Cholangiocarcinoma

CLINICAL_TRIALS trial_result · 2022-08-18

Clinical Trial Update: Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence [Phase 1, Phase 2]

A clinical trial exploring adjuvant PD-1 antibody in combination with capecitabine for intrahepatic cholangiocarcinoma at high risk of recur…

CLINICAL_TRIALS trial_result · 2022-07-15

Clinical Trial Update: A Phase II, Single Arm Study of BGJ398 in Patients With Advanced Cholangiocarcinoma [Phase 2]

Phase II, single-arm study of BGJ398 in advanced cholangiocarcinoma with FGFR2 mutation was terminated; results posted in 2022.

CLINICAL_TRIALS trial_result · 2022-06-13

Clinical Trial Update: Gemcitabine Plus Cisplatin With or Without Bintrafusp Alfa (M7824) in Participants With 1L BTC [Phase 2, Phase 3]

Phase 2/3 trial evaluating gemcitabine plus cisplatin with or without bintrafusp alfa (M7824) in first-line biliary tract cancer; study term…

CLINICAL_TRIALS trial_result · 2022-04-13

Clinical Trial Update: Study of AG-120 in Previously Treated Advanced Cholangiocarcinoma With IDH1 Mutations (ClarIDHy) [Phase 3]

Phase 3 study ClarIDHy evaluating ivosidenib in IDH1-mutated advanced cholangiocarcinoma has completed enrollment with results posted in 202…

CLINICAL_TRIALS trial_result · 2022-03-24

Clinical Trial Update: A Pilot Study of Combined Immune Checkpoint Inhibition in Combination With Ablative Therapies in Subjects With Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC) [Phase 2]

Phase 2 pilot study evaluating combined immune checkpoint inhibition with ablative therapies in hepatocellular carcinoma and biliary tract c…

CLINICAL_TRIALS trial_result · 2022-03-22

Clinical Trial Update: Tisleizumab Combined With Lenvatinib and XELOX Regimen (Oxaliplatin Combined With Capecitabine) in the First-line Treatment of Advanced and Unresectable Biliary Tract Tumors [Phase 2]

Phase 2 trial evaluating tisleizumab with lenvatinib and XELOX in first-line treatment of advanced unresectable biliary tract tumors.

CLINICAL_TRIALS trial_result · 2022-02-08

Clinical Trial Update: Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors [Phase 1]

Phase 1 trial evaluating LMB-100 with tofacitinib in previously treated mesothelin-expressing solid tumors, including pancreatic adenocarcin…

CLINICAL_TRIALS trial_result · 2022-01-26

Clinical Trial Update: PD-1 Inhibitor Sintilimab Combined With Capecitabine for Adjuvant Treatment After Radical Resection of Cholangiocarcinoma. [Phase 2]

Phase 2 trial evaluating sintilimab (PD-1 inhibitor) combined with capecitabine as adjuvant treatment after radical resection of cholangioca…

CLINICAL_TRIALS trial_result · 2022-01-10

Clinical Trial Update: M7824 Monotherapy in Locally Advanced or Metastatic Second Line (2L) Biliary Tract Cancer (Cholangiocarcinoma and Gallbladder Cancer) [Phase 2]

Phase 2 trial of M7824 monotherapy in second-line biliary tract cancers (cholangiocarcinoma and gallbladder cancer) has completed with resul…

CLINICAL_TRIALS trial_result · 2021-12-16

Clinical Trial Update: A Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable or Metastatic Cholangiocarcinoma and Pancreatic Adenocarcinoma [Phase 2]

A Phase 2 trial evaluated entinostat in combination with nivolumab in patients with previously treated unresectable or metastatic cholangioc…

CLINICAL_TRIALS trial_result · 2021-12-10

Clinical Trial Update: A Study of MRG002 in the Treatment of HER2-positive Unresectable, Locally Advanced or Metastatic Biliary Tract Cancer [Phase 2]

Phase 2 clinical trial update for MRG002 in HER2-positive biliary tract cancer (advanced/metastatic, unresectable).

CLINICAL_TRIALS trial_result · 2021-12-08

Clinical Trial Update: RALOX as Second Line Treatment for Advanced Malignant Biliary System Tumor [Phase 2]

Phase II trial update for RALOX as second-line treatment in advanced malignant biliary system tumors, status not disclosed.

