Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors [Phase 1, Phase 2]
A safety and tolerability study of NC318 in advanced or metastatic solid tumors completed Phase 1/2 with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma [Phase 2]
Phase 2 trial evaluating a combo of DEB-TACE, lenvatinib, and pucotenlimab as conversion therapy for unresectable intrahepatic cholangiocarc…
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CLINICAL_TRIALS trial_result · 2023-11-14Clinical Trial Update: A Study of BBI503 in Adult Patients With Advanced Hepatobiliary Cancer [Phase 2]
Phase 2 trial of BBI503 in adults with advanced hepatobiliary cancer (hepatocellular carcinoma and cholangiocarcinoma) has completed.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001) [Phase 2]
Phase 2 trial evaluating niraparib in BAP1- and DDR-deficient neoplasms including mesothelioma and uveal melanoma has completed with results…
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CLINICAL_TRIALS trial_result · 2023-09-11Clinical Trial Update: PCI Treatment/Gemcitabine & Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Extrahepatic Bile Duct Cancer [Phase 2]
Phase 2 clinical trial assessing PCI treatment with gemcitabine plus chemotherapy versus chemotherapy alone in patients with inoperable extr…
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CLINICAL_TRIALS trial_result · 2023-08-22Clinical Trial Update: Safety and Tumoricidal Effect of Low Dose Foscan PDT in Patients With Inoperable Bile Duct Cancers [Phase 2]
Phase 2 clinical trial assessing safety and tumoricidal effect of low-dose Foscan PDT in inoperable bile duct cancers (cholangiocarcinoma).
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Combination of Trametinib (MEK Inhibitor) and Hydroxychloroquine (HCQ) (Autophagy Inhibitor) in Patients With KRAS Mutation Refractory Bile Tract Carcinoma (BTC). [Phase 2]
Phase 2 trial evaluating trametinib plus hydroxychloroquine in KRAS-mutant biliary tract cancers was terminated with posted results.
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CLINICAL_TRIALS trial_result · 2023-07-11Clinical Trial Update: Atezolizumab With or Without Cobimetinib in Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed by Surgery or Gallbladder Cancer [Phase 2]
Phase 2 trial evaluating atezolizumab with or without cobimetinib in unresectable gallbladder carcinoma and metastatic cholangiocarcinoma; s…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: HAIC With Oxaliplatin, 5-FU and Bevacizumab Plus Intravenous Toripalimab for Advanced BTC [Phase 2]
A Phase 2 trial evaluating hepatic arterial infusion chemotherapy with oxaliplatin, 5-fluorouracil, and bevacizumab in combination with intr…
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Durvalumab and Tremelimumab With Gemcitabine or Gemcitabine/Cisplatin Compared to Gemcitabine/Cisplatin in CCA Patients [Phase 2]
Phase 2 trial update comparing durvalumab and tremelimumab with gemcitabine or gemcitabine/cisplatin versus gemcitabine/cisplatin in cholang…
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CLINICAL_TRIALS trial_result · 2023-06-15Clinical Trial Update: Ramucirumab in Treating Patients With Advanced or Metastatic, Previously Treated Biliary Cancers That Cannot Be Removed by Surgery [Phase 2]
Phase 2 clinical trial evaluating ramucirumab in advanced or metastatic biliary cancers that cannot be removed surgically; results completed…
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CLINICAL_TRIALS trial_result · 2023-05-24Clinical Trial Update: Clinical Trial of Autologous Tcm Immunotherapy in ICC [Phase 2]
Phase 2 clinical trial update for autologous Tcm immunotherapy in cholangiocarcinoma.
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CLINICAL_TRIALS trial_result · 2023-04-21Clinical Trial Update: Treatment for Bile Duct Cancer in the Liver [Phase 2]
Phase 2 clinical trial update for a treatment targeting cholangio carcinoma (bile duct cancer) in the liver; study completed.
