Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2016-06-22Clinical Trial Update: Pilot Study of Autologous T Lymphocytes With ADCC in Patients With CD20-Positive B-Cell Malignancies [Phase 1, Phase 2]
Phase 1/Phase 2 pilot study evaluating autologous T lymphocytes with antibody-dependent cellular cytotoxicity in CD20-positive B-cell malign…
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CLINICAL_TRIALS trial_result · 2016-06-21Clinical Trial Update: Multicentre Registry of Treatments and Outcomes in Patients With Chronic Lymphocytic Leukaemia (CLL) Or Indolent Non Hodgkin's Lymphoma (iNHL)
A multicenter registry examining treatments and outcomes for patients with chronic lymphocytic leukemia and indolent non-Hodgkin lymphoma ha…
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
A Stanford-sponsored clinical trial evaluating allogeneic transplantation for acute and chronic leukemias has been terminated.
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CLINICAL_TRIALS research · 2016-06-09Clinical Trial Update: CD22 Targeting CAR-T Therapy Against B Cell Hematological Malignancies [Phase 1, Phase 2]
This entry reports a phase 1/2 clinical trial of a CD22-targeted CAR-T therapy for recurrent or refractory B-cell malignancies; the status i…
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CLINICAL_TRIALS trial_result · 2016-05-27Clinical Trial Update: Dose Escalation Study of Revlimid With Fludarabine-Rituximab for CLL/SLL [Phase 1]
A Phase 1 dose-escalation study of lenalidomide (Revlimid) with fludarabine-rituximab in patients with chronic lymphocytic leukemia and smal…
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CLINICAL_TRIALS trial_result · 2016-05-26Clinical Trial Update: Fludarabine/Rituximab Combined With Escalating Doses of Lenalidomide in Untreated CLL [Phase 1, Phase 2]
This update reports results from a Phase 1/2 trial evaluating escalating doses of lenalidomide added to fludarabine and rituximab in previou…
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CLINICAL_TRIALS trial_result · 2016-05-13Clinical Trial Update: Weekly Subcutaneous Alemtuzumab and Rituximab for Relapsed CLL [Phase 1]
Phase 1 trial evaluating weekly subcutaneous alemtuzumab and rituximab for relapsed chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS other · 2016-05-13Clinical Trial Update: Treatment of Chronic Lymphocytic Leukemia
This clinical trial update concerns the treatment of chronic lymphocytic leukemia (B-cell) sponsored by Peking University People's Hospital;…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Study of Lenalidomide in Previously Untreated, Symptomatic Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase 2 study of lenalidomide in previously untreated, symptomatic chronic lymphocytic leukemia was terminated. Results were posted in 201…
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CLINICAL_TRIALS trial_result · 2016-05-12Clinical Trial Update: Pentostatin, Cyclophosphamide, Rituximab, and Mitoxantrone in Treating Patients With Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Cancer [Phase 1, Phase 2]
Phase 1/2 study evaluating a four-drug regimen (pentostatin, cyclophosphamide, rituximab, mitoxantrone) in patients with chronic lymphocytic…
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CLINICAL_TRIALS trial_result · 2016-05-09Clinical Trial Update: Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL) [Phase 1]
Phase 1 study of carfilzomib in patients with chronic lymphocytic leukemia, small lymphocytic lymphoma, or prolymphocytic leukemia has compl…
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Open-label Phase 3 BTK Inhibitor Ibrutinib vs Chlorambucil Patients 65 Years or Older With Treatment-naive CLL or SLL [Phase 3]
Phase 3 open-label trial comparing ibrutinib to chlorambucil in patients 65 years or older with treatment-naive chronic lymphocytic leukemia…
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CLINICAL_TRIALS trial_result · 2016-05-04Clinical Trial Update: Fludarabine, Rituximab, and Lenalidomide in Minimally Treated/Untreated Patients With Chronic Lymphocytic Leukemia (CLL) [Phase 1, Phase 2]
This document reports results from a Phase 1/2 clinical trial evaluating fludarabine, rituximab, and lenalidomide in minimally treated or un…
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CLINICAL_TRIALS trial_result · 2016-05-02Clinical Trial Update: A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 study evaluating Rituximab (MabThera) in chronic lymphocytic leukemia has completed and results have been posted.
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CLINICAL_TRIALS research · 2016-04-29Clinical Trial Update: Combination of Ibrutinib and As2O3 in the Treatment of CLL [Phase 3]
Phase 3 trial evaluating the combination of ibrutinib and arsenic trioxide for chronic lymphocytic leukemia; the status is currently unknown…
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CLINICAL_TRIALS trial_result · 2016-04-25Clinical Trial Update: A Study of Obinutuzumab in Chinese Participants With CD20+ Malignant Disease [Phase 1]
Phase 1 trial results for obinutuzumab in Chinese participants with CD20+ malignant disease. Diseases studied include chronic lymphocytic le…
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CLINICAL_TRIALS research · 2016-04-20Clinical Trial Update: Thiotepa-based Conditioning for Allogeneic Stem-cell Transplantation (SCT) in Lymphoid Malignancies [Phase 2]
Phase 2 clinical trial investigating thiotepa-based conditioning for allogeneic stem-cell transplantation in lymphoid malignancies, includin…
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CLINICAL_TRIALS trial_result · 2016-04-19Clinical Trial Update: Safety Study of CC-292 and Rituximab in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma [Phase 1]
A completed Phase 1 safety study evaluating CC-292 in combination with Rituximab in patients with chronic lymphocytic leukemia and/or small …
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FDA approval · 2016-04-11FDA Approved: VENCLEXTA — Original Application (AbbVie Inc.)
FDA approved the original application for VENCLEXTA (venetoclax) by AbbVie. The approval covers the treatment of chronic lymphocytic leukemi…
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CLINICAL_TRIALS trial_result · 2016-04-06Clinical Trial Update: A Study of MabThera (Rituximab) Plus Chlorambucil in Participants With Chronic Lymphocytic Leukemia. [Phase 2]
Phase 2 study evaluating Rituximab (MabThera) plus chlorambucil in participants with chronic lymphocytic leukemia; the trial completed and r…
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CLINICAL_TRIALS trial_result · 2016-04-01Clinical Trial Update: Study Combining SAR245409 With Rituximab or Bendamustine Plus Rituximab in Patients With Indolent Lymphoma, Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia [Phase 1]
A Phase 1 study evaluating SAR245409 in combination with rituximab or bendamustine plus rituximab in patients with indolent non-Hodgkin lymp…
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CLINICAL_TRIALS trial_result · 2016-03-29Clinical Trial Update: Efficacy and Safety Study of SyB L-0501 for Patients With Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating the efficacy and safety of SyB L-0501 in patients with Chronic Lymphocytic Leukemia has completed and posted result…
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FDA approval · 2016-03-21FDA Approved: IMBRUVICA — Supplemental Application (Pharmacyclics LLC)
FDA approved a supplemental application for IMBRUVICA (ibrutinib) filed by Pharmacyclics LLC. The document indicates FDA action on a supplem…
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CLINICAL_TRIALS trial_result · 2016-03-16Clinical Trial Update: Intensified Rituimab Prephase Before FCR in Untreated B-CLL [Phase 2]
A phase 2 trial of intensified rituximab prephase before FCR therapy in untreated chronic lymphocytic leukemia has completed.
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EMA safety_alert · 2016-03-11EMA reviews cancer medicine Zydelig
The EMA reviews the cancer medicine Zydelig (idelalisib) for potential safety concerns and evaluates available data.