Chordoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Children and Adults With Chordoma
Clinical trial update indicating a study on chordoma in children and adults is currently recruiting, sponsored by the National Cancer Instit…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Genetic Clues to Chordoma Etiology: A Protocol to Identify Sporadic Chordoma Patients for Studies of Cancer-Susceptibility Genes
An NCI protocol to identify sporadic chordoma patients for future studies of cancer-susceptibility genes.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Clinical Genetics Branch Eligibility Screening Survey
National Cancer Institute conducts an eligibility screening survey for a clinical trial spanning multiple cancer predisposition conditions, …
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors [Phase 1, Phase 2]
A clinical trial update on a Phase 1/2 study of combining tazemetostat with nivolumab and ipilimumab in INI1/SMARCB1-deficient and SMARCA4-d…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Chordoma [Phase 2]
A Phase 2 clinical trial update for BL-B01D1 in patients with locally advanced or metastatic chordoma; the study is currently not recruiting…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors [Phase 1, Phase 2]
Clinical trial update of a tiragolumab plus atezolizumab combination for relapsed or refractory SMARCB1/SMARCA4-deficient tumors, spanning P…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: A Study of ERAS-601 in People With Chordoma [Phase 1, Phase 2]
This clinical trial update covers ERAS-601 in people with chordoma and notes that the Phase 1/Phase 2 study is active but not currently recr…
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone
A Mayo Clinic-sponsored trial is evaluating carbon ion therapy, surgery, and proton therapy for pelvic sarcomas involving bone. Recruitment …
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CLINICAL_TRIALS research · 2026-03-11Clinical Trial Update: Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating alpha/beta T and B cell depletion with zoledronic acid for solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: BLESSED: Expanded Access for DNG64-CAR-V for Advanced Pancreatic Cancer, Sarcoma and Carcinoma of Breast
Expanded access (compassionate use) for the DNG64-CAR-V cell therapy in patients with advanced pancreatic cancer, various sarcoma subtypes, …
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma [Phase 2]
This document reports a Phase 2 clinical trial update evaluating cetuximab for advanced unresectable or metastatic chordoma.
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CLINICAL_TRIALS research · 2026-01-23Clinical Trial Update: Hypofractionated Protontherapy in Chordomas and Chondrosarcomas of the Skull Base [NA]
A clinical trial is recruiting to evaluate hypofractionated proton therapy for skull base chordomas and chondrosarcomas.
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CLINICAL_TRIALS research · 2026-01-06Clinical Trial Update: Nivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastatic Chordoma [Phase 1]
This Phase 1 trial investigates nivolumab with or without stereotactic radiosurgery for chordoma; the study is currently active but not recr…
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CLINICAL_TRIALS research · 2026-01-02Clinical Trial Update: Sacral Chordoma: Surgery Versus Definitive Radiation Therapy in Primary Localized Disease [NA]
Clinical trial evaluating surgery versus definitive radiation therapy for primary localized sacral chordoma; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Nilotinib With Radiation for High Risk Chordoma [Phase 1]
This Phase 1 trial update reports the combination of nilotinib with radiation for high-risk chordoma. The study status is completed.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers [Phase 2]
This update describes a Phase 2 study of the combination of nivolumab and ipilimumab in children and young adults with INI1-negative cancers…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Proton Beam Therapy for Chordoma Patients [Phase 2]
A Phase 2 clinical trial is investigating proton beam therapy for chordoma. The study status is ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-12-05Clinical Trial Update: Proton Radiation for Chordomas and Chondrosarcomas [NA]
This clinical trial update notes that a proton radiation therapy study for chordoma and chondrosarcoma has completed and results have been p…
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CLINICAL_TRIALS trial_result · 2025-11-14Clinical Trial Update: A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies. [Phase 1]
This Phase 1 trial of FAZ053 as a single agent and in combination with PDR001 in patients with advanced malignancies has been terminated.
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma
A Johns Hopkins-led trial is exploring personalized biomarkers during neoadjuvant radiation therapy for chordoma at spinal and sacral sites …
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Descriptive Cohort of French Patients Treated With Carbonetherapy Since October 2010 Outside PHRC-ETOILE
Describes a descriptive cohort of French patients treated with carbon ion therapy for various cancers, reported outside a PHRC-ETOILE progra…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Long-Term Longitudinal QoL in Patients Undergoing EEA
ClinicalTrials.gov registry entry from Ohio State University indicates ongoing recruitment for a long-term quality-of-life study in patients…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: A Study of Tazemetostat in Adult Participants With Soft Tissue Sarcoma [Phase 2]
Phase 2 study of tazemetostat in adult participants with soft tissue sarcoma, including rhabdoid tumors, has completed and results were post…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: TAEK-VAC-HerBy Vaccine for Brachyury and HER2 Expressing Cancer [Phase 1]
This is a Phase 1 trial update for Bavarian Nordic's TAEK-VAC-HerBy Vaccine targeting brachyury and HER2-expressing cancers, including chord…
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CLINICAL_TRIALS withdrawal · 2025-02-21Clinical Trial Update: QUILT-3.091 NANT Chordoma Vaccine vs Radiation in Subjects With Unresectable Chordoma. [Phase 1, Phase 2]
The Phase 1/2 trial QUILT-3.091 evaluating the NANT Chordoma Vaccine versus radiation for unresectable chordoma has been withdrawn.