Cough
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Efficacy of Behavioral Therapy for Chronic Refractory Cough [NA]
A clinical trial sponsored by Assiut University is evaluating the efficacy of behavioral therapy for chronic refractory cough and is current…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Swiss Paediatric Airway Cohort
Update on the Swiss Paediatric Airway Cohort. The study is currently recruiting participants for a pediatric airway investigation addressing…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Mechanisms of Change in Behavioral Cough Suppression Therapy for Refractory Chronic Cough [Phase 2]
This entry reports a Phase 2 study evaluating the mechanisms of change in Behavioral Cough Suppression Therapy for refractory chronic cough …
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CLINICAL_TRIALS research · 2026-03-19Clinical Trial Update: A Phase 2 Study of HW091077 in Participants With Refractory Chronic Cough Or Unexplained Chronic Cough (RCC/UCC). [Phase 2]
This update announces a Phase 2 trial of HW091077 for chronic cough that is refractory to standard treatments, which is not yet recruiting.
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CLINICAL_TRIALS research · 2026-02-10Clinical Trial Update: Usefulness and Feasibility of Ultrasound in Office Laryngology Procedures [NA]
This clinical trial update evaluates the usefulness and feasibility of using ultrasound in office-based laryngology procedures, with recruit…
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance [NA]
A University Hospital Ostrava study uses high-resolution manometry with impedance to analyze swallowing mechanics in patients with reflux-re…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Efficacy of Two Doses of Duloxetine and Amitriptyline in Subjects With Refractory Chronic Cough [Phase 2]
A Phase 2 clinical trial is evaluating two doses of duloxetine and amitriptyline for efficacy in refractory chronic cough and is currently r…
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CLINICAL_TRIALS research · 2026-01-21Clinical Trial Update: Study to Investigate the Efficacy and Safety of SC0023, in Adults With Refractory or Unexplained Chronic Cough [NA]
The clinical trial evaluating SC0023 in adults with chronic cough has completed.
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: Endotracheal Tube Suctioning Versus No Suctioning During Emergence From General Anesthesia [NA]
A recruiting clinical trial is comparing endotracheal tube suctioning versus no suctioning during emergence from general anesthesia to asses…
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Wenjuanxing-Based Multidimensional Etiologic Screening and Clinical Validation of Chronic Cough in Children
This document announces a planned clinical trial using Wenjuanxing-based multidimensional etiologic screening to study and validate chronic …
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough [Phase 4]
Phase 4 randomized open-label 2x2 factorial trial evaluating neuromodulators and cough control therapy for refractory or unexplained chronic…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation
A pediatric clinical trial update from the Medical University of Warsaw exploring biomarkers and respiratory omics to evaluate outcomes and …
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CLINICAL_TRIALS research · 2025-09-24Clinical Trial Update: A Prospective, Randomized, Double-blind Study on the Effects of Different Anesthesia Strategies on Postoperative Cough in Patients Undergoing Video-assisted Thoracoscopic Surgery. [NA]
A prospective, randomized, double-blind study evaluating how different anesthesia strategies affect postoperative cough in patients undergoi…
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CLINICAL_TRIALS research · 2025-09-11Clinical Trial Update: Cough Management Wellness App for Refractory or Unexplained Chronic Cough [NA]
Clinical trial update for a Cough Management Wellness App targeting refractory or unexplained chronic cough, sponsored by Hyfe Inc, currentl…
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CLINICAL_TRIALS research · 2025-08-29Clinical Trial Update: The Safety, Feasibility, and Repeatability of Inhaled ATP Cough Challenges [Phase 1]
Phase 1 clinical trial updating on the safety, feasibility, and repeatability of inhaled ATP cough challenges in individuals with chronic co…
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CLINICAL_TRIALS research · 2025-08-11Clinical Trial Update: Stimulation of the Larynx to Treat Unexplained Chronic Cough [NA]
A University of Minnesota-led trial is evaluating stimulation of the larynx to treat unexplained chronic cough; the study is currently recru…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: The Mechanism Versus PPI Trial [Phase 4]
Phase 4 clinical trial update recruiting to compare a mechanism-based approach against a proton pump inhibitor for laryngopharyngeal reflux …
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough
An observational study at Hull University Teaching Hospitals NHS Trust uses a novel questionnaire to characterize cough phenotypes in patien…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Efficacy of Intramuscular Steroid Injection for Chronic Cough. [EARLY_Phase 1]
An early Phase 1 clinical trial is evaluating the efficacy of intramuscular corticosteroid injections for chronic cough and related laryngea…
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CLINICAL_TRIALS research · 2025-05-11Clinical Trial Update: Cough and Hemorrhoids
A Muğla Sıtkı Koçman University-sponsored clinical trial investigating treatments for cough and hemorrhoids is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-08Clinical Trial Update: Investigating the Role of ATP Production by Airway Epithelium in Patients With Refractory and Unexplained Chronic Cough (RCC/UCC).
This clinical trial is currently recruiting to study the role of airway epithelial ATP production in patients with refractory and unexplaine…
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CLINICAL_TRIALS research · 2025-03-06Clinical Trial Update: China Chronic Cough Registry: a Multicenter, Prospective, Observational Study
A multicenter, prospective observational registry study in China to collect data on chronic cough. The sponsor is The First Affiliated Hospi…
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CLINICAL_TRIALS research · 2025-02-07Clinical Trial Update: Neuroinflammatory Interactions of ATP and P2X3 Receptor in the Airways of Chronic Cough Patients
A clinical trial sponsored by Imperial College London is investigating neuroinflammatory interactions of ATP and the P2X3 receptor in the ai…
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CLINICAL_TRIALS research · 2025-01-29Clinical Trial Update: The Real-world Treatment Satisfaction by Gefapixiant in RCC [NA]
This entry notes an ongoing real-world study evaluating treatment satisfaction with Gefapixiant in chronic cough; recruitment is currently o…
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CLINICAL_TRIALS research · 2025-01-20Clinical Trial Update: Chronic COUGH Management in Interstitial Lung DisEase [NA]
Clinical trial update for NCT06782893, a study on chronic cough management in interstitial lung disease sponsored by Aveiro University, curr…