Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-03-09Clinical Trial Update: Haploid Allogeneic Transplant Using the CliniMACS System [Phase 2]
A Phase 2 clinical trial evaluating haploid allogeneic transplantation using the CliniMACS System was terminated, with results posted in 201…
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: First in Human Study to Determine the Safety, Tolerability and Preliminary Efficacy of an Anti-CXCR4 Antibody in Subjects With Acute Myelogenous Leukemia and Selected B-cell Cancers [Phase 1]
First-in-human Phase 1 trial assessing safety, tolerability, and preliminary efficacy of an anti-CXCR4 antibody in acute myeloid leukemia an…
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CLINICAL_TRIALS withdrawal · 2015-03-06Clinical Trial Update: Fludarabine Phosphate, Rituximab, and Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Relapsed or Not Responded To Treatment [Phase 2]
A Phase 2 trial of fludarabine phosphate, rituximab, and bevacizumab in relapsed or refractory B-cell chronic lymphocytic leukemia has been …
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CLINICAL_TRIALS withdrawal · 2015-03-06Clinical Trial Update: S0902 Bendamustine and Rituximab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Not Responded to Previous Treatment [Phase 2]
A Phase 2 trial of bendamustine plus rituximab for B-cell chronic lymphocytic leukemia that has not responded to prior treatment has been wi…
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CLINICAL_TRIALS withdrawal · 2015-03-06Clinical Trial Update: Lenalidomide With or Without Rituximab in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Who Have Undergone Autologous or Syngeneic Stem Cell Transplant [Phase 2]
Phase 2 trial of lenalidomide with or without rituximab in patients with chronic lymphocytic leukemia or small lymphocytic lymphoma after au…
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CLINICAL_TRIALS research · 2015-03-04Clinical Trial Update: Heavy Light Chain in Chronic Lymphocytic Leukemia
This entry provides a clinical trial update on heavy light chain research in chronic lymphocytic leukemia, sponsored by Bnai Zion Medical Ce…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Feasibility Study of a 60 Minute Rapid Infusion Rituximab Protocol in Patients With B-cell Malignancies [Phase 2]
A Phase 2 feasibility study evaluating a 60-minute rapid infusion rituximab protocol in patients with indolent or intermediate-grade B-cell …
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CLINICAL_TRIALS trial_result · 2015-02-16Clinical Trial Update: A Study of MabThera (Rituximab) Plus Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia. [Phase 2]
Phase 2 trial evaluating MabThera (rituximab) plus chlorambucil in patients with previously untreated chronic lymphocytic leukemia; the stud…
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CLINICAL_TRIALS trial_result · 2015-02-12Clinical Trial Update: Reduced Intensity Total Body Irradiation + Thymoglobulin Followed by Allogeneic PBSCT [Phase 2]
Phase 2 clinical trial evaluating reduced intensity total body irradiation plus Thymoglobulin followed by allogeneic peripheral blood stem c…
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CLINICAL_TRIALS trial_result · 2015-02-11Clinical Trial Update: Pilot Study of Unrelated Cord Blood Transplantation [Phase 2]
Phase 2 pilot trial of unrelated cord blood transplantation sponsored by King's College Hospital NHS Trust has been terminated.
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CLINICAL_TRIALS trial_result · 2015-02-10Clinical Trial Update: A Study of Dinaciclib in Combination With Rituximab in Participants With Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma (P07974) [Phase 1]
This Phase 1 trial evaluated the combination of dinaciclib and rituximab in patients with chronic lymphocytic leukemia and small lymphocytic…
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CLINICAL_TRIALS trial_result · 2015-02-03Clinical Trial Update: Ofatumumab Added to Dexamethasone in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial evaluated adding ofatumumab to dexamethasone in patients with relapsed or refractory chronic lymphocytic leukemia, and the s…
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CLINICAL_TRIALS trial_result · 2015-01-27Clinical Trial Update: Rituximab, Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Low-Grade Follicular Lymphoma, Waldenstrom Macroglobulinemia, or Mantle Cell Lymphoma [Phase 2]
Phase 2 clinical trial evaluating rituximab, cyclophosphamide, bortezomib, and dexamethasone in relapsed/refractory low-grade follicular lym…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Stem Cell Transplantation for Patients With Cancers of the Blood [Phase 2]
Phase 2 trial update reporting results from stem cell transplantation for patients with blood cancers, including chronic myeloid leukemia, c…
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CLINICAL_TRIALS trial_result · 2015-01-06Clinical Trial Update: Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants [Phase 2]
Phase 2 clinical trial update on methods to enhance safety and effectiveness of stem cell transplants.
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CLINICAL_TRIALS trial_result · 2014-12-23Clinical Trial Update: A Phase I Study of GNKG168 in Patient With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (B-CLL) [Phase 1]
This clinical trial update reports that GNKG168 in relapsed or refractory B-cell chronic lymphocytic leukemia (Phase I) has been terminated.
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CLINICAL_TRIALS research · 2014-12-18Clinical Trial Update: A Safety Study in Patients With Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
This document notes a completed Phase 1/Phase 2 safety study in patients with chronic lymphocytic leukemia sponsored by Seagen.
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CLINICAL_TRIALS trial_result · 2014-11-24Clinical Trial Update: Ofatumumab vs Physician's Choice in Subjects With Bulky Fludarabine-Refractory Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial comparing Ofatumumab to physician's choice in bulky, fludarabine-refractory chronic lymphocytic leukemia has completed with re…
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CLINICAL_TRIALS trial_result · 2014-11-10Clinical Trial Update: A Two-Step Approach to Bone Marrow Transplant Using Cells From Two Partially-Matched Relatives [Phase 2]
Phase 2 clinical trial investigating a two-step bone marrow transplant using cells from two partially matched relatives was terminated; resu…
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CLINICAL_TRIALS other · 2014-10-28Clinical Trial Update: Expanded Access for Idelalisib in Combination With Rituximab in Chronic Lymphocytic Leukemia
Expanded-access program launched for idelalisib in combination with rituximab to treat chronic lymphocytic leukemia.
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CLINICAL_TRIALS trial_result · 2014-10-23Clinical Trial Update: Maintenance Therapy: Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial tested lenalidomide as maintenance therapy after Bendamustine and Rituximab induction in chronic lymphocytic leukemia; the s…
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CLINICAL_TRIALS research · 2014-10-17Clinical Trial Update: Tissue Collection for Biomarkers Determining Resistance to Ibrutinib
Trial update on tissue collection for biomarkers to determine resistance to ibrutinib in mantle cell lymphoma and chronic lymphocytic leukem…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: Bendamustine Hydrochloride (HCl) in Indolent Non-Hodgkin's Lymphoma That Has Progressed During or Following Treatment With a Rituximab Regimen or Previously Untreated Chronic Lymphocytic Leukemia [Phase 3]
A Phase 3 trial of bendamustine hydrochloride for indolent non-Hodgkin lymphoma and chronic lymphocytic leukemia completed, with results pos…
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CLINICAL_TRIALS trial_result · 2014-10-16Clinical Trial Update: A Randomized, Double-Blind, Placebo-Controlled Study of Idelalisib in Combination With Rituximab for Previously Treated Chronic Lymphocytic Leukemia (CLL) [Phase 3]
A Phase 3 randomized, double-blind trial evaluating idelalisib plus rituximab vs control in previously treated chronic lymphocytic leukemia …
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CLINICAL_TRIALS trial_result · 2014-10-10Clinical Trial Update: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 2) [Phase 3]
Phase 3 trial of obinutuzumab with chlorambucil in previously untreated chronic lymphocytic leukemia completed, with results posted in 2014.