Chronic Lymphocytic Leukemia
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS withdrawal · 2016-03-02Clinical Trial Update: Pharmacokinetics (PK), Pharmacodynamics (PD), Safety, Tolerability of Multiple Dose Regimens of MT-3724 for the Treatment of Patients With Relapsed Chronic B-cell Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 1]
Phase 1 trial of MT-3724 for relapsed chronic lymphocytic leukemia or small lymphocytic lymphoma has been withdrawn; no results are reported…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Safety and Efficacy of POL6326 for Mobilization/Transplant of Sibling Donor in Patients With Hematologic Malignancies [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating safety and efficacy of POL6326 for mobilization and transplant in hematologic malignancies has completed…
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CLINICAL_TRIALS trial_result · 2016-02-26Clinical Trial Update: Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer [Phase 2]
Phase 2 trial update of Basiliximab to prevent graft-versus-host disease after nonmyeloablative allogeneic transplantation in blood cancers;…
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CLINICAL_TRIALS trial_result · 2016-02-23Clinical Trial Update: Phase 1 Study of Terameprocol (EM-1421) in Patients With Leukemia [Phase 1]
Phase 1 study of Terameprocol (EM-1421) in leukemia was terminated; no efficacy results were reported in this update.
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CLINICAL_TRIALS trial_result · 2016-02-08Clinical Trial Update: Treatment of B-CLL With Autologous IL2 and CD40 Ligand-Expressing Tumor Cells + Lenalidomide [Phase 1]
Phase 1 trial evaluating a combination of autologous IL-2, CD40 ligand-expressing tumor cells, and lenalidomide for B-cell chronic lymphocyt…
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CLINICAL_TRIALS research · 2016-02-04Clinical Trial Update: Protocol for the Treatment of Patients With Previously Untreated Chronic Lymphocytic Leukemia [Phase 2]
This clinical trial update outlines a Phase 2 protocol for treating patients with previously untreated chronic lymphocytic leukemia.
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Rituximab and Alemtuzumab in Treating Older Patients With Progressive Chronic Lymphocytic Leukemia [Phase 2]
Phase 2 trial evaluating rituximab and alemtuzumab in older patients with progressive chronic lymphocytic leukemia; study terminated with po…
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CLINICAL_TRIALS research · 2016-01-28Clinical Trial Update: Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by CART19 [NA]
Clinical trial update describing CART19 therapy for relapsed and/or chemotherapy-refractory B-cell malignancies with an unknown status of th…
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CLINICAL_TRIALS trial_result · 2016-01-18Clinical Trial Update: Phase I and II Study of Auranofin in Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase I/II trial of the gold compound auranofin in chronic lymphocytic leukemia and related lymphoid conditions has completed its Phase 2 …
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CLINICAL_TRIALS trial_result · 2016-01-15Clinical Trial Update: Pneumococcal Vaccine in Untreated CLL Patients [Phase 3]
A Phase 3 clinical trial assessing a pneumococcal vaccine in patients with untreated chronic lymphocytic leukemia has completed.
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: Ofatumumab and Bendamustine for Previously Treated Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating the combination of ofatumumab and bendamustine in patients with previously treated chronic lymphocytic leukemia and…
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CLINICAL_TRIALS trial_result · 2015-12-15Clinical Trial Update: A Study to Compare Subcutaneous Versus Intravenous MabThera (Rituximab) in Combination With Chemotherapy in Patients With Chronic Lymphocytic Leukemia [Phase 1]
Phase 1 trial comparing subcutaneous versus intravenous rituximab in combination with chemotherapy for chronic lymphocytic leukemia has comp…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Treatment of Chronic Lymphocytic Leukemia in Patients Previously Exposed to Rituximab [Phase 2]
A Phase 2 clinical trial evaluating treatment for chronic lymphocytic leukemia in patients who had previously received Rituximab, with resul…
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CLINICAL_TRIALS withdrawal · 2015-12-02Clinical Trial Update: A Study of Safety and Effectiveness of Bendamustine Hydrochloride in Adult Filipino Patients With Chronic Lymphocytic Leukemia
This clinical trial evaluating bendamustine hydrochloride for chronic lymphocytic leukemia in adult Filipino patients has been withdrawn.
