Cholangiocarcinoma

CLINICAL_TRIALS trial_result · 2025-08-15

Clinical Trial Update: Gemcitabine, Cisplatin, and Nab-Paclitaxel Before Surgery in Patients With High-Risk Liver Bile Duct Cancer [Phase 2]

Phase 2 trial evaluating preoperative combination therapy with gemcitabine, cisplatin, and nab-paclitaxel for resectable cholangiocarcinoma,…

CLINICAL_TRIALS trial_result · 2025-08-08

Clinical Trial Update: Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma

This clinical trial update notes that the study evaluating preoperative lymph node evaluation in cholangiocarcinoma has completed.

CLINICAL_TRIALS trial_result · 2025-08-07

Clinical Trial Update: The Safety and Efficacy of Benmelstobart Injection in Patients With Advanced Biliary Tract Malignant Tumors [Phase 2]

A Phase 2 clinical trial is evaluating Benmelstobart Injection for advanced biliary tract cancers and the study is not yet recruiting.

CLINICAL_TRIALS trial_result · 2025-08-03

Clinical Trial Update: Study of DKN-01 and Gemcitabine/Cisplatin in Patients With Carcinoma to Primary to the Intra- or Extra-Hepatic Biliary System or Gallbladder [Phase 1]

A Phase 1 study evaluating DKN-01 in combination with gemcitabine and cisplatin for biliary tract cancers has completed (completion status r…

CLINICAL_TRIALS trial_result · 2025-07-30

Clinical Trial Update: Long-Term Follow-up Study of Subjects Treated With Autologous T Cells Using the Sleeping Beauty System to Express TCRs

Alaunos Therapeutics reports long-term follow-up data from subjects treated with autologous T cells engineered with a Sleeping Beauty system…

CLINICAL_TRIALS trial_result · 2025-07-23

Clinical Trial Update: A Study of ABC294640 Alone and in Combination With HCQ Sulfate in the Treatment of Advanced Cholangiocarcinoma [Phase 2]

Phase 2 clinical trial update evaluating ABC294640 (Opaganib) alone and in combination with hydroxychloroquine sulfate in advanced cholangio…

CLINICAL_TRIALS trial_result · 2025-07-10

Clinical Trial Update: Feasibility Study of Multi-Platform Profiling of Resected Biliary Tract Cancer

This clinical trial update reports the termination of a feasibility study evaluating multi-platform profiling of resected biliary tract canc…

CLINICAL_TRIALS trial_result · 2025-06-24

Clinical Trial Update: Laparotomy, Laparoscopy, da Vinci System

Completed clinical trial evaluating laparotomy, laparoscopy, and robotic da Vinci System approaches for stomach and pancreatic neoplasms, as…

CLINICAL_TRIALS trial_result · 2025-06-10

Clinical Trial Update: Infigratinib for the Treatment of Advanced or Metastatic Solid Tumors in Patients With FGFR Gene Mutations [Phase 2]

Phase 2 trial update on Infigratinib for FGFR-mutant advanced or metastatic solid tumors, including cholangiocarcinoma. Results posted 2025-…

CLINICAL_TRIALS trial_result · 2025-05-21

Clinical Trial Update: Domvanalimab and Zimberelimab in Advanced Liver Cancers [Phase 2]

Phase 2 trial update examining domvanalimab and zimberelimab in advanced liver cancers, including cholangiocarcinoma and hepatocellular carc…

CLINICAL_TRIALS trial_result · 2025-05-08

Clinical Trial Update: Gem+Nab-P+LEN+TIS for Advanced Unresectable BTC (GALENT-BT) [Phase 2]

Phase 2 trial update for a four-drug regimen (gemcitabine, nab-paclitaxel, lenalidomide, and tislelizumab) in advanced unresectable biliary …

CLINICAL_TRIALS trial_result · 2025-05-02

Clinical Trial Update: Fatigue and Pancreas and Bile Duct Cancer Study [EARLY_Phase 1]

An early-phase Phase 1 clinical trial studying fatigue in pancreatic cancer and cholangiocarcinoma has completed.

