <Alemtuzumab> in Untreated B-Cell Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial of fludarabine, cyclophosphamide and alemtuzumab in untreated B-cell chronic lymphocytic leukemia has completed with results p…
-
FDA approval · 2014-09-05FDA Approved: CAMPATH — Supplemental Application (Genzyme Corporation)
The FDA approved a supplemental application for CAMPATH (alemtuzumab) submitted by Genzyme Corporation.
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2014-09-03Clinical Trial Update: Clinical Study of Relapsed/Refractory Chronic Lymphocytic Leukemia (CLL) [Phase 1]
A Phase 1 clinical study in relapsed/refractory chronic lymphocytic leukemia sponsored by Piramal Enterprises is currently suspended.
-
CLINICAL_TRIALS trial_result · 2014-09-01Clinical Trial Update: Lenalidomide in Comb w/Rituximab for Pts w/CD5+/CD20+ Hem Malignancies Who Relapse/Progress After Rituximab [Phase 2]
A phase 2 trial evaluating lenalidomide plus rituximab in patients with CD5+/CD20+ hematologic malignancies who relapse after rituximab, inc…
-
CLINICAL_TRIALS trial_result · 2014-08-18Clinical Trial Update: Lenalidomide Following Fludarabine/Rituximab (FR) in Untreated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating lenalidomide after fludarabine/rituximab in untreated chronic lymphocytic leukemia has completed with results poste…
-
CLINICAL_TRIALS trial_result · 2014-08-13Clinical Trial Update: A Phase I Trial Using Cyclophosphamide, Rituximab and Revlimid (CR2) for the Treatment of Relapsed/Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL) and Small Lymphocytic Lymphoma (SLL) [Phase 1]
This document reports the termination of a Phase I trial evaluating cyclophosphamide, rituximab, and lenalidomide (CR2) for relapsed/refract…
-
CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: Rituximab and GM-CSF in Treating Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating rituximab in combination with GM-CSF for chronic lymphocytic leukemia; the study is terminated.
-
CLINICAL_TRIALS trial_result · 2014-07-24Clinical Trial Update: Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL) [Phase 1]
Phase 1 safety and tolerability study evaluating the BTK inhibitor PCI-32765 (ibrutinib) in combination with FCR or BR regimens in chronic l…
-
FDA approval · 2014-07-23FDA Approved: ZYDELIG — Original Application (Gilead Sciences, Inc.)
FDA approved ZYDELIG (idelalisib) from Gilead Sciences as a new molecular therapy for adults with relapsed or refractory follicular lymphoma…
-
CLINICAL_TRIALS trial_result · 2014-07-08Clinical Trial Update: Phase IV Observational Study in Chronic Lymphocytic Leukemia
GlaxoSmithKline conducted a Phase IV observational study in chronic lymphocytic leukemia. The study status is COMPLETED.
-
CLINICAL_TRIALS trial_result · 2014-07-04Clinical Trial Update: Open-label Extension Study of Navitoclax in Subjects With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
This document provides an update on an open-label extension phase 2 trial of navitoclax in patients with chronic lymphocytic leukemia, notin…
-
CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: A Proof of Concept Study of the Safety, Tolerability, and Efficacy of Avastin (Bevacizumab) in Patients With Chemo-naive Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 proof-of-concept trial evaluating Avastin (bevacizumab) for safety, tolerability, and efficacy in chemo-naive chronic lymphocytic le…
-
CLINICAL_TRIALS trial_result · 2014-06-26Clinical Trial Update: A Study of Motexafin Gadolinium for the Treatment of Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial of motexafin gadolinium for chronic lymphocytic leukemia was terminated.
-
CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: Pentostatin, Alemtuzumab, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating a combination of pentostatin, alemtuzumab, and rituximab in relapsed or refractory chronic lymphocytic leukemia or …
-
CLINICAL_TRIALS trial_result · 2014-06-20Clinical Trial Update: Study of Low-Intensity Conditioning for Allogeneic Stem Cell Transplant [Phase 2]
A Phase 2 trial evaluating low-intensity conditioning for allogeneic stem cell transplantation in multiple myeloma, chronic lymphocytic leuk…
-
CLINICAL_TRIALS trial_result · 2014-06-19Clinical Trial Update: AZD6738 First Time in Patient Multiple Ascending Dose Study [Phase 1]
AZD6738 (berzosertib) was studied in a first-in-patient, multiple ascending-dose Phase 1 trial in relapsed/refractory hematologic cancers in…
-
CLINICAL_TRIALS research · 2014-06-05Clinical Trial Update: Observational Study of Low Dose FCR in Elderly/Comorbid CLL/SLL: The Q-lite Project
Observational study (the Q-lite Project) evaluating low-dose fludarabine-cyclophosphamide-rituximab (FCR) in elderly or comorbid patients wi…
-
CLINICAL_TRIALS trial_result · 2014-05-26Clinical Trial Update: High-dose HMG-CoA Inhibitor Simvastatin Relapsed CLL [Phase 1]
This report covers a Phase 1 trial evaluating high-dose simvastatin, an HMG-CoA reductase inhibitor, in relapsed chronic lymphocytic leukemi…
-
EMA approval · 2014-05-23European Medicines Agency recommends approval of Gazyvaro for chronic lymphocytic leukaemia
The European Medicines Agency recommends approval of Gazyvaro for chronic lymphocytic leukemia, supporting its use for this indication.
-
CLINICAL_TRIALS other · 2014-05-23Clinical Trial Update: Study of Motexafin Gadolinium (MGd) in Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
A phase 2 trial of Motexafin Gadolinium in chronic lymphocytic leukemia or small lymphocytic lymphoma has been terminated.
-
CLINICAL_TRIALS trial_result · 2014-05-22Clinical Trial Update: Study of Noscapine for Patients With Low Grade Non Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia Refractory to Chemotherapy [Phase 1, Phase 2]
A Phase 1/2 clinical trial of noscapine in patients with low-grade non-Hodgkin lymphoma or chronic lymphocytic leukemia refractory to chemot…
-
CLINICAL_TRIALS trial_result · 2014-05-12Clinical Trial Update: A Phase I/II Study of GX15-070MS in Untreated CLL [Phase 1]
A Phase I/II trial of GX15-070MS (obatoclax mesylate) in untreated chronic lymphocytic leukemia has completed the Phase 1 portion reported b…