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CLINICAL_TRIALS trial_result · 2015-11-23Clinical Trial Update: Safety, Tolerability Study of SG2000 in the Treatment of Advanced Chronic Lymphocytic Leukemia and Acute Myeloid Leukemia [Phase 1, Phase 2]
A Phase 1/2 safety and tolerability study of SG2000 for advanced chronic lymphocytic leukemia and acute myeloid leukemia has been terminated…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Ofatumumab and High-dose Methylprednisolone in Patients With Chronic Lymphocytic Leukemia (CLL) [Phase 2]
A Phase 2 trial evaluating the combination of ofatumumab and high-dose methylprednisolone in patients with chronic lymphocytic leukemia has …
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Study of Repeat Intranodal Injection of Memgen's Cancer Vaccine, Ad-ISF35, in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) [Phase 2]
Phase 2 study update for Memgen's Ad-ISF35 cancer vaccine in Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma; the trial was term…
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CLINICAL_TRIALS trial_result · 2015-11-20Clinical Trial Update: Study of Repeat Intranodal Injections of Ad-ISF35 [Phase 2]
Phase 2 study of repeat intranodal injections of Ad-ISF35 in various non-Hodgkin lymphomas was terminated; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-11-11Clinical Trial Update: Cyclophosphamide, Alvocidib, and Rituximab in Treating Patients With High Risk B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma [Phase 1]
This is a Phase 1 clinical trial update reporting results for Cyclophosphamide, Alvocidib, and Rituximab in high-risk B-cell chronic lymphoc…
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FDA approval · 2015-11-05FDA Approved: TREANDA — Supplemental Application (Cephalon, LLC)
FDA approved a supplemental application for TREANDA (bendamustine hydrochloride) submitted by Cephalon, LLC.
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CLINICAL_TRIALS trial_result · 2015-11-04Clinical Trial Update: Alvespimycin Hydrochloride in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia [Phase 1]
Phase 1 trial of Alvespimycin hydrochloride in relapsed/refractory B-cell chronic lymphocytic leukemia, prolymphocytic leukemia, and small l…
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CLINICAL_TRIALS trial_result · 2015-11-02Clinical Trial Update: FCR and Bevacizumab in the Treatment of Relapsed Chronic Lymphocytic Leukemia (CLL) [Phase 2]
Phase 2 trial evaluating the combination of FCR (fludarabine, cyclophosphamide, rituximab) with bevacizumab in relapsed chronic lymphocytic …
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CLINICAL_TRIALS trial_result · 2015-10-19Clinical Trial Update: Safety, Pharmacodynamics, Pharmacokinetics, and Efficacy of GS-9901 in Adults With Relapsed or Refractory Follicular Lymphoma, Marginal Zone Lymphoma, Chronic Lymphocytic Leukemia, or Small Lymphocytic Lymphoma [Phase 1]
Phase 1 study of GS-9901 in adults with relapsed or refractory follicular lymphoma, marginal zone lymphoma, chronic lymphocytic leukemia, or…
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CLINICAL_TRIALS trial_result · 2015-10-15Clinical Trial Update: Campath Maintenance in Chronic Lymphocytic Leukemia [NA]
This update reports that Campath (alemtuzumab) maintenance for chronic lymphocytic leukemia was terminated, with results posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: A Phase 3 Study of Ibrutinib (PCI-32765) Versus Ofatumumab in Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia [Phase 3]
Phase 3 trial updating results for ibrutinib versus ofatumumab in relapsed/refractory CLL and SLL; results posted in 2015.