Cough
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CLINICAL_TRIALS trial_result · 2026-07-14Clinical Trial Update: A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough [Phase 3]
A 52-week Phase 3 trial evaluating the efficacy and safety of BLU-5937 in adults with refractory chronic cough has completed.
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Efficacy of Behavioral Therapy for Chronic Refractory Cough [NA]
A clinical trial sponsored by Assiut University is evaluating the efficacy of behavioral therapy for chronic refractory cough and is current…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Swiss Paediatric Airway Cohort
Update on the Swiss Paediatric Airway Cohort. The study is currently recruiting participants for a pediatric airway investigation addressing…
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CLINICAL_TRIALS trial_result · 2026-04-15Clinical Trial Update: A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough [Phase 3]
An update on a Phase 3 trial evaluating BLU-5937 for refractory chronic cough in adults; the study is currently not recruiting.
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FDA approval · 2026-04-15FDA Approved: DEXTROMETHORPHAN POLISTIREX — Original Application (Aurohealth LLC)
The FDA approved an original-application generic product of dextromethorphan polistirex from Aurohealth LLC.
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: COllaboration REsearch on Chronic Cough (COREC): a French Multicenter Database
The COllaboration REsearch on Chronic Cough (COREC) trial, a French multicenter database study for refractory chronic cough, has been termin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough [Phase 2]
This entry reports a Phase 2 study evaluating the mechanisms of change in Behavioral Cough Suppression Therapy for refractory chronic cough …
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CLINICAL_TRIALS trial_result · 2026-03-30Clinical Trial Update: Refractory Chronic Cough Improvement Via NAL ER (RIVER) [Phase 2]
Phase 2 trial of nalbuphine ER (Haduvio) for refractory chronic cough has completed and results have been posted.
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FDA approval · 2026-03-30FDA Approved: BENZONATATE 100 MG — Original Application (MARKSANS PHARMA LIMITED)
FDA approved the original application for BENZONATATE 100 MG (and 200 MG) generic products from Marksans Pharma Limited.
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 2 Study of HW091077 in Participants With Refractory Chronic Cough Or Unexplained Chronic Cough (RCC/UCC). [Phase 2]
This update announces a Phase 2 trial of HW091077 for chronic cough that is refractory to standard treatments, which is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-20Clinical Trial Update: A Clinical Evidence Study Evaluating Quality of Life Parameters Following Treatment With Robitussin [Phase 4]
A Phase 4 study evaluated quality-of-life outcomes after Robitussin treatment in individuals with a common cold or cough. The results have b…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Biomarkers for Predicting the Response to Inhaled Corticosteroid in Patients With Chronic Cough. [NA]
The study completed an evaluation of biomarkers intended to predict which patients with chronic cough respond to inhaled corticosteroids.
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CLINICAL_TRIALS trial_result · 2026-02-17Clinical Trial Update: Study to Assess the Efficacy, Safety, and Tolerability of NOC-110 in Adults With Refractory or Unexplained Chronic Cough [Phase 2]
This ClinicalTrials.gov entry notes that NOC-110 is being studied in a Phase 2 trial for adults with refractory or unexplained chronic cough…
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures [NA]
This clinical trial update evaluates the usefulness and feasibility of using ultrasound in office-based laryngology procedures, with recruit…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance [NA]
A University Hospital Ostrava study uses high-resolution manometry with impedance to analyze swallowing mechanics in patients with reflux-re…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: A Study to Assess the Efficacy and Tolerance of HRS-2261 in Subjects With Refractory Chronic Cough [Phase 2]
Phase 2 study evaluating the efficacy and tolerability of HRS-2261 in patients with chronic cough has completed.
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough [Phase 2]
A Phase 2 clinical trial is evaluating two doses of duloxetine and amitriptyline for efficacy in refractory chronic cough and is currently r…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study to Investigate the Efficacy and Safety of SC0023, in Adults With Refractory or Unexplained Chronic Cough [NA]
The clinical trial evaluating SC0023 in adults with chronic cough has completed.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia [NA]
A recruiting clinical trial is comparing endotracheal tube suctioning versus no suctioning during emergence from general anesthesia to asses…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Canadian Consortium on Airway Mucus Occlusions in Asthma, COPD and Chronic Cough
This clinical trial update indicates a McMaster University-led study on airway mucus occlusions in asthma, COPD, and chronic cough, with rec…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Wenjuanxing-Based Multidimensional Etiologic Screening and Clinical Validation of Chronic Cough in Children
This document announces a planned clinical trial using Wenjuanxing-based multidimensional etiologic screening to study and validate chronic …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: The Performance and Safety of Petit Drill in the French Paediatric Population: a Post-market Clinical Follow-up Study
Post-market clinical follow-up study in French children assessing the performance and safety of Petit Drill; the study was terminated and re…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough [Phase 4]
Phase 4 randomized open-label 2x2 factorial trial evaluating neuromodulators and cough control therapy for refractory or unexplained chronic…
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CLINICAL_TRIALS trial_result · 2025-12-16Clinical Trial Update: A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough [Phase 2]
A Phase 2 study evaluating the efficacy, safety, pharmacokinetics, and pharmacodynamics of GDC-6599 in patients with chronic cough related t…
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EMA approval · 2025-12-08EMA Authorised: Lyfnua (gefapixant) — Merck Sharp & Dohme B.V.
EMA authorised Lyfnua (gefapixant) by Merck Sharp & Dohme B.V. for the treatment of chronic cough.