Chordoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-02-17Clinical Trial Update: Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers [Phase 1, Phase 2]
Phase 1/2 trial update evaluating nivolumab plus ABI-009 (nab-rapamycin) in patients with advanced sarcoma and selected cancers, with result…
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CLINICAL_TRIALS trial_result · 2025-02-13Clinical Trial Update: Afatinib in Locally Advanced and Metastatic Chordoma [Phase 2]
A Phase 2 trial evaluating Afatinib for locally advanced and metastatic chordoma has completed.
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CLINICAL_TRIALS research · 2025-01-27Clinical Trial Update: Pembrolizumab and Pemetrexed for Progressive Chordoma [Phase 2]
Saint John's Cancer Institute is conducting a Phase 2 trial of pembrolizumab in combination with pemetrexed for progressive chordoma; the st…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Analysis of the Toxicity and Efficacy of Daily 1 vs 2 Beam Proton Therapy [NA]
This clinical trial update outlines a study comparing daily 1-beam versus 2-beam proton therapy to assess toxicity and efficacy in chordoma,…
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CLINICAL_TRIALS research · 2024-08-21Clinical Trial Update: Multi-parametric Imaging in Personalized Radiotherapy
This update notes that the study is currently recruiting to investigate multi-parametric imaging for personalized radiotherapy in skull base…
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CLINICAL_TRIALS trial_result · 2024-05-20Clinical Trial Update: QUILT-3.011 Phase 2 Yeast-Brachyury Vaccine Chordoma [Phase 2]
Phase 2 study of QUILT-3.011 yeast-brachyury vaccine for chordoma has completed; results were posted on 2024-05-20.
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CLINICAL_TRIALS trial_result · 2024-04-16Clinical Trial Update: Nivolumab and Relatlimab in Treating Participants With Advanced Chordoma [Phase 2]
Phase 2 trial evaluating nivolumab and relatlimab in chordoma patients has completed enrollment and study status.
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CLINICAL_TRIALS trial_result · 2024-01-23Clinical Trial Update: Trial of Palbociclib in Second Line of Advanced Sarcomas With CDK4 Overexpression. [Phase 2]
A Phase 2 trial evaluating palbociclib in second-line treatment of advanced sarcomas with CDK4 overexpression; current status unknown.
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CLINICAL_TRIALS trial_result · 2023-11-20Clinical Trial Update: Apatinib Combined With Camrelizumab in Treating Participants With Advanced Chordoma [Phase 2]
Phase 2 trial evaluating apatinib in combination with camrelizumab for advanced chordoma; current status not disclosed.
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CLINICAL_TRIALS trial_result · 2023-04-14Clinical Trial Update: BN Brachyury and Radiation in Chordoma [Phase 2]
Phase 2 trial update evaluating BN Brachyury with radiation for chordoma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-03-27Clinical Trial Update: CDK4/6 Inhibition in Locally Advanced/Metastatic Chordoma [Phase 2]
Phase 2 trial evaluating CDK4/6 inhibition in locally advanced or metastatic chordoma has been completed.
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CLINICAL_TRIALS trial_result · 2020-06-18Clinical Trial Update: Stereotactic Body Radiotherapy for Spine Tumors [NA]
Clinical trial update on stereotactic body radiotherapy for spine tumors with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2019-08-05Clinical Trial Update: Anlotinib Hydrochloride Versus Imatinib Mesylate in Locally Advanced, Unresectable or Metastatic Chordoma [Phase 2]
Phase 2 clinical trial comparing anlotinib hydrochloride to imatinib mesylate in locally advanced, unresectable, or metastatic chordoma; cur…
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CLINICAL_TRIALS trial_result · 2018-11-23Clinical Trial Update: Trial of Dasatinib in Advanced Sarcomas [Phase 2]
Phase 2 trial update for dasatinib in advanced sarcomas, with completed status and results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-03-21Clinical Trial Update: HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors [Phase 1]
This update reports the completion of a Phase 1 clinical trial evaluating HSV-1716 in patients with non-CNS solid tumors, including rhabdomy…
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CLINICAL_TRIALS trial_result · 2017-11-29Clinical Trial Update: Amifostine to Protect From Side Effects of PSCT in Treating Patients With Solid Tumors [Phase 1]
A Phase 1 trial evaluating amifostine to protect against side effects of peripheral stem cell transplantation in patients with solid tumors …
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CLINICAL_TRIALS trial_result · 2017-08-14Clinical Trial Update: Proton Therapy for Chordomas and/or Chondrosarcomas
A completed clinical trial evaluated proton therapy for chordoma and chondrosarcoma.
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CLINICAL_TRIALS trial_result · 2017-06-16Clinical Trial Update: Charged Particle RT for Chordomas and Chondrosarcomas of the Base of Skull or Cervical Spine [Phase 1, Phase 2]
This clinical trial update reports on a Phase 1/Phase 2 study evaluating charged particle radiotherapy for chordoma and chondrosarcoma at th…
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CLINICAL_TRIALS trial_result · 2017-02-23Clinical Trial Update: Efficacy and Safety of Imatinib in Chordoma [Phase 2]
Phase 2 trial evaluating the efficacy and safety of Imatinib for chordoma has completed.
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CLINICAL_TRIALS trial_result · 2017-02-03Clinical Trial Update: Hypoxia-positron Emission Tomography (PET) and Intensity Modulated Proton Therapy (IMPT) Dose Painting in Patients With Chordomas [NA]
This clinical trial evaluated hypoxia-PET guided dose painting with intensity-modulated proton therapy in chordoma patients and has complete…
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CLINICAL_TRIALS trial_result · 2013-09-20Clinical Trial Update: Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer [NA]
This clinical trial update concerns a pediatric cancer study evaluating Polyvinylpyrrolidone-Sodium Hyaluronate Gel to reduce pain from oral…
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CLINICAL_TRIALS research · 2012-12-27Clinical Trial Update: Study of Imatinib, a Platelet-derived Growth Factor Receptor Inhibitor, and LBH589, a Histone Deacetylase Inhibitor, in the Treatment of Newly Diagnosed and Recurrent Chordoma [Phase 1]
A Phase 1 clinical trial investigates the combination of imatinib and LBH589 (panobinostat) for newly diagnosed and recurrent chordoma; curr…
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CLINICAL_TRIALS research · 2010-08-17Clinical Trial Update: Trial of Proton Versus Carbon Ion Radiation Therapy in Patients With Chordoma of the Skull Base [Phase 3]
A Phase 3 study compares proton therapy with carbon ion radiation therapy for skull base chordoma; the current status of the trial is not pr…