CLINICAL_TRIALS trial_result · 2025-05-01

Clinical Trial Update: Immunotherapy With Durva and Treme With or Without Capecitabine in Adjuvant Treatment for Biliary Tract Cancer [Phase 2]

Phase 2 clinical trial evaluating durvalumab and tremelimumab with or without capecitabine as adjuvant therapy for biliary tract cancers; th…

CLINICAL_TRIALS trial_result · 2025-04-27

Clinical Trial Update: A Study to Evaluate the Clinical Efficacy of JNJ-42756493 (Erdafitinib), A Pan-Fibroblast Growth Factor Receptor (FGFR) Tyrosine Kinase Inhibitor, In Asian Participants With Advanced Non-Small-Cell Lung Cancer, Urothelial Cancer, Esophageal Cancer Or Cholangiocarcinoma [Phase 2]

A Phase 2 study completed in Asian participants evaluated Erdafitinib, a pan-FGFR tyrosine kinase inhibitor, for efficacy in advanced non-sm…

CLINICAL_TRIALS trial_result · 2025-04-18

Clinical Trial Update: Contribution of the EyeMAX™ 11Fr (Micro-Tech) Digital Single-Operator Cholangioscope With a Wide Working Channel

This clinical trial update describes the use of the EyeMAX 11Fr digital single-operator cholangioscope with a wide working channel in evalua…

CLINICAL_TRIALS trial_result · 2025-04-16

Clinical Trial Update: A Phase 1 Study Evaluating the Safety of TRK-950 in Patients With Advanced Solid Tumors [Phase 1]

This update reports the completion of a Phase 1 study evaluating the safety of TRK-950 in patients with advanced solid tumors. The study inc…

CLINICAL_TRIALS trial_result · 2025-03-30

Clinical Trial Update: Clinical Correlation Study Between Anomalous Pancreaticobiliary Ductal Junction and Malignant Tumors of the Biliary System and the Establishment of an AI-based Automated Recognition System

This completed clinical trial investigated the relationship between anomalous pancreaticobiliary ductal junction and malignant tumors of the…

CLINICAL_TRIALS trial_result · 2025-03-25

Clinical Trial Update: A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer [Phase 1]

Phase 1 study to determine a safe and potentially effective dose of BI-905711 in patients with advanced gastrointestinal cancers, including …

CLINICAL_TRIALS trial_result · 2025-03-21

Clinical Trial Update: A Study of Tislelizumab Combined With Radiotherapy as the Second-line Treatment of Advanced Biliary Malignant Tumors [Phase 2]

A phase 2 study evaluating tislelizumab in combination with radiotherapy as a second-line treatment for advanced biliary malignant tumors (c…

CLINICAL_TRIALS trial_result · 2025-03-21

Clinical Trial Update: Clinico-demographic Profile of the Patient With Pancreaticobiliary Malignancy Undergoing ERCP in a Tertiary Care Center of Nepal

A completed clinical trial update from Kathmandu University School of Medical Sciences profiling patients with pancreaticobiliary malignanci…

CLINICAL_TRIALS trial_result · 2025-03-20

Clinical Trial Update: Clinicopathologic Characteristics, Progression, and Prognostic Analysis of IPNB

Clinical trial update examining clinicopathologic characteristics, disease progression, and prognosis in intraductal papillary neoplasm of t…

CLINICAL_TRIALS trial_result · 2025-03-20

Clinical Trial Update: PLATON - Platform for Analyzing Targetable Tumor Mutations (Pilot-study) [NA]

PLATON, a platform for analyzing targetable tumor mutations, completed its pilot study evaluating its utility across hepatocellular carcinom…

CLINICAL_TRIALS trial_result · 2025-03-18

Clinical Trial Update: Expanded Access for the Treatment of Advanced Cholangiocarcinoma With ABC294640 (Yeliva ®)

Expanded Access for ABC294640 (Yeliva) in advanced cholangiocarcinoma has been closed and is no longer available.

CLINICAL_TRIALS trial_result · 2025-02-07

Clinical Trial Update: Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements [Phase 3]

Phase 3 trial comparing futibatinib to gemcitabine-cisplatin as first-line treatment for advanced cholangiocarcinoma with FGFR2 gene rearran…

CLINICAL_TRIALS trial_result · 2025-01-24

Clinical Trial Update: Feasibility of Cryobiopsy from the Bile Duct - CRYLEO [NA]

This completed clinical trial assessed the feasibility of performing cryobiopsy of the bile duct to sample neoplastic tissue.

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