Cholestasis
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CLINICAL_TRIALS trial_result · 2016-05-10Clinical Trial Update: Inter-regional Cohort of Neonatal and Infant Cholestasis in the Greater Southwest Region
This clinical trial in neonates and infants with cholestasis, sponsored by University Hospital, Toulouse, has been terminated.
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CLINICAL_TRIALS trial_result · 2016-02-09Clinical Trial Update: Compassionate Use of Omegaven IV Fat Emulsion [Phase 2]
Phase 2 compassionate-use trial of Omegaven IV fat emulsion for cholestasis, including total parenteral nutrition-induced cholestasis, was t…
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CLINICAL_TRIALS trial_result · 2015-11-23Clinical Trial Update: Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants [NA]
The clinical trial evaluating cyclic parenteral nutrition to prevent parenteral nutrition-associated cholestasis in infants was terminated.
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants [NA]
A randomized study evaluated tauroursodeoxycholic acid as prophylaxis for cholestasis in infants receiving total parenteral nutrition; the t…
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CLINICAL_TRIALS trial_result · 2015-03-25Clinical Trial Update: Sincalide (Cholecystokinin Octapeptide) Versus Placebo in Neonates at High Risk for Developing Parenteral Nutrition Associated Cholestasis [NA]
A completed clinical trial comparing sincalide (cholecystokinin octapeptide) to placebo in high-risk neonates to assess prevention of parent…
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CLINICAL_TRIALS trial_result · 2015-02-23Clinical Trial Update: Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT [Phase 1]
Phase 1 study assessing biliary excretion of conjugated bile acids in humans using 11C-cholylsarcosine PET/CT; the trial was completed and r…
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CLINICAL_TRIALS trial_result · 2015-01-08Clinical Trial Update: Omegaven® as Parenteral Nutrition [NA]
Clinical trial update for Omegaven as parenteral nutrition in cholestasis; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2014-05-29Clinical Trial Update: Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis [Phase 4]
Phase 4 clinical trial evaluating the efficacy and safety of S-adenosyl-L-methionine in patients with chronic hepatitis B and cholestasis; c…
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CLINICAL_TRIALS trial_result · 2013-12-19Clinical Trial Update: Brain Manganese Deposition in High Risk Neonates
A completed Vanderbilt-led clinical trial investigated brain manganese deposition in high-risk neonates, reporting on conditions including n…
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CLINICAL_TRIALS trial_result · 2013-12-19Clinical Trial Update: Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children
This updates the status of a completed clinical trial studying neurodevelopment and neuroimaging in parenterally-fed infants and young child…
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CLINICAL_TRIALS trial_result · 2013-01-24Clinical Trial Update: A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP) [NA]
This completed randomized trial evaluated carbon dioxide versus air insufflation during ERCP in patients with cholestasis, comparing procedu…
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CLINICAL_TRIALS trial_result · 2012-12-03Clinical Trial Update: Efficacy and Safety of Omega-3 Lipid Therapy in Pediatric Patients With Parenteral Nutrition-Associated Liver Disease [Phase 2]
A Phase 2 clinical trial update evaluating the efficacy and safety of omega-3 lipid therapy in pediatric patients with parenteral nutrition–…
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CLINICAL_TRIALS trial_result · 2012-08-10Clinical Trial Update: Safety and Efficacy Study of a Caspase Inhibitor in Patients Undergoing Liver Transplantation [Phase 2]
A Phase 2 trial conducted by Conatus Pharmaceuticals evaluated the safety and efficacy of a caspase inhibitor (emricasan) in patients underg…
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CLINICAL_TRIALS trial_result · 2011-09-07Clinical Trial Update: Minimization of IntraLipid Versus Omegaven [Phase 2, Phase 3]
The document reports Phase 2 and Phase 3 clinical trials comparing Intralipid versus Omegaven for cholestasis and parenteral nutrition-assoc…
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CLINICAL_TRIALS trial_result · 2010-12-30Clinical Trial Update: Effects of Ursodeoxycholic Acid on Graft Recovery Early After Adult Liver Transplantation [NA]
This clinical trial evaluated the effects of ursodeoxycholic acid on graft recovery early after adult liver transplantation. The study statu…
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CLINICAL_TRIALS trial_result · 2010-02-09Clinical Trial Update: A Study of the WallFlex™ Biliary Fully-covered Stent for the Palliative Treatment of Malignant Bile Duct Obstruction [Phase 3]
Phase 3 study evaluating the WallFlex biliary fully-covered stent for palliation of malignant bile duct obstruction has completed and result…
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CLINICAL_TRIALS trial_result · 2010-01-13Clinical Trial Update: Treatment of Cholestatic Pruritus With Sertraline [Phase 2]
A Phase 2 trial evaluated sertraline for treatment of cholestatic pruritus in patients with liver disease and has completed.
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CLINICAL_TRIALS trial_result · 2009-01-22Clinical Trial Update: Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease [NA]
A completed clinical trial evaluating magnesium sulfate in children with reduced bone density due to chronic cholestatic liver disease, incl…
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CLINICAL_TRIALS trial_result · 2007-09-24Clinical Trial Update: A Trial of Taurine Supplementation in Parenteral Nutrition 1 [NA]
This document provides an update on a clinical trial evaluating taurine supplementation in parenteral nutrition for cholestasis; specific ph…