Cough
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Sign up freeTop drugs studied for this disease
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FDA approval · 2020-10-08FDA Approved: PROMETHAZINE HYDROCHLORIDE AND CODEINE PHOSPHATE — Original Application (QUAGEN PHARMACEUTICALS LLC)
FDA approves Promethazine hydrochloride and codeine phosphate as an original application product by Quagen Pharmaceuticals LLC.
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FDA approval · 2020-09-30FDA Approved: BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE, AND DEXTROMETHORPHAN HYDROBROMIDE — Original Application (BIONPHARMA INC.)
FDA approved Bionpharma's original ANDA for a three-drug cough/cold product containing brompheniramine maleate, pseudoephedrine hydrochlorid…
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CLINICAL_TRIALS trial_result · 2020-09-25Clinical Trial Update: Efficacy of Pregabalin on Chronic Cough [Phase 1, Phase 2]
Clinical trial update on pregabalin for chronic cough across Phase 1 and Phase 2.
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FDA approval · 2020-07-14FDA Approved: BROMPHENIRAMINE, PSEUDOEPHEDRINE, DEXTROMETHORPHAN — Original Application (Ascend Laboratories, LLC)
FDA approves the original ANDA for a triple-ingredient cough/cold product containing brompheniramine, pseudoephedrine, and dextromethorphan …
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CLINICAL_TRIALS trial_result · 2020-06-04Clinical Trial Update: Sham CPAP vs. Straight CPAP for Chronic Cough [NA]
Clinical trial comparing Sham CPAP versus Straight CPAP for chronic cough and obstructive sleep apnea has completed with results posted.
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FDA approval · 2020-04-17FDA Approved: BROMPHENIRAMINE MALEATE, PSEUDOEPHEDRINE HYDROCHLORIDE, AND DEXTROMETHORPHAN HYDROBROMIDE — Original Application (Chartwell Governmental & Specialty RX, LLC)
FDA approved the original application for a generic combination cough/cold medicine containing brompheniramine maleate, pseudoephedrine hydr…
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CLINICAL_TRIALS trial_result · 2020-04-14Clinical Trial Update: Sub-study to Spinal Cord Stimulation to Restore Cough [NA]
A completed clinical trial investigating sub-studies of spinal cord stimulation to restore cough function in individuals with spinal cord in…
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CLINICAL_TRIALS research · 2020-04-13Clinical Trial Update: Spinal Cord Stimulation to Restore Cough [NA]
A completed clinical trial investigating spinal cord stimulation as a method to restore cough in individuals with spinal cord injury/disease…
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FDA approval · 2020-04-02FDA Approved: MUCINEX — Supplemental Application (RB Health (US) LLC)
The FDA approved a supplemental application for Mucinex (guaifenesin) from RB Health (US) LLC to update/expand the product labeling.
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CLINICAL_TRIALS trial_result · 2019-12-10Clinical Trial Update: Study of Gefapixant (MK-7264) in Acute Cough for Participants With Induced Viral Upper Respiratory Tract Infection (URTI) (MK-7264-013) [Phase 2]
A Phase 2 clinical trial of gefapixant (MK-7264) for acute cough due to induced viral URTI was terminated with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-11-25Clinical Trial Update: An 8-Week Refractory Chronic Cough Study (MK-7264-021) [Phase 2]
Phase 2 trial update for an 8-week refractory chronic cough study (MK-7264-021) completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-10-22Clinical Trial Update: Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough [Phase 2]
Phase 2 trial evaluating serlopitant for refractory chronic cough has completed with posted results.
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CLINICAL_TRIALS trial_result · 2019-10-02Clinical Trial Update: A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough [Phase 1, Phase 2]
A two-phase clinical trial evaluating GSK2798745 for chronic cough was terminated; results were posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: The Utility of feNO in the Differential Diagnosis of Chronic Cough [Phase 4]
Phase 4 clinical trial evaluating the utility of fractional exhaled nitric oxide (feNO) in differentiating chronic cough etiologies, complet…
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CLINICAL_TRIALS trial_result · 2019-07-05Clinical Trial Update: Study of Gefapixant (MK-7264) in Adult Japanese Participants With Unexplained or Refractory Chronic Cough (MK-7264-033) [Phase 2]
Phase 2 clinical trial update for gefapixant (MK-7264) in adult Japanese participants with unexplained or refractory chronic cough; study co…
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: A Dose Escalation Study of Bradanicline in Refractory Chronic Cough [Phase 2]
Phase 2 dose-escalation study of bradanicline in refractory chronic cough has completed.
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CLINICAL_TRIALS trial_result · 2019-06-20Clinical Trial Update: A Study of the Effect of 20 mg Ambroxol Hydrochloride on Acute Cough. [Phase 2]
A Phase 2 clinical trial evaluating the effect of 20 mg ambroxol hydrochloride on acute cough has completed.
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CLINICAL_TRIALS withdrawal · 2019-05-23Clinical Trial Update: Effect of Cyclodextrin on Sensory Nerve Activity: A Novel Anti-tussive Therapy [Phase 4]
A Phase 4 clinical trial investigating cyclodextrin as a novel anti-tussive therapy for cough was withdrawn.
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CLINICAL_TRIALS trial_result · 2019-04-17Clinical Trial Update: Comparison Between Oxomemazine, Guaifenesin and Potassium Iodate Versus Guaifenesin Monotherapy in Acute Cough Treatment [Phase 3]
A Phase 3 clinical trial comparing a combination of oxomemazine, guaifenesin, and potassium iodate versus guaifenesin alone for acute cough …
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CLINICAL_TRIALS trial_result · 2019-02-12Clinical Trial Update: Cough in Eastern and Central Finland [NA]
A completed clinical trial conducted by Kuopio University Hospital in Eastern and Central Finland on chronic cough.
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CLINICAL_TRIALS trial_result · 2019-01-29Clinical Trial Update: Impact of Gastroesophageal Reflux and Aspiration on Airway Inflammation and Microbiome in Children With Chronic Cough
This trial update reports on a completed study examining how gastroesophageal reflux and aspiration affect airway inflammation and the airwa…
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CLINICAL_TRIALS trial_result · 2019-01-15Clinical Trial Update: Intravenous Lidocaine to Supress of Cough Reflex During Anesthesia Emergence [Phase 3]
A Phase 3 clinical trial evaluating intravenous lidocaine to suppress cough reflex during anesthesia emergence.
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CLINICAL_TRIALS trial_result · 2018-12-24Clinical Trial Update: Does Precise Delivery of Remifentanil Decrease Coughing at Emergence From Anesthesia [Phase 4]
A Phase 4 clinical trial investigates whether precise remifentanil delivery reduces coughing during emergence from anesthesia.
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FDA approval · 2018-12-19FDA Approved: BENZONATATE — Original Application (Epic Pharma LLC)
FDA approved an original application (ANDA) for benzonatate from Epic Pharma LLC, providing a generic version of the cough suppressant.
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CLINICAL_TRIALS trial_result · 2018-11-26Clinical Trial Update: Indomethacin for Refractory Chronic Cough [Phase 3]
A Phase 3 clinical trial update for indomethacin in refractory chronic cough is reported, with unknown status.</summary>