Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-05-09Clinical Trial Update: Pentostatin, Cyclophosphamide, and Rituximab With or Without Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial assessing pentostatin, cyclophosphamide, and rituximab with or without bevacizumab in patients with chronic lymphocytic leukem…
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CLINICAL_TRIALS trial_result · 2014-05-01Clinical Trial Update: Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia [Phase 1]
Phase 1 trial evaluating obatoclax mesylate in combination with vincristine, doxorubicin, and dexrazoxane in pediatric patients with relapse…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: A Study Comparing Obinutuzumab (RO5072759; GA101) 1000 Milligram (mg) Versus 2000 mg in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (GAGE) [Phase 2]
Phase 2 trial comparing two dosing regimens of obinutuzumab in previously untreated chronic lymphocytic leukemia; the study (GAGE) is comple…
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CLINICAL_TRIALS trial_result · 2014-04-24Clinical Trial Update: Bryostatin 1 Plus Cladribine in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluated Bryostatin-1 in combination with Cladribine for relapsed chronic lymphocytic leukemia. The study has completed.
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CLINICAL_TRIALS trial_result · 2014-04-21Clinical Trial Update: Safety and Tolerability of XmAb®5574 in Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 study evaluating safety and tolerability of XmAb5574 in patients with chronic lymphocytic leukemia and small lymphocytic lymphoma …
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CLINICAL_TRIALS trial_result · 2014-04-10Clinical Trial Update: Sorafenib in Treating Patients With Relapsed Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 trial evaluating sorafenib for relapsed chronic lymphocytic leukemia was terminated; results were posted in 2014.
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CLINICAL_TRIALS research · 2014-04-04Clinical Trial Update: Study Assessing Safety and Efficiency of the Lenalidomide and Dexamethasone Combination in Patients With Chronic Lymphatic Leukemia (CLL) Relapsing or Resistant to Treatment [Phase 1, Phase 2]
This is a completed Phase 1/2 clinical trial evaluating the safety and efficacy of the lenalidomide and dexamethasone combination in relapse…
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CLINICAL_TRIALS trial_result · 2014-04-01Clinical Trial Update: CLL11: A Study of Obinutuzumab (RO5072759 [GA101]) With Chlorambucil in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1a) [Phase 3]
Phase 3 trial in previously untreated chronic lymphocytic leukemia evaluating obinutuzumab with chlorambucil completed.
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: Safety of PCI-32765 in Chronic Lymphocytic Leukemia [Phase 1, Phase 2]
Clinical trial update reporting safety data for the BTK inhibitor ibrutinib (PCI-32765) in patients with chronic lymphocytic leukemia and sm…
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CLINICAL_TRIALS trial_result · 2014-03-31Clinical Trial Update: T-Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Hematologic Malignancies [Phase 2]
Phase 2 clinical trial evaluating T-cell depleted allogeneic stem cell transplantation for hematologic malignancies; study is completed with…
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FDA approval · 2014-03-27FDA Approved: TREANDA — Supplemental Application (Cephalon, LLC)
FDA approved a supplemental application for TREANDA (bendamustine hydrochloride) submitted by Cephalon, LLC.
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CLINICAL_TRIALS trial_result · 2014-03-26Clinical Trial Update: Ofatumumab + Chlorambucil vs Chlorambucil Monotherapy in Previously Untreated Patients With Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial evaluating ofatumumab plus chlorambucil versus chlorambucil alone in previously untreated chronic lymphocytic leukemia; trial …
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CLINICAL_TRIALS trial_result · 2014-02-27Clinical Trial Update: Lenalidomide as Chemoprevention in Treating Patients With High-Risk, Early-Stage B-Cell Chronic Lymphocytic Leukemia [NA]
A terminated clinical trial evaluating lenalidomide as chemoprevention in high-risk, early-stage B-cell chronic lymphocytic leukemia has pos…
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CLINICAL_TRIALS trial_result · 2014-02-24Clinical Trial Update: Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma [Phase 1]
Phase 1 study of oxaliplatin, ifosfamide, and etoposide in young patients with recurrent or refractory solid tumors or lymphomas; the trial …
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CLINICAL_TRIALS trial_result · 2014-02-19Clinical Trial Update: The Duration of Humoral Immunity and the Memory Cell Function After Vaccination With 7-valent Pneumococcal Conjugate Vaccine in CLL [Phase 4]
Phase 4 study assessing how durable the humoral immune response and memory cell function are after vaccination with the 7-valent pneumococca…
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CLINICAL_TRIALS trial_result · 2014-02-11Clinical Trial Update: CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial evaluating CCI-779 (temsirolimus) in patients with recurrent or refractory B-cell non-Hodgkin lymphoma or chronic l…
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CLINICAL_TRIALS trial_result · 2014-02-10Clinical Trial Update: Sunitinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 2]
Phase 2 trial evaluating sunitinib in relapsed or refractory chronic lymphocytic leukemia and small lymphocytic lymphoma has completed with …
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CLINICAL_TRIALS trial_result · 2014-02-07Clinical Trial Update: A Phase 1 Study of Novel GS-9973 Tablet Formulations to Evaluate the Effect of Acid Reducing Agents, Relative Bioavailability, and Food Effect on GS-9973 Pharmacokinetics [Phase 1]
Phase 1 study evaluating GS-9973 tablet formulations to assess the impact of acid-reducing agents, food, and relative bioavailability on pha…
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CLINICAL_TRIALS trial_result · 2014-02-04Clinical Trial Update: A Trial of GS-9219 in Chronic Lymphocytic Leukemia (CLL), Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM) [Phase 1, Phase 2]
Clinical trial GS-9219 in chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma (Phase 1/2) has been terminated.
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CLINICAL_TRIALS trial_result · 2014-02-03Clinical Trial Update: Treatment of B-Chronic Lymphocytic Leukemia (B-CLL) With Autologous CD40 Ligand and IL-2-Expressing Tumor Cells [Phase 1]
This completed Phase 1 study evaluated an autologous CD40 ligand approach combined with IL-2-expressing tumor cells for chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2014-01-28Clinical Trial Update: CLL11: A Study of Rituximab With Chlorambucil or Chlorambucil Alone in Patients With Previously Untreated Chronic Lymphocytic Leukemia (Stage 1b) [Phase 3]
Phase 3 trial evaluating rituximab with chlorambucil versus chlorambucil alone in previously untreated chronic lymphocytic leukemia; results…
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CLINICAL_TRIALS trial_result · 2014-01-13Clinical Trial Update: Lenalidomide in Previously Treated Patients With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 2]
This Phase 2 clinical trial update evaluates lenalidomide in previously treated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma.…
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CLINICAL_TRIALS withdrawal · 2014-01-13Clinical Trial Update: Azadirachta Indica in Treating Patients With Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 trial evaluating Azadirachta Indica for chronic lymphocytic leukemia has been withdrawn.
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CLINICAL_TRIALS research · 2014-01-10Clinical Trial Update: Valproic Acid in Treating Patients With Previously Treated Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Chronic Lymphocytic Leukemia [Phase 2]
A Phase 2 clinical trial update evaluating valproic acid in patients with previously treated non-Hodgkin lymphoma, Hodgkin lymphoma, or chro…
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CLINICAL_TRIALS trial_result · 2014-01-09Clinical Trial Update: Compassionate Use of Campath-1H in Treating Patients With Refractory Prolymphocytic Leukemia or Chronic Lymphocytic Leukemia [NA]
This clinical trial update reports compassionate-use treatment with Campath-1H (alemtuzumab) for patients with refractory prolymphocytic leu…