CLINICAL_TRIALS trial_result · 2021-10-28

Clinical Trial Update: SHR-1210 in Combination With GEMOX in Patients With Advanced BTC [Phase 2]

Phase 2 trial of SHR-1210 combined with GEMOX in advanced biliary tract cancer and cholangiocarcinoma has completed.

CLINICAL_TRIALS trial_result · 2021-10-22

Clinical Trial Update: Study of CX-4945 in Combination With Gemcitabine and Cisplatin for Frontline Treatment of Cholangiocarcinoma [Phase 1, Phase 2]

A completed Phase 1/2 trial evaluating CX-4945 in combination with gemcitabine and cisplatin for frontline treatment of cholangiocarcinoma.

CLINICAL_TRIALS trial_result · 2021-10-15

Clinical Trial Update: Personal Resilience Empowerment Program Study [NA]

Clinical trial update for a study titled Personal Resilience Empowerment Program; status completed with results posted in 2021.

CLINICAL_TRIALS trial_result · 2021-09-01

Clinical Trial Update: Neoadjuvant mFOLFOXIRI for Potentially Resectable Cholangiocarcinoma [Phase 2]

Phase 2 trial update exploring neoadjuvant mFOLFOXIRI for potentially resectable cholangiocarcinoma.

CLINICAL_TRIALS trial_result · 2021-06-04

Clinical Trial Update: Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer [Phase 2]

Phase 2 trial update of lenvatinib in previously treated advanced biliary tract cancer shows completed status; investigational targeted ther…

CLINICAL_TRIALS trial_result · 2021-06-03

Clinical Trial Update: Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer [Phase 2]

Phase 2 clinical trial evaluating apatinib plus camrelizumab in previously treated advanced biliary tract cancer shows completed status.

CLINICAL_TRIALS trial_result · 2021-04-15

Clinical Trial Update: Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination With Capecitabine and Oxaliplatin (CAPOX) in People With Advanced Biliary Tract Carcinoma (BTC) [Phase 2]

Phase 2 trial evaluating pembrolizumab in combination with CAPOX for advanced biliary tract cancer has completed with posted results.

CLINICAL_TRIALS trial_result · 2021-02-26

Clinical Trial Update: A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy [NA]

Pilot study assessing theragnostically planned liver radiation to optimize radiation therapy for liver cancer, completed with posted results…

CLINICAL_TRIALS trial_result · 2021-01-05

Clinical Trial Update: Trastuzumab in HER2-positive Biliary Tract Cancer [Phase 2]

Phase 2 clinical trial of trastuzumab in HER2-positive biliary tract cancer has completed.

CLINICAL_TRIALS trial_result · 2020-12-21

Clinical Trial Update: A Study of the Use of the Medtronic Pump and Codman Catheter to Give Chemotherapy to Patients With Colorectal Carcinoma or Cholangiocarcinoma [Phase 2]

Phase 2 trial investigating use of a Medtronic pump and Codman catheter to deliver chemotherapy in colorectal cancer and cholangiocarcinoma.

CLINICAL_TRIALS trial_result · 2020-12-02

Clinical Trial Update: mFOLFOX vs. mFOLFIRI in Advanced or Recurrent Biliary Tract Cancer Refractory to First Line [Phase 2]

Phase 2 trial comparing mFOLFOX vs. mFOLFIRI in advanced or recurrent biliary tract cancer refractory to first-line therapy has completed.

CLINICAL_TRIALS trial_result · 2020-11-17

Clinical Trial Update: First Line Gemcitabine, Cisplatin and MEK162 in Advanced Biliary Tract Carcinoma [Phase 1, Phase 2]

A Phase 1/2 trial evaluating first-line gemcitabine, cisplatin, and MEK162 in advanced biliary tract carcinoma has completed with results po…

CLINICAL_TRIALS trial_result · 2020-11-02

Clinical Trial Update: Copanlisib (BAY 80-6946) in Combination With Gemcitabine and Cisplatin in Advanced Cholangiocarcinoma [Phase 2]

Phase 2 trial of copanlisib in combination with gemcitabine and cisplatin for advanced cholangiocarcinoma completed.

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