Cholangiocarcinoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Brightline-2: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder [Phase 2]
Phase 2 study update on brigimadlin (BI 907828) in biliary tract cancer, pancreatic cancer, lung cancer, and bladder cancer; the trial has c…
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: Pembrolizumab in Combination With Lenvatinib in Patients With Advanced Biliary Tract Carcinoma [Phase 2]
Phase 2 trial evaluating pembrolizumab in combination with lenvatinib for advanced biliary tract carcinoma. The study has completed.
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CLINICAL_TRIALS trial_result · 2026-01-21Clinical Trial Update: The Comparison of Miniinvasive and Open Pancreaticoduodenectomy for Cancer Pancreaticobiliary Zone [NA]
A completed clinical trial comparing minimally invasive versus open pancreaticoduodenectomy for pancreaticobiliary cancers.
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Preoperative Right Hepatic Artery Embolization for Locally Advanced Bismuth IIIb and IV Perihilar Cholangiocarcinoma [NA]
This clinical trial update covers preoperative right hepatic artery embolization for locally advanced, non-resectable Bismuth IIIb/IV perihi…
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CLINICAL_TRIALS trial_result · 2026-01-14Clinical Trial Update: Imfinzi BTC Japan PMS_Japan Post-Marketing Surveillance (PMS) Study - CEI/SCEI
Durvalumab (Imfinzi) is studied in a Japan post-marketing surveillance PMS for biliary tract cancer; the study has completed.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Efficacy and Safety of TT-00420 (Tinengotinib) Tablets Versus Chemotherapy in Patients With Advanced Intrahepatic Cholangiocarcinoma Harboring FGFR2 Fusions/Rearrangements or Mutations [Phase 3]
A Phase 3 trial evaluating Tinengotinib (TT-00420) versus chemotherapy in patients with advanced intrahepatic cholangiocarcinoma harboring F…
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors [Phase 1]
Phase 1 study of Felmetatug Vedotin (SGN-B7H4V) in advanced solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2026-01-09Clinical Trial Update: Liver and Biliary Tumor Tissue Registry
Mayo Clinic's Liver and Biliary Tumor Tissue Registry (NCT02917759) has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: New Prospective Expanded German Registry of Incidental Gallbladder Carcinoma (PERSUASION)- a Permanent Platform Including All Kind of Biliary Tract Cancers (BTC)
The PERSUASION registry, a prospective German platform for biliary tract cancers including gallbladder carcinoma, has completed its expanded…
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CLINICAL_TRIALS trial_result · 2025-12-22Clinical Trial Update: NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma [Phase 1]
Phase 1 trial of NXP800 for advanced or metastatic cholangiocarcinoma has been terminated.
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CLINICAL_TRIALS trial_result · 2025-12-09Clinical Trial Update: A Phase 2 Study of Ivosidenib in Previously Treated Japanese Subjects With Nonresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation [Phase 2]
Phase 2 study of Ivosidenib in Japanese patients with nonresectable or metastatic IDH1-mutant cholangiocarcinoma. Results were posted on 202…
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CLINICAL_TRIALS trial_result · 2025-12-04Clinical Trial Update: Senior Adult Hepatobiliary Prehab Study [NA]
This update covers the Senior Adult Hepatobiliary Prehab Study, a trial in hepatobiliary cancer including cholangiocarcinoma; the study stat…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies [NA]
A clinical trial is evaluating high dose-rate brachytherapy for unresectable primary and metastatic liver malignancies. The study is current…
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CLINICAL_TRIALS trial_result · 2025-11-10Clinical Trial Update: Phase I/II Study of Autologous T Cells to Express T-Cell Receptors (TCRs) in Subjects With Solid Tumors [Phase 1, Phase 2]
Phase I/II trial of autologous T cells engineered to express T-cell receptors (TCRs) in patients with solid tumors was terminated with resul…
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CLINICAL_TRIALS trial_result · 2025-10-21Clinical Trial Update: An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies [Phase 1]
Open-label Phase 1 safety and tolerability study of INCB062079 in patients with advanced hepatocellular carcinoma and other malignancies; st…
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: Nal-IRI With 5-fluorouracil (5-FU) and Leucovorin or Gemcitabine Plus Cisplatin in Advanced Biliary-tract Cancer [Phase 2]
This clinical trial update notes the completion of a phase 2 study evaluating nanoliposomal irinotecan (nal-IRI) with either 5-fluorouracil/…
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: EchoTip AcuCore Post-Market Clinical Study
Completed post-market clinical study update for the EchoTip AcuCore device, detailing the completion of the post-market evaluation.
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…
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CLINICAL_TRIALS trial_result · 2025-09-18Clinical Trial Update: Tissue Adhesive Glue Modified Cyanoacrylate (Glubran® 2) in Soft Pancreas [Phase 3]
Phase 3 clinical trial evaluating Glubran 2, a modified cyanoacrylate tissue adhesive, for use in soft pancreas during pancreatic and periam…
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CLINICAL_TRIALS trial_result · 2025-09-09Clinical Trial Update: Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers [Phase 2]
Phase 2 trial evaluating tucatinib plus trastuzumab with oxaliplatin-based chemotherapy or pembrolizumab-containing regimens for HER2-positi…
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CLINICAL_TRIALS trial_result · 2025-08-27Clinical Trial Update: A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer [Phase 1, Phase 2]
A Phase 1/2 study of TC-510 from TCR2 Therapeutics in mesothelin-expressing cancers is active but not recruiting, spanning multiple indicati…
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: Biomarker Discovery in Patients With Advanced Biliary Tract Cancer
A completed clinical trial update describing biomarker discovery efforts in patients with advanced biliary tract cancer, including cholangio…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma [Phase 3]
Phase 3 trial evaluating pemigatinib versus chemotherapy in unresectable or metastatic cholangiocarcinoma was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of LY3039478 in participants with advanced or metastatic solid tumors was terminated. Results were posted on 2025-08-21.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: En Bloc Resection of the Liver and Pancreas With a "Non-touch" Technique Followed by Liver Transplantation to Improve the Overall Survival in Patients With Non-resectable Hilar Cholangiocarcinoma Beyond the Mayo Clinic Transplant Criteria [NA]
This clinical trial update outlines a surgical strategy of en bloc resection of the liver and pancreas using a non-touch technique, followed…