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CLINICAL_TRIALS trial_result · 2023-04-13Clinical Trial Update: Durvalumab or Placebo in Combination With Gemcitabine/Cisplatin in Patients With 1st Line Advanced Biliary Tract Cancer (TOPAZ-1) [Phase 3]
Phase 3 TOPAZ-1 trial results for durvalumab in combination with gemcitabine/cisplatin in first-line biliary tract cancer have been posted.
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CLINICAL_TRIALS trial_result · 2023-04-10Clinical Trial Update: IMM2902 in Patients With Advanced Solid Tumors Expressing HER2 [Phase 1, Phase 2]
Phase 1/2 trial update for IMM2902 in patients with HER2-expressing advanced solid tumors including advanced solid tumors, advanced lung can…
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CLINICAL_TRIALS trial_result · 2023-03-29Clinical Trial Update: Lenvatinib Combined Pembrolizumab in Advanced Hepatobiliary Tumors [Phase 2]
Phase 2 trial evaluating lenvatinib combined with pembrolizumab in advanced hepatobiliary tumors has completed.
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CLINICAL_TRIALS trial_result · 2023-03-21Clinical Trial Update: Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers [Phase 2]
Phase 2 trial of perioperative MVT-5873, a CA 19-9 epitope–targeting monoclonal antibody, in operable CA 19-9–producing pancreatic cancers, …
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CLINICAL_TRIALS trial_result · 2023-03-14Clinical Trial Update: A Study of ICP-192 in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A clinical trial update for ICP-192 in advanced solid tumors and urothelial carcinoma (Phase 1/2). Status is unknown.
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CLINICAL_TRIALS trial_result · 2023-02-23Clinical Trial Update: Efficacy and Safety of Pemigatinib in Subjects With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma Who Failed Previous Therapy - (FIGHT-202) [Phase 2]
Phase 2 FIGHT-202 trial updates show efficacy and safety data for pemigatinib in advanced/metastatic or surgically unresectable cholangiocar…
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CLINICAL_TRIALS trial_result · 2023-01-06Clinical Trial Update: Open-Label, Dose-Escalation Study of Pemigatinib in Subjects With Advanced Malignancies - (FIGHT-101) [Phase 1, Phase 2]
Open-label, dose-escalation study of pemigatinib in advanced malignancies (FIGHT-101) completed; results posted.
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CLINICAL_TRIALS trial_result · 2022-12-09Clinical Trial Update: Feasibility of Radiotherapy and Concomitant Gemcitabine and Oxaliplatin in Locally Advanced Pancreatic Cancer and Distal Cholangiocarcinoma [Phase 2]
Phase 2 clinical trial assessing radiotherapy with concurrent gemcitabine and oxaliplatin in locally advanced, unresectable non-metastatic p…
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CLINICAL_TRIALS trial_result · 2022-12-07Clinical Trial Update: Durvalumab Combined With Chemotherapy Neoadjuvant Therapy of Biliary Tract Cancer [Phase 2]
Phase 2 clinical trial update on durvalumab combined with neoadjuvant chemotherapy for resectable biliary tract cancer.
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CLINICAL_TRIALS trial_result · 2022-12-06Clinical Trial Update: Adjuvant Capecitabine vs Gemcitabine Plus Cisplatin in Resected Extrahepatic Cholangiocarcinoma [Phase 2]
A Phase 2 trial comparing adjuvant capecitabine to a gemcitabine plus cisplatin regimen in resected extrahepatic cholangiocarcinoma has comp…
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CLINICAL_TRIALS trial_result · 2022-10-21Clinical Trial Update: Chemo Alone or in Combination With Radiation in Unresectable Cholangiocarcinoma [Phase 3]
Phase 3 trial evaluating chemotherapy alone versus chemotherapy with radiation for unresectable cholangiocarcinoma; current status not speci…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: Trial of IRE in Cholangiocarcinoma [Phase 2]
Phase 2 trial update for irreversible electroporation (IRE) in cholangiocarcinoma has completed with results posted in 2022.